Publications

Immunity

Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape.

20-03-2018

Journal of pharmaceutical and biomedical analysis

Ultra-sensitive LC-MS/MS method for the quantification of gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma for a microdose clinical trial.

20-03-2018

Immunity

Regulation and Function of the PD-L1 Checkpoint.

20-03-2018

British journal of cancer

High burden of subsequent malignant neoplasms and cardiovascular disease in long-term Hodgkin lymphoma survivors.

20-03-2018

Nature communications

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

19-03-2018

Nature communications

SUMO targets the APC/C to regulate transition from metaphase to anaphase.

16-03-2018

The Journal of cell biology

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

05-03-2018

Molecular systems biology

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

05-03-2018

Oncotarget

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors.

02-03-2018

JAMA oncology.

Breast implants and the risk of anaplastic large cell lymphoma in the breast.

01-03-2018

Head & neck

Androgen deprivation therapy for androgen receptor-positive advanced salivary duct carcinoma: A nationwide case series of 35 patients in The Netherlands.

01-03-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Monitoring early changes in rectal tumor morphology and volume during 5 weeks of preoperative chemoradiotherapy - An evaluation with sequential MRIs.

01-03-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Improved pharmacodynamic (PD) assessment of low dose PARP inhibitor PD activity for radiotherapy and chemotherapy combination trials.

01-03-2018

Radiologic clinics of North America

Role of Prostate MR Imaging in Radiation Oncology.

01-03-2018

Lasers in surgery and medicine

Nerve detection using optical spectroscopy, an evaluation in four different models: In human and swine, in-vivo, and post mortem.

01-03-2018

Oncogene

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance.

01-03-2018

Clinical rehabilitation

Feasibility of a home-based exercise intervention with remote guidance for patients with stable grade II and III gliomas: a pilot randomized controlled trial.

01-03-2018

Genetic testing and molecular biomarkers

Patients' Attitudes Towards the Return of Incidental Findings After Research with Residual Tissue: A Mixed Methods Study.

01-03-2018

Protein science : a publication of the Protein Society

Homology-based hydrogen bond information improves crystallographic structures in the PDB.

01-03-2018

JAMA oncology

Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast.

01-03-2018

Journal of neuro-oncology

EpCAM-based assays for epithelial tumor cell detection in cerebrospinal fluid.

01-03-2018

Magnetic resonance in medicine

Performance of a fast and high-resolution multi-echo spin-echo sequence for prostate T₂ mapping across multiple systems.

01-03-2018

Current opinion in urology

Computer-assisted surgery: virtual- and augmented-reality displays for navigation during urological interventions.

01-03-2018

European urology

Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens.

01-03-2018

Oral oncology

Baseline peripheral blood leukocytosis: Biological marker predicts outcome in oropharyngeal cancer, regardless of HPV-status.

01-03-2018

Bioinformatics (Oxford, England)

Bayesian data integration for quantifying the contribution of diverse measurements to parameter estimates.

01-03-2018

Gut

Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment.

01-03-2018

Pharmacological research

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.

01-03-2018

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Recurrent Cancer Is Associated With Dissatisfaction With Care-A Longitudinal Analysis Among Ovarian and Endometrial Cancer Patients.

01-03-2018

BJU international

The accuracy of patients' perceptions of the risks associated with localised prostate cancer treatments.

01-03-2018

Cancer metastasis reviews

Long non-coding RNAs in metastasis.

01-03-2018

Diseases of the colon and rectum

A Pattern-Based Approach Combining Tumor Morphology on MRI With Distinct Signal Patterns on Diffusion-Weighted Imaging to Assess Response of Rectal Tumors After Chemoradiotherapy.

01-03-2018

Toxicology in vitro : an international journal published in association with BIBRA

Drug toxicity profiling of a Saccharomyces cerevisiae deubiquitinase deletion panel shows that acetaminophen mimics tyrosine.

01-03-2018

Nature communications

FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

28-02-2018

BMC cancer

The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors.

27-02-2018

Lancet (London, England)

Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.

24-02-2018

Nature

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

22-02-2018

PLOS one

Improving stability of prediction models based on correlated omics data by using network approaches

20-02-2018

Cancer cell

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

12-02-2018

BMC health services research

Implementing large scale fast track diagnostics in a comprehensive cancer center, pre- and post-measurement data.

07-02-2018

Acta dermato-venereologica

Development and Validation of the Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) Questionnaire.

07-02-2018

Cell reports

BUB1 Is Essential for the Viability of Human Cells in which the Spindle Assembly Checkpoint Is Compromised.

06-02-2018

BMJ open

Cohort profile: LIFEWORK, a prospective cohort study on occupational and environmental risk factors and health in the Netherlands.

03-02-2018

Scientific reports

Author Correction: Deep Learning for Fully-Automated Localization and Segmentation of Rectal Cancer on Multiparametric MR.

02-02-2018

Wellcome open research

Using mitoribosomal profiling to investigate human mitochondrial translation.

02-02-2018

Nature communications

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.

02-02-2018

Science (New York, N.Y.)

Enhancing responses to cancer immunotherapy.

02-02-2018

ESMO open

Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management.

02-02-2018

Nature protocols

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

01-02-2018

Clinical radiology

Diagnostic performance of gadofosveset-enhanced axillary MRI for nodal (re)staging in breast cancer patients: results of a validation study.

01-02-2018