Publications

Psycho-oncology

Information about chemotherapy-associated cognitive problems contributes to cognitive problems in cancer patients.

01-10-2012

Gynecologic oncology

Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study.

01-10-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004).

01-10-2012

Clinical cancer research : an official journal of the American Association for Cancer Research

Alternative cleavage and polyadenylation during colorectal cancer development.

01-10-2012

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Understanding resistance to targeted cancer drugs through loss of function genetic screens.

01-10-2012

European journal of haematology

Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry.

01-10-2012

Annals of hematology

Perceived information provision and satisfaction among lymphoma and multiple myeloma survivors--results from a Dutch population-based study.

01-10-2012

Patient education and counseling

Breast cancer genetic counseling after diagnosis but before treatment: a pilot study on treatment consequences and psychological impact.

01-10-2012

Bioinformatics (Oxford, England)

A regression model for estimating DNA copy number applied to capture sequencing data.

15-09-2012

Cell

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.

14-09-2012

The EMBO journal

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

12-09-2012

Cancer cell

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.

11-09-2012

Current biology : CB

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

11-09-2012

BMJ (Clinical research ed.)

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).

06-09-2012

Molecular pharmaceutics

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

04-09-2012

The American journal of pathology

Targeting BRAFV600E in an inducible murine model of melanoma.

01-09-2012

Journal of cell science

The emerging role of Polycomb repressors in the response to DNA damage.

01-09-2012

Nature reviews. Clinical oncology

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

01-09-2012

Nature reviews. Cancer

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.

01-09-2012

Journal of cellular and molecular medicine

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.

01-09-2012

Cancer causes & control : CCC

Most colorectal cancer survivors live a large proportion of their remaining life in good health.

01-09-2012

The AAPS journal

Performance of methods for handling missing categorical covariate data in population pharmacokinetic analyses.

01-09-2012

Familial cancer

Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance.

01-09-2012

European journal of cancer (Oxford, England : 1990)

Socio-economic implications of cancer survivorship: results from the PROFILES registry.

01-09-2012

Patient education and counseling

Endometrial cancer survivors are unsatisfied with received information about diagnosis, treatment and follow-up: a study from the population-based PROFILES registry.

01-09-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical correlates of 'BRCAness' in triple-negative breast cancer of patients receiving adjuvant chemotherapy.

01-09-2012

Journal of gastroenterology

Excess weight among colorectal cancer survivors: target for intervention.

01-09-2012

Cell

Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.

31-08-2012

Sub-cellular biochemistry

Cdt1 and geminin in DNA replication initiation.

25-08-2012

Oncogene

Targeting the epigenome for treatment of cancer.

23-08-2012

BMC research notes

Scenario drafting to anticipate future developments in technology assessment.

16-08-2012

Journal of the American Chemical Society

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

15-08-2012

Cell death & disease

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.

09-08-2012

Annals of oncology : official journal of the European Society for Medical Oncology

The Dutch Childhood Oncology Group guideline for follow-up of asymptomatic cardiac dysfunction in childhood cancer survivors.

01-08-2012

Investigational new drugs

Two-stage model-based design of cancer phase I dose escalation trials: evaluation using the phase I program of barasertib (AZD1152).

01-08-2012

Cancer prevention research (Philadelphia, Pa.)

Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.

01-08-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Impact of negative margin width on local recurrence in breast conserving therapy.

01-08-2012

Journal of cancer research and clinical oncology

Chemotherapy as primary treatment for brain metastases from breast cancer: analysis of 115 one-year survivors.

01-08-2012

Breast (Edinburgh, Scotland)

Axillary and systemic treatment of patients with breast cancer and micrometastatic disease or isolated tumor cells in the sentinel lymph node.

01-08-2012

Oncoimmunology

Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

01-08-2012

British journal of clinical pharmacology

Model-based treatment optimization of a novel VEGFR inhibitor.

01-08-2012

Investigational new drugs

Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.

01-08-2012

Diabetologia

Disease-specific mortality among stage I-III colorectal cancer patients with diabetes: a large population-based analysis.

01-08-2012

BMC health services research

Exploring improvements in patient logistics in Dutch hospitals with a survey.

01-08-2012

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular-signal-regulated kinase and DNA in circulating tumor cells.

01-08-2012

PLoS genetics

A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.

19-07-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection.

15-07-2012

The Journal of biological chemistry

Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

06-07-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Pre-treatment imaging and pathology characteristics of invasive breast cancers of limited extent: potential relevance for MRI-guided localized therapy.

01-07-2012

Oncoimmunology

TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.

01-07-2012