Publications

British journal of cancer

A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.

07-06-2011

The oncologist

Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.

03-06-2011

The oncologist

Part 1: background, methodology, and clinical adoption of pharmacogenetics.

03-06-2011

The oncologist

Trastuzumab.

03-06-2011

The AAPS journal

Evaluation of α2-integrin expression as a biomarker for tumor growth inhibition for the investigational integrin inhibitor E7820 in preclinical and clinical studies.

01-06-2011

International journal of radiation oncology, biology, physics

Residual seminal vesicle displacement in marker-based image-guided radiotherapy for prostate cancer and the impact on margin design.

01-06-2011

Climacteric : the journal of the International Menopause Society

Characteristics of breast cancer patients who experience menopausal transition due to treatment.

01-06-2011

The Journal of pharmacology and experimental therapeutics

P-glycoprotein (ABCB1) transports the primary active tamoxifen metabolites endoxifen and 4-hydroxytamoxifen and restricts their brain penetration.

01-06-2011

Pharmacological reviews

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice.

01-06-2011

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Quality of life and consequences for daily life of familial adenomatous polyposis (FAP) family members.

01-06-2011

Psycho-oncology

Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes.

01-06-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a quantitative assay for the determination of tamoxifen and its five main phase I metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.

01-06-2011

Journal of pharmaceutical and biomedical analysis

Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques.

01-06-2011

Current oncology reports

Non-clear cell renal cell carcinoma: how new biological insight may lead to new therapeutic modalities.

01-06-2011

PLoS biology

Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.

01-06-2011

Genetics in medicine : official journal of the American College of Medical Genetics

Compliance with periodic surveillance for Von-Hippel-Lindau disease.

01-06-2011

Bioconjugate chemistry

Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.

18-05-2011

The EMBO journal

Chromatin: constructing the big picture.

18-05-2011

Cancer

Overall survival and PD-L1 expression in metastasized malignant melanoma.

15-05-2011

Clinical cancer research : an official journal of the American Association for Cancer Research

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer.

15-05-2011

Human antibodies

The pharmacokinetics of ¹²⁴I-rituximab in patients with rheumatoid arthritis.

12-05-2011

Human antibodies

The pharmacokinetics of ¹³¹I-rituximab in a patient with CD20 positive non-Hodgkin Lymphoma: evaluation of the effect of radioiodination on the biological properties of rituximab.

12-05-2011

Human antibodies

CD20 antigen imaging with ¹²⁴I-rituximab PET/CT in patients with rheumatoid arthritis.

12-05-2011

The EMBO journal

Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence.

04-05-2011

Tumori

Serum beta-HCG and CA-125 as tumor markers in a patient with osteosarcoma: case report.

03-05-2011

Disease models & mechanisms

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice.

01-05-2011

The Journal of pathology

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

01-05-2011

Drug metabolism and disposition: the biological fate of chemicals

Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics.

01-05-2011

Breast cancer research and treatment

Sentinel node micrometastases in breast cancer do not affect prognosis: a population-based study.

01-05-2011

Annals of oncology : official journal of the European Society for Medical Oncology

The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer.

01-05-2011

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial.

01-05-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays for the quantification of eribulin (E7389) in various biological matrices.

01-05-2011

International journal of radiation oncology, biology, physics

Three-dimensional analysis of recurrence patterns in rectal cancer: the cranial border in hypofractionated preoperative radiotherapy can be lowered.

01-05-2011

The Journal of pathology

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

01-05-2011

PloS one

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

29-04-2011

Cell

A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.

15-04-2011

Journal of the National Cancer Institute

Independent prognostic value of screen detection in invasive breast cancer.

06-04-2011

Proceedings of the National Academy of Sciences of the United States of America

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6.

05-04-2011

Molecular pharmaceutics

Double-transduced MDCKII cells to study human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) interplay in drug transport across the blood-brain barrier.

04-04-2011

DNA repair

HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase.

03-04-2011

Journal of analytical toxicology

Determination of platinum originating from carboplatin in human urine and canine excretion products by inductively coupled plasma mass spectrometry.

01-04-2011

BJU international

Diabetes mellitus and health-related quality of life in prostate cancer: 5-year results from the Prostate Cancer Outcomes Study.

01-04-2011

International journal of radiation oncology, biology, physics

Effects of setup errors and shape changes on breast radiotherapy.

01-04-2011

EMBO reports

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.

01-04-2011

Annals of oncology : official journal of the European Society for Medical Oncology

Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy.

01-04-2011

Annals of oncology : official journal of the European Society for Medical Oncology

The relation between information provision and health-related quality of life, anxiety and depression among cancer survivors: a systematic review.

01-04-2011

Journal of mammary gland biology and neoplasia

Studying therapy response and resistance in mouse models for BRCA1-deficient breast cancer.

01-04-2011

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Questioning the value of (99m)Tc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer.

01-04-2011

Fundamental & clinical pharmacology

Deoxyuridine analog nucleotides in deoxycytidine analog treatment: secondary active metabolites?

01-04-2011

Nederlands tijdschrift voor geneeskunde

[Adult cancer patients are surviving longer in the Netherlands: 5-year survival rate increased by 12% between the periods 1989-1993 and 2004-2008].

31-03-2011