Publications

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.

01-09-1998

Anti-cancer drugs

Phase I and pharmacologic study of weekly doxorubicin and 1 h infusional paclitaxel in patients with advanced breast cancer.

01-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.

07-08-1998

Journal of the National Cancer Institute

Availability of PSC833, a substrate and inhibitor of P-glycoproteins, in various concentrations of serum.

05-08-1998

Anti-cancer drugs

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

01-08-1998

Hepatology (Baltimore, Md.)

Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.

01-08-1998

Journal of cell science

Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.

01-08-1998

Biochemical and biophysical research communications

Genomic organization of the human alpha 3 integrin subunit gene.

30-07-1998

The Journal of cell biology

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

13-07-1998

Experimental lung research

Genetics of quantitative and qualitative aspects of lung tumorigenesis in the mouse: multiple interacting Susceptibility to lung cancer (Sluc) genes with large effects.

11-07-1998

Oncogene

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse.

09-07-1998

Molecular and biochemical parasitology

The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.

01-07-1998

European journal of immunology

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2.

01-07-1998

European journal of cancer (Oxford, England : 1990)

Quality of life assessment in daily clinical oncology practice: a feasibility study.

01-07-1998

Journal of clinical epidemiology

Comparison of patient and proxy EORTC QLQ-C30 ratings in assessing the quality of life of cancer patients.

01-07-1998

Blood

The bactericidal/permeability-increasing protein (BPI) is present in specific granules of human eosinophils.

15-06-1998

Journal of chromatography. B, Biomedical sciences and applications

Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.

12-06-1998

Electrophoresis

High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.

01-06-1998

Journal of cell science

Ligand-independent role of the beta 4 integrin subunit in the formation of hemidesmosomes.

01-06-1998

Anti-cancer drugs

Continuous infusion of low-dose topotecan: pharmacokinetics and pharmacodynamics during a phase II study in patients with small cell lung cancer.

01-06-1998

Pharmacological research

The pharmacological role of P-glycoprotein in the intestinal epithelium.

01-06-1998

Cancer research

Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.

01-06-1998

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis.

01-06-1998

Molecular and cellular biology

Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.

01-06-1998

Genes & development

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

01-06-1998

Molecular and biochemical parasitology

Changes in expression site control and DNA modification in Trypanosoma brucei during differentiation of the bloodstream form to the procyclic form.

15-05-1998

Journal of chromatography. B, Biomedical sciences and applications

Influence of Cremophor EL on the quantification of paclitaxel in plasma using high-performance liquid chromatography with solid-phase extraction as sample pretreatment.

08-05-1998

Analytical biochemistry

The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.

01-05-1998

Genes & development

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

15-04-1998

Cancer chemotherapy and pharmacology

A clinical pharmacokinetics study of carzelesin given by short-term intravenous infusion in a phase I study.

02-04-1998

The EMBO journal

The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.

01-04-1998

The Journal of clinical investigation

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

01-04-1998

Annals of oncology : official journal of the European Society for Medical Oncology

Malignant effusions contain lysophosphatidic acid (LPA)-like activity.

01-04-1998

The Journal of biological chemistry

CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.

27-03-1998

Current biology : CB

Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways.

26-03-1998

The Journal of cell biology

Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src.

09-03-1998

Proceedings of the National Academy of Sciences of the United States of America

beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.

03-03-1998

Molecular and biochemical parasitology

Control of VSG gene expression sites in Trypanosoma brucei.

01-03-1998

Cell adhesion and communication

Glomerular extracellular matrix components and integrins.

01-03-1998

Cancer treatment reviews

Cisplatin resistance and DNA repair.

18-02-1998

Journal of the National Cancer Institute

Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high-dose versus standard-dose chemotherapy.

04-02-1998

Nederlands tijdschrift voor geneeskunde

[Last word on hormone replacement and breast cancer?].

17-01-1998

Methods in molecular medicine

Saturating mutagenesis and characterization of a herpesvirus genome using in vivo reconstitution of virus from cloned subgenomic regions.

01-01-1998

Cellular and molecular life sciences : CMLS

Functional analysis of mouse Polycomb group genes.

01-01-1998

International journal of clinical pharmacology and therapeutics

Pharmacological insights from P-glycoprotein knockout mice.

01-01-1998

European journal of cancer (Oxford, England : 1990)

Intraperitoneal cisplatin with regional hyperthermia in advanced ovarian cancer: pharmacokinetics and cisplatin-DNA adduct formation in patients and ovarian cancer cell lines.

01-01-1998

Pharmacological research

Clinical research on antiangiogenic therapy.

01-01-1998

Biochimica et biophysica acta

E2F: a nodal point in cell cycle regulation.

09-12-1997

Developmental dynamics : an official publication of the American Association of Anatomists

Spatial and temporal expression of the beta1D integrin during mouse development.

01-12-1997

Molecular and biochemical parasitology

beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida.

01-12-1997