Publications

Nature cell biology

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

21-08-2011

Oncogene

Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53.

18-08-2011

Chembiochem : a European journal of chemical biology

Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression.

16-08-2011

Human molecular genetics

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

15-08-2011

Nature reviews. Cancer

MicroRNA regulation by RNA-binding proteins and its implications for cancer.

05-08-2011

Human brain mapping

Cerebral hyporesponsiveness and cognitive impairment 10 years after chemotherapy for breast cancer.

01-08-2011

Breast cancer research and treatment

Unfavourable pattern of metastases in M0 breast cancer patients during 1978-2008: a population-based analysis of the Munich Cancer Registry.

01-08-2011

Translational oncology

Immunohistochemical detection of the CXCR4 expression in tumor tissue using the fluorescent peptide antagonist Ac-TZ14011-FITC.

01-08-2011

Drug metabolism and disposition: the biological fate of chemicals

Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.

01-08-2011

Cancer discovery

Functional subtyping of breast cancer.

01-08-2011

Nucleic acids research

Computational identification of insertional mutagenesis targets for cancer gene discovery.

01-08-2011

European journal of cancer (Oxford, England : 1990)

Impact of chemotherapy on health status and symptom burden of colon cancer survivors: a population-based study.

01-08-2011

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

01-08-2011

Journal of structural biology

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.

01-08-2011

Journal of structural biology

Investigating a macromolecular complex: the toolkit of methods.

01-08-2011

International journal of cancer

Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7.

15-07-2011

Journal of medicinal chemistry

Structure-based design of novel boronic acid-based inhibitors of autotaxin.

14-07-2011

J Clin Invest: The Journal of clinical investigation

Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance

11-07-2011

Nucleic acids research

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.

01-07-2011

Clinical pharmacology and therapeutics

Population pharmacokinetic-pharmacodynamic analysis of trastuzumab-associated cardiotoxicity.

01-07-2011

Breast cancer research and treatment

Improved survival of patients with primary distant metastatic breast cancer in the period of 1995-2008. A nationwide population-based study in the Netherlands.

01-07-2011

Annals of oncology : official journal of the European Society for Medical Oncology

An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients.

01-07-2011

The British journal of surgery

Impact of concentration of oesophageal and gastric cardia cancer surgery on long-term population-based survival.

01-07-2011

Cancer cell

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

14-06-2011

The oncologist

Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.

11-06-2011

The oncologist

Part 4: pharmacogenetic variability in anticancer pharmacodynamic drug effects.

11-06-2011

British journal of cancer

A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.

07-06-2011

The oncologist

Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.

03-06-2011

The oncologist

Part 1: background, methodology, and clinical adoption of pharmacogenetics.

03-06-2011

The oncologist

Trastuzumab.

03-06-2011

The AAPS journal

Evaluation of α2-integrin expression as a biomarker for tumor growth inhibition for the investigational integrin inhibitor E7820 in preclinical and clinical studies.

01-06-2011

International journal of radiation oncology, biology, physics

Residual seminal vesicle displacement in marker-based image-guided radiotherapy for prostate cancer and the impact on margin design.

01-06-2011

Climacteric : the journal of the International Menopause Society

Characteristics of breast cancer patients who experience menopausal transition due to treatment.

01-06-2011

The Journal of pharmacology and experimental therapeutics

P-glycoprotein (ABCB1) transports the primary active tamoxifen metabolites endoxifen and 4-hydroxytamoxifen and restricts their brain penetration.

01-06-2011

Pharmacological reviews

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice.

01-06-2011

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Quality of life and consequences for daily life of familial adenomatous polyposis (FAP) family members.

01-06-2011

Psycho-oncology

Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes.

01-06-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a quantitative assay for the determination of tamoxifen and its five main phase I metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.

01-06-2011

Journal of pharmaceutical and biomedical analysis

Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques.

01-06-2011

Current oncology reports

Non-clear cell renal cell carcinoma: how new biological insight may lead to new therapeutic modalities.

01-06-2011

PLoS biology

Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.

01-06-2011

Genetics in medicine : official journal of the American College of Medical Genetics

Compliance with periodic surveillance for Von-Hippel-Lindau disease.

01-06-2011

Bioconjugate chemistry

Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.

18-05-2011

The EMBO journal

Chromatin: constructing the big picture.

18-05-2011

Cancer

Overall survival and PD-L1 expression in metastasized malignant melanoma.

15-05-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer.

15-05-2011

Human antibodies

The pharmacokinetics of ¹²⁴I-rituximab in patients with rheumatoid arthritis.

12-05-2011

Human antibodies

The pharmacokinetics of ¹³¹I-rituximab in a patient with CD20 positive non-Hodgkin Lymphoma: evaluation of the effect of radioiodination on the biological properties of rituximab.

12-05-2011

Human antibodies

CD20 antigen imaging with ¹²⁴I-rituximab PET/CT in patients with rheumatoid arthritis.

12-05-2011

The EMBO journal

Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.

04-05-2011