Publications

Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

01-03-2014

European urology

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.

01-03-2014

Clinical pharmacokinetics

Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study.

01-03-2014

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Association between metformin use and mortality in patients with prostate cancer: explained by confounding by indication?

01-03-2014

Molecular pharmacology

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

01-03-2014

Medical physics

Multi-institutional dosimetric and geometric commissioning of image-guided small animal irradiators.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The course of health-related quality of life in head and neck cancer patients treated with chemoradiation: a prospective cohort study.

01-03-2014

Annals of oncology : official journal of the European Society for Medical Oncology

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

01-03-2014

Current opinion in oncology

The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose-response relationship with clinical outcome for lung stereotactic body radiotherapy (SBRT) delivered via online image guidance.

01-03-2014

Human brain mapping

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.

01-03-2014

European journal of cancer (Oxford, England : 1990)

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983.

01-03-2014

Cancer letters

Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.

01-03-2014

Cell reports

Determining lineage pathways from cellular barcoding experiments.

27-02-2014

PloS one

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

22-02-2014

Cell cycle (Georgetown, Tex.)

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

21-02-2014

ACS chemical biology

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection.

21-02-2014

British journal of cancer

Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.

18-02-2014

British journal of cancer

Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity.

18-02-2014

British journal of cancer

The impact of organisational external peer review on colorectal cancer treatment and survival in the Netherlands.

18-02-2014

Nature communications

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

13-02-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

01-02-2014

Journal of medical genetics

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.

01-02-2014

EMBO molecular medicine

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

01-02-2014

Breast cancer research and treatment

Mammographic screening detects low-risk tumor biology breast cancers.

01-02-2014

Annals of surgical oncology

Reply to "Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on 'Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Ann Surg Oncol. 2013;20(7):2227-35'".

01-02-2014

Nature reviews. Urology

Urological complications after treatment of cervical cancer.

01-02-2014

European journal of radiology

Avoiding preoperative breast MRI when conventional imaging is sufficient to stage patients eligible for breast conserving therapy.

01-02-2014

Cell death and differentiation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

01-02-2014

Journal of pharmaceutical sciences

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

01-02-2014

Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

01-02-2014

Molecular cancer therapeutics

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

01-02-2014

Current opinion in genetics & development

Finding effective cancer therapies through loss of function genetic screens.

01-02-2014

EMBO reports

RBR E3-ligases at work.

01-02-2014

Breast cancer research and treatment

Long-term impact of the 70-gene signature on breast cancer outcome.

01-02-2014

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

01-02-2014

Breast cancer research and treatment

Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care.

01-02-2014

Breast (Edinburgh, Scotland)

Time trends and inter-hospital variation in treatment and axillary staging of patients with ductal carcinoma in situ of the breast in the era of screening in Southern Netherlands.

01-02-2014

World journal of urology

Do targeted agents offer clinical benefit as presurgical therapy?

01-02-2014

Nederlands tijdschrift voor geneeskunde

[Biobanks and the return of results to donors].

30-01-2014

Oncogene

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.

30-01-2014

BMC cancer

The Nightingale study: rationale, study design and baseline characteristics of a prospective cohort study on shift work and breast cancer risk among nurses.

29-01-2014

Scientific reports

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

24-01-2014

Journal of immunology (Baltimore, Md. : 1950)

HLA micropolymorphisms strongly affect peptide-MHC multimer-based monitoring of antigen-specific CD8+ T cell responses.

15-01-2014

PloS one

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

15-01-2014

BMC cancer

The efficacy of a standardized questionnaire in facilitating personalized communication about problems encountered in cancer genetic counseling: design of a randomized controlled trial.

15-01-2014

Frontiers in genetics

Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.

07-01-2014

The Journal of investigative dermatology

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

01-01-2014

Immunological reviews

TCR repertoires of intratumoral T-cell subsets.

01-01-2014

European journal of nuclear medicine and molecular imaging

Sequential (18)F-FDG PET/CT for early prediction of complete pathological response in breast and axilla during neoadjuvant chemotherapy.

01-01-2014