Publications

European journal of endocrinology

Surgery for adrenocortical carcinoma in The Netherlands: analysis of the national cancer registry data.

01-07-2013

British journal of clinical pharmacology

Optimizing drug development of anti-cancer drugs in children using modelling and simulation.

01-07-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical treatment results of intestinal and diffuse type gastric cancer. Implications for a differentiated therapeutic approach?

01-07-2013

Nature reviews. Genetics

Alternative cleavage and polyadenylation: extent, regulation and function.

01-07-2013

PloS one

Kindlin-1 regulates integrin dynamics and adhesion turnover.

19-06-2013

Nucleic Acids Res.

Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

14-06-2013

Scientific reports

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance.

07-06-2013

Nature

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

06-06-2013

Cancer Research

Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling

03-06-2013

Nat Commun.: Nature communications

ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets

01-06-2013

Breast cancer research and treatment

CYP2C19 2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen and no systemic treatment.

01-06-2013

Psycho-oncology

Assessing the impact of cancer among Dutch non-Hodgkin lymphoma survivors compared with their American counterparts: a cross-national study.

01-06-2013

Familial cancer

100 years Lynch syndrome: what have we learned about psychosocial issues?

01-06-2013

Cancer

Population-based cancer registries for quality-of-life research: a work-in-progress resource for survivorship studies?

01-06-2013

Antimicrobial agents and chemotherapy

Severe skin toxicity in pediatric oncology patients treated with voriconazole and concomitant methotrexate.

01-06-2013

Cancer treatment reviews

Is combination therapy the next step to overcome resistance and reduce toxicities in melanoma?

01-06-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local dose-effect relations for lung perfusion post stereotactic body radiotherapy.

01-06-2013

Oral oncology

Can extranodal spread in head and neck cancer be detected on MR imaging.

01-06-2013

Cancer

The role of comprehensive cancer centers in survivorship care.

01-06-2013

Clinical pharmacokinetics

Oral anticancer drugs: mechanisms of low bioavailability and strategies for improvement.

01-06-2013

Breast cancer research and treatment

Platform comparisons for identification of breast cancers with a BRCA-like copy number profile.

01-06-2013

Drug delivery and translational research

Pharmacokinetic evaluation of three oral formulations of docetaxel boosted with ritonavir: two single-drug formulations vs. a fixed-dose combination tablet.

01-06-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognostic parameters for acute esophagus toxicity in intensity modulated radiotherapy and concurrent chemotherapy for locally advanced non-small cell lung cancer.

01-06-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Vemurafenib as neoadjuvant treatment for unresectable regional metastatic melanoma.

01-06-2013

Nature communications

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.

30-05-2013

The EMBO journal

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.

29-05-2013

British journal of cancer

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers.

28-05-2013

Nature communications

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

23-05-2013

PloS one

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

22-05-2013

PloS one

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

22-05-2013

The breast journal

Paclitaxel, carboplatin, and trastuzumab in a neo-adjuvant regimen for HER2-positive breast cancer.

21-05-2013

The oncologist

Concise drug review: azacitidine and decitabine.

15-05-2013

The breast journal

Major changes in chemotherapy regimens administered to breast cancer patients during 2000-2008 in the Netherlands.

15-05-2013

International journal of cancer

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.

15-05-2013

Cancer cell

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

13-05-2013

Nederlands tijdschrift voor geneeskunde

[Concomitant use of proton pump inhibitors and systemic corticosteroids].

10-05-2013

Proc Natl Acad Sci U S A: Proceedings of the National Academy of Siences of the United States of America

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

08-05-2013

Science (New York, N.Y.)

Heterogeneous differentiation patterns of individual CD8+ T cells.

03-05-2013

The Journal of urology

FDG-positron emission tomography/computerized tomography for monitoring the response of pelvic lymph node metastasis to neoadjuvant chemotherapy for bladder cancer.

01-05-2013

International journal of radiation oncology, biology, physics

Hybrid registration of prostate and seminal vesicles for image guided radiation therapy.

01-05-2013

Gynecologic oncology

Follow-up practice in endometrial cancer and the association with patient and hospital characteristics: a study from the population-based PROFILES registry.

01-05-2013

CNS oncology

Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.

01-05-2013

European journal of cancer (Oxford, England : 1990)

Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo.

01-05-2013

Molecular pharmacology

Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.

01-05-2013

Lung cancer (Amsterdam, Netherlands)

Improved identification of peripheral lung tumors by using diffuse reflectance and fluorescence spectroscopy.

01-05-2013

Journal of cell science

UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway.

01-05-2013

European journal of cancer (Oxford, England : 1990)

Quantifying fatigue in (long-term) colorectal cancer survivors: a study from the population-based patient reported outcomes following initial treatment and long term evaluation of survivorship registry.

01-05-2013

Communicative & integrative biology

Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.

01-05-2013

Nucleic acids research

A scale-space method for detecting recurrent DNA copy number changes with analytical false discovery rate control.

01-05-2013

Science (New York, N.Y.)

Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

26-04-2013