Publications

Melanoma research

Vemurafenib in BRAF-mutant metastatic melanoma patients in real-world clinical practice: prognostic factors associated with clinical outcomes.

01-08-2018

Cancer research

Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines.

01-08-2018

Annals of oncology : official journal of the European Society for Medical Oncology

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma.

01-08-2018

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Clinical lymph node staging in colorectal cancer; a flip of the coin?

01-08-2018

Molecular oncology

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

01-08-2018

Clinical breast cancer

Tumor Resection Margin Definitions in Breast-Conserving Surgery: Systematic Review and Meta-analysis of the Current Literature.

01-08-2018

Psycho-oncology

Association between information provision and supportive care needs among ovarian cancer survivors: A cross-sectional study from the PROFILES registry.

01-08-2018

Frontiers of medicine

Taking advantage of drug resistance, a new approach in the war on cancer.

01-08-2018

Nature cell biology

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

01-08-2018

HPB : the official journal of the International Hepato Pancreato Biliary Association

Myosteatosis predicts survival after surgery for periampullary cancer: a novel method using MRI.

01-08-2018

Journal of structural biology

Baculovirus-driven protein expression in insect cells: A benchmarking study.

01-08-2018

Scandinavian journal of gastroenterology

The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.

01-08-2018

The Journal of antimicrobial chemotherapy

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships.

01-08-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

A systematic review of the measurement properties of the European Organisation for Research and Treatment of Cancer In-patient Satisfaction with Care Questionnaire, the EORTC IN-PATSAT32.

01-08-2018

Journal of sex & marital therapy

Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy.

25-07-2018

BMC cancer

Mitotic count can predict tamoxifen benefit in postmenopausal breast cancer patients while Ki67 score cannot.

24-07-2018

Sarcoma

Outcome of Nonsurgical Management of Extra-Abdominal, Trunk, and Abdominal Wall Desmoid-Type Fibromatosis: A Population-Based Study in the Netherlands.

24-07-2018

Marine drugs

Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment.

23-07-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Risk, Risk Factors, and Surveillance of Subsequent Malignant Neoplasms in Survivors of Childhood Cancer: A Review.

20-07-2018

Nature communications

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.

19-07-2018

ESMO open

Questions asked in the everyday practice: immune checkpoint inhibitors.

19-07-2018

Scientific reports

Buparlisib is a brain penetrable pan-PI3K inhibitor.

17-07-2018

Cancer

More frequent use of health care services among distressed compared with nondistressed survivors of lymphoma and chronic lymphocytic leukemia: Results from the population-based PROFILES registry.

15-07-2018

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry.

15-07-2018

J Clin Oncol.

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era

10-07-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

10-07-2018

Journal of cell science

Chromosomes trapped in micronuclei are liable to segregation errors.

09-07-2018

Nederlands tijdschrift voor geneeskunde

[Freud and colorectal cancer guideline adherence in the Netherlands].

05-07-2018

Cell reports

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development.

03-07-2018

Epigenetics & chromatin

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

03-07-2018

ImmunoHorizons

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

02-07-2018

Nature medicine

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

01-07-2018

Urologic oncology

Mechanistic target of rapamycin (MTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.

01-07-2018

Journal of the National Cancer Institute

Colorectal Adenomas and Cancers After Childhood Cancer Treatment: A DCOG-LATER Record Linkage Study.

01-07-2018

Contact dermatitis

Palladium-induced granulomas analysed with inductively coupled plasma mass spectrometry.

01-07-2018

Cell research

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

01-07-2018

Anti-cancer drugs

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands.

01-07-2018

Cancer immunology research

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4⁺ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.

01-07-2018

Cancer prevention research (Philadelphia, Pa.)

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

01-07-2018

Neoplasia (New York, N.Y.)

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

01-07-2018

Nature medicine

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

01-07-2018

Physics and imaging in radiation oncology

Biochemical recurrence prediction after radiotherapy for prostate cancer with T2w magnetic resonance imaging radiomic features.

01-07-2018

The European journal of health economics : HEPAC : health economics in prevention and care

Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.

01-07-2018

PLoS biology

Decoding the chromatin proteome of a single genomic locus by DNA sequencing.

01-07-2018

The Lancet. Oncology

Adjuvant therapy in resectable gastric cancer-the CRITICS trial - Authors' reply.

01-07-2018

Annals of surgery

Response to: "DCIS and Breast Cancer: Challenging the Paradigm".

01-07-2018

Drug and alcohol dependence

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use.

01-07-2018

Nature cell biology

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

01-07-2018

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?

01-07-2018

Arteriosclerosis, thrombosis, and vascular biology

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

01-07-2018

Vemurafenib in BRAF-mutant metastatic melanoma patients in real-world clinical practice: prognostic factors associated with clinical outcomes.

Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines.

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma.

Clinical lymph node staging in colorectal cancer; a flip of the coin?

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

Tumor Resection Margin Definitions in Breast-Conserving Surgery: Systematic Review and Meta-analysis of the Current Literature.

Association between information provision and supportive care needs among ovarian cancer survivors: A cross-sectional study from the PROFILES registry.

Taking advantage of drug resistance, a new approach in the war on cancer.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

Myosteatosis predicts survival after surgery for periampullary cancer: a novel method using MRI.

Baculovirus-driven protein expression in insect cells: A benchmarking study.

The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships.

A systematic review of the measurement properties of the European Organisation for Research and Treatment of Cancer In-patient Satisfaction with Care Questionnaire, the EORTC IN-PATSAT32.

Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy.

Mitotic count can predict tamoxifen benefit in postmenopausal breast cancer patients while Ki67 score cannot.

Outcome of Nonsurgical Management of Extra-Abdominal, Trunk, and Abdominal Wall Desmoid-Type Fibromatosis: A Population-Based Study in the Netherlands.

Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment.

Risk, Risk Factors, and Surveillance of Subsequent Malignant Neoplasms in Survivors of Childhood Cancer: A Review.

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.

Questions asked in the everyday practice: immune checkpoint inhibitors.

Buparlisib is a brain penetrable pan-PI3K inhibitor.

More frequent use of health care services among distressed compared with nondistressed survivors of lymphoma and chronic lymphocytic leukemia: Results from the population-based PROFILES registry.

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry.

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

Chromosomes trapped in micronuclei are liable to segregation errors.

[Freud and colorectal cancer guideline adherence in the Netherlands].

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development.

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

Mechanistic target of rapamycin (MTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.

Colorectal Adenomas and Cancers After Childhood Cancer Treatment: A DCOG-LATER Record Linkage Study.

Palladium-induced granulomas analysed with inductively coupled plasma mass spectrometry.

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands.

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4+ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

Biochemical recurrence prediction after radiotherapy for prostate cancer with T2w magnetic resonance imaging radiomic features.

Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.

Decoding the chromatin proteome of a single genomic locus by DNA sequencing.

Adjuvant therapy in resectable gastric cancer-the CRITICS trial - Authors' reply.

Response to: "DCIS and Breast Cancer: Challenging the Paradigm".

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use.

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

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Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4⁺ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.