Publications

European journal of immunology

Reduced tumor-antigen density leads to PD-1/PD-L1-mediated impairment of partially exhausted CD8⁺ T cells.

01-03-2012

Future oncology (London, England)

Optical spectroscopy: current advances and future applications in cancer diagnostics and therapy.

01-03-2012

Current opinion in urology

Fluorescence guidance in urologic surgery.

01-03-2012

Journal of clinical pharmacology

From mouse to man: predictions of human pharmacokinetics of orally administered docetaxel from preclinical studies.

01-03-2012

Nucleus (Austin, Tex.)

Hox in space: gene cluster regulation linked to folding of chromatin.

01-03-2012

Mol Cell Proteomics: Molecular & cellular proteomics: MCP

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer

24-02-2012

Nature

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.

22-02-2012

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Drug resistance in the mouse cancer clinic.

18-02-2012

Breast cancer research and treatment

Neoadjuvant chemotherapy in ER+ HER2- breast cancer: response prediction based on immunohistochemical and molecular characteristics.

01-02-2012

Trends in pharmacological sciences

Functions of OATP1A and 1B transporters in vivo: insights from mouse models.

01-02-2012

Epigenomics

Crosstalk between aging and the epigenome.

01-02-2012

The Journal of clinical investigation

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

01-02-2012

Journal of clinical pharmacology

Model-based evaluation of similarity in pharmacokinetics of two formulations of the blood-derived plasma product c1 esterase inhibitor.

01-02-2012

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Integration of a smoking cessation program in the treatment protocol for patients with head and neck and lung cancer.

01-02-2012

Breast cancer research and treatment

Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs.

01-02-2012

Lung cancer (Amsterdam, Netherlands)

Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis.

01-02-2012

Current opinion in genetics & development

Using genetically engineered mouse models to validate candidate cancer genes and test new therapeutic approaches.

01-02-2012

Drug metabolism and disposition: the biological fate of chemicals

Mass balance study of [¹⁴C]eribulin in patients with advanced solid tumors.

01-02-2012

Nature

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

26-01-2012

Journal of cell science

Dynamics within tetraspanin pairs affect MHC class II expression.

15-01-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remission.

10-01-2012

Cellular and molecular life sciences : CMLS

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

01-01-2012

Biomaterials

Targeted non-covalent self-assembled nanoparticles based on human serum albumin.

01-01-2012

Cancer chemotherapy and pharmacology

Gene polymorphisms, pharmacokinetics, and hematological toxicity in advanced non-small-cell lung cancer patients receiving cisplatin/gemcitabine.

01-01-2012

The Journal of clinical investigation

Blood pressure influences end-stage renal disease of Cd151 knockout mice.

01-01-2012

International journal of cancer

Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.

01-01-2012

Journal of clinical laboratory analysis

Search for breast cancer biomarkers in fractionated serum samples by protein profiling with SELDI-TOF MS.

01-01-2012

Journal of affective disorders

Type D (distressed) personality is associated with poor quality of life and mental health among 3080 cancer survivors.

01-01-2012

Medical physics

In aqua vivo EPID dosimetry.

01-01-2012

The Journal of pathology

Fancf-deficient mice are prone to develop ovarian tumours.

01-01-2012

Results in immunology

Testing for HLA/peptide tetramer-binding to the T cell receptor complex on human T lymphocytes.

01-01-2012

Pharmacoepidemiology and drug safety

Record linkage for pharmacoepidemiological studies in cancer patients.

01-01-2012

Cell cycle (Georgetown, Tex.)

News about old histones: a role for histone age in controlling the epigenome.

01-01-2012

Breast cancer research and treatment

Head-to-head comparison of the 70-gene signature versus the 21-gene assay: cost-effectiveness and the effect of compliance.

01-01-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Genetic variants in TGFβ-1 and PAI-1 as possible risk factors for cardiovascular disease after radiotherapy for breast cancer.

01-01-2012

PloS one

LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor.

24-12-2011

Chemistry & biology

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

23-12-2011

The Journal of experimental medicine

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.

19-12-2011

Bioinformatics (Oxford, England)

Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank.

15-12-2011

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenates.

15-12-2011

Cancer cell

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

13-12-2011

Molecular pharmaceutics

Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.

05-12-2011

Trials

The impact of a cancer Survivorship Care Plan on gynecological cancer patient and health care provider reported outcomes (ROGY Care): study protocol for a pragmatic cluster randomized controlled trial.

05-12-2011

Lancet (London, England)

Tilting the AXIS towards therapeutic limits in renal cancer.

03-12-2011

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Suffering in long-term cancer survivors: an evaluation of the PRISM-R2 in a population-based cohort.

01-12-2011

Melanoma research

Expression of the embryological morphogen Nodal in stage III/IV melanoma.

01-12-2011

Human reproduction (Oxford, England)

Risk of borderline and invasive ovarian tumours after ovarian stimulation for in vitro fertilization in a large Dutch cohort.

01-12-2011

Journal of clinical epidemiology

Validation study suggested no differential misclassification of self-reported mammography history in BRCA1/2 mutation carriers.

01-12-2011

Bioanalysis

Bioanalytical aspects of clinical mass balance studies in oncology.

01-12-2011

Genome research

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

01-12-2011