Publications

Cancer Research

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach

26-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients.

15-01-2010

Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010

Nederlands tijdschrift voor geneeskunde

[Secondary use of human tissue: consent and better information required].

07-01-2010

Oncogene

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

07-01-2010

Proceedings of the National Academy of Sciences of the United States of America

Recombination-induced tag exchange to track old and new proteins.

05-01-2010

Laboratory animals

Validation of intratracheal instillation of lung tumour cells in mice using single photon emission computed tomography/computed tomography imaging.

01-01-2010

Breast cancer research and treatment

Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response.

01-01-2010

PLoS computational biology

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

01-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

01-01-2010

The Journal of pathology

A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis.

01-01-2010

Nucleosides, nucleotides & nucleic acids

Facile small scale synthesis of nucleoside 5'-phosphate mixtures.

01-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.

01-01-2010

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The use of fluorescent dyes and probes in surgical oncology.

01-01-2010

BioEssays : news and reviews in molecular, cellular and developmental biology

G protein-coupled receptors: the inside story.

01-01-2010

The Journal of clinical investigation

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.

01-01-2010

Clinical pharmacology and therapeutics

Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel.

01-01-2010

Biomedical chromatography : BMC

High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature.

01-01-2010

Annals of oncology : official journal of the European Society for Medical Oncology

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment.

01-01-2010

European journal of cancer (Oxford, England : 1990)

New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System.

01-01-2010

Genes & development

Tumorigenicity of the miR-17-92 cluster distilled.

01-01-2010

Proc Natl Acad Sci U S A: Proceedings of the National Academy of Sciences of the United States of America

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

22-12-2009

Breast cancer research : BCR

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients.

22-12-2009

Oncogene

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer.

17-12-2009

Journal of the National Cancer Institute

Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer.

16-12-2009

Journal of the National Cancer Institute

Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

16-12-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

ABCC2, ABCC3, and ABCB1, but not CYP3A, Protect against Trabectedin-Mediated Hepatotoxicity.

15-12-2009

The Biochemical journal

Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.

14-12-2009

Journal of pharmaceutical and biomedical analysis

The bioanalysis of the monoclonal antibody trastuzumab by high-performance liquid chromatography with fluorescence detection after immuno-affinity purification from human serum.

05-12-2009

The EMBO journal

Histone H1 binding is inhibited by histone variant H3.3.

02-12-2009

Methods in molecular biology (Clifton, N.J.)

Studying drug resistance using genetically engineered mouse models for breast cancer.

02-12-2009

International journal of radiation oncology, biology, physics

Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.

01-12-2009

Molecular oncology

Review on early technology assessments of nanotechnologies in oncology.

01-12-2009

Cancer treatment reviews

High-grade glioma mouse models and their applicability for preclinical testing.

01-12-2009

Biochimica et biophysica acta

Metastasis mechanisms.

01-12-2009

Drug metabolism and disposition: the biological fate of chemicals

Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.

01-12-2009

Psycho-oncology

Long-term cancer survivors experience work changes after diagnosis: results of a population-based study.

01-12-2009

Biochimica et biophysica acta

Therapeutic options for triple-negative breast cancers with defective homologous recombination.

01-12-2009

Molecular cancer therapeutics

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

01-12-2009

Biomedical chromatography : BMC

The bioanalysis of vinorelbine and 4-O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass-spectrometry.

01-12-2009

Cancer research

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.

01-12-2009

Proceedings of the National Academy of Sciences of the United States of America

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.

24-11-2009

The Journal of experimental medicine

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.

23-11-2009

British journal of cancer

Preclinical mouse models for BRCA1-associated breast cancer.

17-11-2009

Oncology (Williston Park, N.Y.)

The multidisciplinary approach to colorectal cancer liver metastases.

15-11-2009

International journal of radiation oncology, biology, physics

Strategies for online organ motion correction for intensity-modulated radiotherapy of prostate cancer: prostate, rectum, and bladder dose effects.

15-11-2009

Cell

Transformation locked in a loop.

13-11-2009

British journal of cancer

A trial of consent procedures for future research with clinically derived biological samples.

03-11-2009

Nucleic acids research

Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.

01-11-2009

The Lancet. Oncology

Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.

01-11-2009