Publications

Nucleic acids research

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.

01-07-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

01-07-2010

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Genetic testing in Li-Fraumeni syndrome: uptake and psychosocial consequences.

20-06-2010

Human antibodies

Pharmacokinetics of rituximab in patients with CD20 positive B-cell malignancies.

18-06-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Inhibition of the PI3K pathway: hope we can believe in?

15-06-2010

The Journal of experimental medicine

One naive T cell, multiple fates in CD8+ T cell differentiation.

07-06-2010

Medical physics

Catching errors with in vivo EPID dosimetry.

01-06-2010

Journal of medical genetics

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.

01-06-2010

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

01-06-2010

Current opinion in cell biology

Genome-nuclear lamina interactions and gene regulation.

01-06-2010

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.

01-06-2010

Molecular cancer research : MCR

The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

01-06-2010

Nature structural & molecular biology

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

01-06-2010

Molecular cell

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.

28-05-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

British journal of clinical pharmacology

Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.

01-05-2010

Clinical genetics

Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.

01-05-2010

European journal of cancer (Oxford, England : 1990)

Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer.

01-05-2010

Cancer

Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial.

01-05-2010

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

01-05-2010

Annals of surgical oncology

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature.

01-05-2010

Proteins

Structure of human CLIC3 at 2 A resolution.

01-05-2010

The Journal of biological chemistry

Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.

23-04-2010

BMC genomics

Major role for mRNA stability in shaping the kinetics of gene induction.

21-04-2010

Proceedings of the National Academy of Sciences of the United States of America

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.

20-04-2010

Journal of cell science

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

15-04-2010

Cell

It's diagnostics, stupid.

02-04-2010

Cell

Drugging drug resistance.

02-04-2010

Breast cancer research and treatment

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

01-04-2010

Psycho-oncology

The impact of different definitions and reference groups on the prevalence of cognitive impairment: a study in postmenopausal breast cancer patients before the start of adjuvant systemic therapy.

01-04-2010

Annals of surgery

MRI-model to guide the surgical treatment in breast cancer patients after neoadjuvant chemotherapy.

01-04-2010

Molecular cancer research : MCR

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

01-04-2010

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The role of FDG PET/CT in patients with locoregional breast cancer recurrence: a comparison to conventional imaging techniques.

01-04-2010

Annals of oncology : official journal of the European Society for Medical Oncology

The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age.

01-04-2010

Investigational new drugs

Disposition and toxicity of trabectedin (ET-743) in wild-type and mdr1 gene (P-gp) knock-out mice.

01-04-2010

Molecular pharmacology

Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.

01-04-2010

European journal of clinical investigation

microRNAs, RNA binding proteins and cancer.

01-04-2010

Molecular imaging and biology

Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer.

01-04-2010

Nature cell biology

BRD7 is a candidate tumour suppressor gene required for p53 function.

01-04-2010

Investigational new drugs

Dose-finding and pharmacokinetic study of orally administered indibulin (D-24851) to patients with advanced solid tumors.

01-04-2010

European journal of cancer (Oxford, England : 1990)

Trends in incidence, treatment and survival of gastric adenocarcinoma between 1990 and 2007: a population-based study in the Netherlands.

01-04-2010

Seminars in radiation oncology

Adaptive radiotherapy for lung cancer.

01-04-2010

Health and quality of life outcomes

Effects of mode of administration (MOA) on the measurement properties of the EORTC QLQ-C30: a randomized study.

30-03-2010

Cancer cell

PICS-ure this: prosenescence therapy?

16-03-2010

Urologia internationalis

Pim1 regulates androgen-dependent survival signaling in prostate cancer cells.

11-03-2010

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial.

10-03-2010

Oncology letters

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer.

01-03-2010

Cell death and differentiation

Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.

01-03-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Postoperative chemoradiotherapy in gastric cancer--a phase I-II study of radiotherapy with dose escalation of weekly cisplatin and daily capecitabine chemotherapy.

01-03-2010

AAPS PharmSciTech

Naked plasmid DNA formulation: effect of different disaccharides on stability after lyophilisation.

01-03-2010