Publications

Molecular cell

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.

07-10-2011

PLoS genetics

A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.

01-10-2011

Current opinion in cell biology

Mechanisms of integrin activation and trafficking.

01-10-2011

European urology

Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer.

01-10-2011

Urology

A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ.

01-10-2011

Investigational new drugs

Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice.

01-10-2011

Journal of analytical toxicology

Determination of sunitinib and its active metabolite N-desethylsunitinib in sweat of a patient.

01-10-2011

Cancer immunology, immunotherapy : CII

Combination of targeted therapy and immunotherapy in melanoma.

01-10-2011

Clinical endocrinology

Health-related quality of life among thyroid cancer survivors: a systematic review.

01-10-2011

International journal of pharmaceutics

Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis.

20-09-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors.

15-09-2011

Nature reviews. Molecular cell biology

Insights into autotaxin: how to produce and present a lipid mediator.

14-09-2011

The EMBO journal

C/EBPβ: lost beyond translation.

14-09-2011

BioEssays : news and reviews in molecular, cellular and developmental biology

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models.

01-09-2011

EMBO reports

Progressive methylation of ageing histones by Dot1 functions as a timer.

01-09-2011

European journal of cancer (Oxford, England : 1990)

The Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship registry: scope, rationale and design of an infrastructure for the study of physical and psychosocial outcomes in cancer survivorship cohorts.

01-09-2011

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A novel method for megavoltage scatter correction in cone-beam CT acquired concurrent with rotational irradiation.

01-09-2011

Annals of hematology

The impact of treatment, socio-demographic and clinical characteristics on health-related quality of life among Hodgkin's and non-Hodgkin's lymphoma survivors: a systematic review.

01-09-2011

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

'Flooding' of the lungs and severe dyspnea in a patient with bronchoalveolar carcinoma.

01-09-2011

Oncogene

Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis.

01-09-2011

The Journal of investigative dermatology

T-cell receptor gene therapy: critical parameters for clinical success.

01-09-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Additional value and potential use of the 70-gene prognosis signature in node-negative breast cancer in daily clinical practice.

01-09-2011

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Review: incidence and clinical significance of Bevacizumab-related non-surgical and surgical serious adverse events in metastatic colorectal cancer.

01-09-2011

Gut

Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer

24-08-2011

Nature cell biology

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

21-08-2011

Oncogene

Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53.

18-08-2011

Chembiochem : a European journal of chemical biology

Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression.

16-08-2011

Human molecular genetics

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

15-08-2011

Nature reviews. Cancer

MicroRNA regulation by RNA-binding proteins and its implications for cancer.

05-08-2011

Human brain mapping

Cerebral hyporesponsiveness and cognitive impairment 10 years after chemotherapy for breast cancer.

01-08-2011

Breast cancer research and treatment

Unfavourable pattern of metastases in M0 breast cancer patients during 1978-2008: a population-based analysis of the Munich Cancer Registry.

01-08-2011

Translational oncology

Immunohistochemical detection of the CXCR4 expression in tumor tissue using the fluorescent peptide antagonist Ac-TZ14011-FITC.

01-08-2011

Drug metabolism and disposition: the biological fate of chemicals

Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.

01-08-2011

Cancer discovery

Functional subtyping of breast cancer.

01-08-2011

Nucleic acids research

Computational identification of insertional mutagenesis targets for cancer gene discovery.

01-08-2011

European journal of cancer (Oxford, England : 1990)

Impact of chemotherapy on health status and symptom burden of colon cancer survivors: a population-based study.

01-08-2011

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

01-08-2011

Journal of structural biology

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.

01-08-2011

Journal of structural biology

Investigating a macromolecular complex: the toolkit of methods.

01-08-2011

International journal of cancer

Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7.

15-07-2011

Journal of medicinal chemistry

Structure-based design of novel boronic acid-based inhibitors of autotaxin.

14-07-2011

J Clin Invest: The Journal of clinical investigation

Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance

11-07-2011

Nucleic acids research

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.

01-07-2011

Clinical pharmacology and therapeutics

Population pharmacokinetic-pharmacodynamic analysis of trastuzumab-associated cardiotoxicity.

01-07-2011

Breast cancer research and treatment

Improved survival of patients with primary distant metastatic breast cancer in the period of 1995-2008. A nationwide population-based study in the Netherlands.

01-07-2011

Annals of oncology : official journal of the European Society for Medical Oncology

An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients.

01-07-2011

The British journal of surgery

Impact of concentration of oesophageal and gastric cardia cancer surgery on long-term population-based survival.

01-07-2011

Cancer cell

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

14-06-2011

The oncologist

Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.

11-06-2011

The oncologist

Part 4: pharmacogenetic variability in anticancer pharmacodynamic drug effects.

11-06-2011