Publications

Cancer treatment reviews

Circulating tumor cells as pharmacodynamic biomarker in early clinical oncological trials.

01-12-2011

Biochemical Society transactions

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.

01-12-2011

Pigment cell & melanoma research

Oncogene-induced senescence and melanoma: where do we stand?

01-12-2011

Journal of cancer research and clinical oncology

Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer.

01-12-2011

International journal of pharmaceutics

Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001).

28-11-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Compromised health-related quality of life in patients with low-grade glioma.

20-11-2011

Nederlands tijdschrift voor geneeskunde

[Measuring quality of life in every oncological patient].

17-11-2011

Nederlands tijdschrift voor geneeskunde

[Issues around melanoma].

17-11-2011

International journal of radiation oncology, biology, physics

Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma.

15-11-2011

The Biochemical journal

Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.

15-11-2011

Hum Mutat: Human mutation

ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

03-11-2011

BMC cancer

A cost-effectiveness analysis of a preventive exercise program for patients with advanced head and neck cancer treated with concomitant chemo-radiotherapy.

03-11-2011

Breast cancer research and treatment

A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients.

01-11-2011

Breast cancer research and treatment

Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups.

01-11-2011

Lung cancer (Amsterdam, Netherlands)

Tubulin, BRCA1, ERCC1, Abraxas, RAP80 mRNA expression, p53/p21 immunohistochemistry and clinical outcome in patients with advanced non small-cell lung cancer receiving first-line platinum-gemcitabine chemotherapy.

01-11-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Phase I evaluation of telatinib, a VEGF receptor tyrosine kinase inhibitor, in combination with bevacizumab in subjects with advanced solid tumors.

01-11-2011

International journal of radiation oncology, biology, physics

Image-guided radiotherapy for breast cancer patients: surgical clips as surrogate for breast excision cavity.

01-11-2011

International journal of radiation oncology, biology, physics

Impact of preoperative radiotherapy on general and disease-specific health status of rectal cancer survivors: a population-based study.

01-11-2011

Breast cancer research : BCR

Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness.

27-10-2011

Nature communications

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.

25-10-2011

PloS one

3'UTR-mediated gene silencing of the Mixed Lineage Leukemia (MLL) gene.

15-10-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry.

15-10-2011

The EMBO journal

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

14-10-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial.

10-10-2011

DNA repair

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

10-10-2011

PloS one

The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.

08-10-2011

Molecular cell

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.

07-10-2011

PLoS genetics

A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.

01-10-2011

Current opinion in cell biology

Mechanisms of integrin activation and trafficking.

01-10-2011

European urology

Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer.

01-10-2011

Urology

A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ.

01-10-2011

Investigational new drugs

Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice.

01-10-2011

Journal of analytical toxicology

Determination of sunitinib and its active metabolite N-desethylsunitinib in sweat of a patient.

01-10-2011

Cancer immunology, immunotherapy : CII

Combination of targeted therapy and immunotherapy in melanoma.

01-10-2011

Clinical endocrinology

Health-related quality of life among thyroid cancer survivors: a systematic review.

01-10-2011

International journal of pharmaceutics

Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis.

20-09-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors.

15-09-2011

Nature reviews. Molecular cell biology

Insights into autotaxin: how to produce and present a lipid mediator.

14-09-2011

The EMBO journal

C/EBPβ: lost beyond translation.

14-09-2011

BioEssays : news and reviews in molecular, cellular and developmental biology

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models.

01-09-2011

EMBO reports

Progressive methylation of ageing histones by Dot1 functions as a timer.

01-09-2011

European journal of cancer (Oxford, England : 1990)

The Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship registry: scope, rationale and design of an infrastructure for the study of physical and psychosocial outcomes in cancer survivorship cohorts.

01-09-2011

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A novel method for megavoltage scatter correction in cone-beam CT acquired concurrent with rotational irradiation.

01-09-2011

Annals of hematology

The impact of treatment, socio-demographic and clinical characteristics on health-related quality of life among Hodgkin's and non-Hodgkin's lymphoma survivors: a systematic review.

01-09-2011

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

'Flooding' of the lungs and severe dyspnea in a patient with bronchoalveolar carcinoma.

01-09-2011

Oncogene

Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis.

01-09-2011

The Journal of investigative dermatology

T-cell receptor gene therapy: critical parameters for clinical success.

01-09-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Additional value and potential use of the 70-gene prognosis signature in node-negative breast cancer in daily clinical practice.

01-09-2011

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Review: incidence and clinical significance of Bevacizumab-related non-surgical and surgical serious adverse events in metastatic colorectal cancer.

01-09-2011

Gut

Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer

24-08-2011