Publications

PloS one

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association.

09-11-2018

The New England journal of medicine

Sunitinib Alone or after Nephrectomy in Renal Cancer.

08-11-2018

Science translational medicine

Enhanced detection of circulating tumor DNA by fragment size analysis.

07-11-2018

BMC cancer

(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors: design of the PABLO trial.

06-11-2018

Molecular pharmaceutics

ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461.

05-11-2018

Journal of cell science

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.

05-11-2018

Molecular pharmaceutics

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability.

05-11-2018

The Journal of cell biology

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler.

05-11-2018

Nucleic acids research

A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression.

02-11-2018

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Multispectral-Fluorescence Imaging as a Tool to Separate Healthy from Disease-Related Lymphatic Anatomy During Robot-Assisted Laparoscopy.

01-11-2018

Nature

Protocadherin-1 is essential for cell entry by New World hantaviruses.

01-11-2018

Cancer letters

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.

01-11-2018

Molecular oncology

European Academy of Cancer Sciences - position paper.

01-11-2018

Nature medicine

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

01-11-2018

The Journal of pathology

Consensus molecular subtype classification of colorectal adenomas.

01-11-2018

Annals of oncology : official journal of the European Society for Medical Oncology

Starting the fight in the tumor: expert recommendations for the development of human intratumoral immunotherapy (HIT-IT).

01-11-2018

Endocrine-related cancer

Molecular underpinnings of enzalutamide resistance.

01-11-2018

The Lancet. Haematology

Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies.

01-11-2018

Journal of the National Cancer Institute

Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis.

01-11-2018

European journal of clinical investigation

Cancer and dementia: Two sides of the same coin?

01-11-2018

Epigenetics & chromatin

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a.

01-11-2018

Breast cancer research and treatment

Cost-effectiveness of monitoring endoxifen levels in breast cancer patients adjuvantly treated with tamoxifen.

01-11-2018

Clinical pharmacokinetics

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

01-11-2018

JAAD case reports

Remission of psoriasis during treatment with sorafenib.

01-11-2018

Acta crystallographica. Section F, Structural biology communications

Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.

01-11-2018

Annals of epidemiology

Indirect adjustment of relative risks of an exposure with multiple categories for an unmeasured confounder.

01-11-2018

Journal of hepatology

Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer.

01-11-2018

Pharmacological research

P-glycoprotein and breast cancer resistance protein restrict brigatinib brain accumulation and toxicity, and, alongside CYP3A, limit its oral availability.

01-11-2018

Abdominal radiology (New York)

Use of magnetic resonance imaging in rectal cancer patients: Society of Abdominal Radiology (SAR) rectal cancer disease-focused panel (DFP) recommendations 2017.

01-11-2018

European journal of cancer (Oxford, England : 1990)

Cancer Core Europe: A European cancer research alliance realizing a research infrastructure with critical mass and programmatic approach to cure cancer in the 21st century.

01-11-2018

Molecular oncology

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome.

01-11-2018

European journal of cancer (Oxford, England : 1990)

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

01-11-2018

European journal of cancer (Oxford, England : 1990)

Monitoring potentially modifiable lifestyle factors in cancer survivors: A narrative review on currently available methodologies and innovations for large-scale surveillance.

01-11-2018

The Lancet. Oncology

DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.

01-11-2018

International journal of radiation oncology, biology, physics

Radiation-Induced Lung Density Changes on CT Scan for NSCLC: No Impact of Dose-Escalation Level or Volume.

01-11-2018

Clinical and translational radiation oncology

Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial.

01-11-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Impact of a web-based prostate cancer treatment decision aid on patient-reported decision process parameters: results from the Prostate Cancer Patient Centered Care trial.

01-11-2018

Endocrine-related cancer

Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond.

31-10-2018

Disease models & mechanisms

Immune regulation of metastasis: mechanistic insights and therapeutic opportunities.

24-10-2018

BMC cancer

Preoperative image-guided identification of response to neoadjuvant chemoradiotherapy in esophageal cancer (PRIDE): a multicenter observational study.

20-10-2018

Journal of the American Chemical Society

Photoactivation of MDM2 Inhibitors: Controlling Protein-Protein Interaction with Light.

17-10-2018

International journal of cancer

P-glycoprotein (MDR1/ABCB1) restricts brain accumulation and cytochrome P450-3A (CYP3A) limits oral availability of the novel ALK/ROS1 inhibitor lorlatinib.

15-10-2018

Methods in molecular biology (Clifton, N.J.)

Development of Patient-Derived Tumor Xenograft Models.

14-10-2018

Journal of immunotherapy (Hagerstown, Md. : 1997)

Treatment With Tumor-infiltrating Lymphocytes in Advanced Melanoma: Evaluation of Early Clinical Implementation of an Advanced Therapy Medicinal Product.

10-10-2018

BMC health services research

Development of a benchmark tool for cancer centers; results from a pilot exercise.

10-10-2018

Nucleosides, nucleotides & nucleic acids

Development and validation of a quantitative method for thymidine phosphorylase activity in peripheral blood mononuclear cells.

05-10-2018

BMC bioinformatics

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.

04-10-2018

ESMO open

Report on the status of women occupying leadership roles in oncology.

03-10-2018

ESMO open

Gender-related challenges facing oncologists: the results of the ESMO Women for Oncology Committee survey.

03-10-2018

Journal for immunotherapy of cancer

Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option.

03-10-2018