Publications

Oncogene

Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent.

01-05-2014

Cancer immunology, immunotherapy : CII

Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma.

01-05-2014

Lasers in medical science

Optical biopsy of epithelial cancers by optical coherence tomography (OCT).

01-05-2014

Oncogene

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.

24-04-2014

Physics in medicine and biology

Automatic detection system for multiple region of interest registration to account for posture changes in head and neck radiotherapy.

21-04-2014

Nature

Domains of genome-wide gene expression dysregulation in Down's syndrome.

17-04-2014

Current biology : CB

Dopaminergic modulation of cAMP drives nonlinear plasticity across the Drosophila mushroom body lobes.

14-04-2014

Nucleus (Austin, Tex.)

Stochastic genome-nuclear lamina interactions: modulating roles of Lamin A and BAF.

11-04-2014

Oncogene

Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides.

10-04-2014

Cell reports

Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.

10-04-2014

Cell reports

Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.

10-04-2014

Methods in molecular biology (Clifton, N.J.)

Intradermal vaccination by DNA tattooing.

10-04-2014

Nature

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.

03-04-2014

The Lancet. Oncology

Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study.

01-04-2014

PLoS genetics

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

01-04-2014

Journal of the International Neuropsychological Society : JINS

Systemically treated breast cancer patients and controls: an evaluation of the presence of noncredible performance.

01-04-2014

Clinical pharmacokinetics

Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.

01-04-2014

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the light sensitive survivin suppressant sepantronium bromide (YM155) in mouse plasma.

01-04-2014

Journal of genetic counseling

Specific psychosocial issues of individuals undergoing genetic counseling for cancer - a literature review.

01-04-2014

PLoS genetics

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.

01-04-2014

European journal of epidemiology

Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study.

01-04-2014

Annals of oncology : official journal of the European Society for Medical Oncology

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

01-04-2014

Trends in immunology

Single cell behavior in T cell differentiation.

01-04-2014

Nature structural & molecular biology

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

01-04-2014

Clinical pharmacology and therapeutics

Herb-drug interactions in oncology.

01-04-2014

Cancer biology & therapy

Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy.

01-04-2014

Annals of surgical oncology

The prognostic significance of an R1 resection in gastric cancer patients treated with adjuvant chemoradiotherapy.

01-04-2014

Diabetes & metabolism

Colorectal cancer, diabetes and survival: epidemiological insights.

01-04-2014

Translational oncology

Monitoring of tumor response to Cisplatin using optical spectroscopy.

01-04-2014

Proceedings of the National Academy of Sciences of the United States of America

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

01-04-2014

Bioanalysis

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

01-04-2014

Cancer discovery

Unlikely suspects identified in neuroblastoma conspiracy.

01-04-2014

The Lancet. Oncology

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

01-04-2014

PLoS genetics

Chromatin landscapes of retroviral and transposon integration profiles.

01-04-2014

European journal of cancer (Oxford, England : 1990)

Risk estimations and treatment decisions in early stage breast cancer: agreement among oncologists and the impact of the 70-gene signature.

01-04-2014

BioMed research international

Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy.

29-03-2014

Molecular cell

Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.

20-03-2014

International journal of cancer

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

15-03-2014

Molecular cell

Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition.

06-03-2014

Nature

Cancer: Inflammation lights the way to metastasis.

06-03-2014

Human brain mapping

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.

01-03-2014

European journal of cancer (Oxford, England : 1990)

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983.

01-03-2014

Cancer letters

Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.

01-03-2014

The Lancet. Oncology

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study.

01-03-2014

Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

01-03-2014

European urology

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.

01-03-2014

Clinical pharmacokinetics

Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study.

01-03-2014

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Association between metformin use and mortality in patients with prostate cancer: explained by confounding by indication?

01-03-2014

Molecular pharmacology

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

01-03-2014

Medical physics

Multi-institutional dosimetric and geometric commissioning of image-guided small animal irradiators.

01-03-2014