Publications

Disease models & mechanisms

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice.

01-05-2011

The Journal of pathology

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

01-05-2011

Drug metabolism and disposition: the biological fate of chemicals

Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics.

01-05-2011

Breast cancer research and treatment

Sentinel node micrometastases in breast cancer do not affect prognosis: a population-based study.

01-05-2011

Annals of oncology : official journal of the European Society for Medical Oncology

The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer.

01-05-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial.

01-05-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays for the quantification of eribulin (E7389) in various biological matrices.

01-05-2011

International journal of radiation oncology, biology, physics

Three-dimensional analysis of recurrence patterns in rectal cancer: the cranial border in hypofractionated preoperative radiotherapy can be lowered.

01-05-2011

The Journal of pathology

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

01-05-2011

PloS one

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

29-04-2011

Cell

A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.

15-04-2011

Journal of the National Cancer Institute

Independent prognostic value of screen detection in invasive breast cancer.

06-04-2011

Proceedings of the National Academy of Sciences of the United States of America

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6.

05-04-2011

Molecular pharmaceutics

Double-transduced MDCKII cells to study human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) interplay in drug transport across the blood-brain barrier.

04-04-2011

DNA repair

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase.

03-04-2011

Journal of analytical toxicology

Determination of platinum originating from carboplatin in human urine and canine excretion products by inductively coupled plasma mass spectrometry.

01-04-2011

BJU international

Diabetes mellitus and health-related quality of life in prostate cancer: 5-year results from the Prostate Cancer Outcomes Study.

01-04-2011

International journal of radiation oncology, biology, physics

Effects of setup errors and shape changes on breast radiotherapy.

01-04-2011

EMBO reports

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.

01-04-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy.

01-04-2011

Annals of oncology : official journal of the European Society for Medical Oncology

The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review.

01-04-2011

Journal of mammary gland biology and neoplasia

Studying therapy response and resistance in mouse models for BRCA1-deficient breast cancer.

01-04-2011

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Questioning the value of (99m)Tc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer.

01-04-2011

Fundamental & clinical pharmacology

Deoxyuridine analog nucleotides in deoxycytidine analog treatment: secondary active metabolites?

01-04-2011

Nederlands tijdschrift voor geneeskunde

[Adult cancer patients are surviving longer in the Netherlands: 5-year survival rate increased by 12% between the periods 1989-1993 and 2004-2008].

31-03-2011

Cancer imaging : the official publication of the International Cancer Imaging Society

Radiofrequency ablation as a treatment tool for liver metastases of colorectal origin.

24-03-2011

Proceedings of the National Academy of Sciences of the United States of America

The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.

15-03-2011

The British journal of surgery

Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer.

01-03-2011

Head & neck

Tumor volume as prognostic factor in chemoradiation for advanced head and neck cancer.

01-03-2011

European journal of cancer (Oxford, England : 1990)

Normative data for the EORTC QLQ-C30 and EORTC-sexuality items in the general Dutch population.

01-03-2011

PLoS genetics

Interactions among Polycomb domains are guided by chromosome architecture.

01-03-2011

Journal of cell science

Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish.

01-03-2011

Nature medicine

Taming the dragon: genomic biomarkers to individualize the treatment of cancer.

01-03-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Magnetic resonance imaging response monitoring of breast cancer during neoadjuvant chemotherapy: relevance of breast cancer subtype.

20-02-2011

PloS one

Functional characterization of human cancer-derived TRKB mutations.

17-02-2011

Cancer cell

A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer.

15-02-2011

PloS one

Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue.

11-02-2011

Epigenetics & chromatin

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.

03-02-2011

Journal of biomedical optics

Tracer-cocktail injections for combined pre- and intraoperative multimodal imaging of lymph nodes in a spontaneous mouse prostate tumor model.

02-02-2011

Archives of dermatology

Impact of melanoma on patients' lives among 562 survivors: a Dutch population-based study.

01-02-2011

Breast cancer research and treatment

Body weight and risk of breast cancer in BRCA1/2 mutation carriers.

01-02-2011

Medical physics

Simplifying EPID dosimetry for IMRT treatment verification.

01-02-2011

Nature structural & molecular biology

Structural basis of substrate discrimination and integrin binding by autotaxin.

01-02-2011

Cell cycle (Georgetown, Tex.)

Screening for modulators of cisplatin sensitivity: unbiased screens reveal common themes.

01-02-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors.

01-02-2011

Plastic and reconstructive surgery

Temporary banking of the nipple-areola complex in 97 skin-sparing mastectomies.

01-02-2011

Psycho-oncology

Psychological distress and quality of life of partners of individuals with familial adenomatous polyposis.

01-02-2011

Genes, chromosomes & cancer

Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors.

01-02-2011

Psycho-oncology

Effectiveness of behavioral techniques and physical exercise on psychosocial functioning and health-related quality of life in breast cancer patients and survivors--a meta-analysis.

01-02-2011

Current clinical pharmacology

Pharmacodynamic biomarkers in model-based drug development in oncology.

01-02-2011