Publications

Nature genetics

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.

01-06-2020

European journal of epidemiology

Pathology-confirmed versus non pathology-confirmed cancer diagnoses: incidence, participant characteristics, and survival.

01-06-2020

Clinical pharmacokinetics

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-06-2020

Drugs in R&D

Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology.

01-06-2020

BMJ open

Health-related quality Of Life In patients with advanced Soft TIssue sarcomas treated with Chemotherapy (The HOLISTIC study): protocol for an international observational cohort study.

01-06-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Professional quality of life and burnout amongst radiation oncologists: The impact of alexithymia and empathy.

01-06-2020

The Journal of experimental medicine

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.

01-06-2020

Immuno-oncology technology

IOTECH in times of COVID-19.

01-06-2020

Science (New York, N.Y.)

The human tumor microbiome is composed of tumor type-specific intracellular bacteria.

29-05-2020

Communications biology

A mouse model that is immunologically tolerant to reporter and modifier proteins.

29-05-2020

PloS one

Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development.

27-05-2020

Cancers

RNA-Sequencing of Tumor-Educated Platelets, a Novel Biomarker for Blood-Based Sarcoma Diagnostics.

27-05-2020

PloS one

Computed tomography-derived radiomic signature of head and neck squamous cell carcinoma (peri)tumoral tissue for the prediction of locoregional recurrence and distant metastasis after concurrent chemo-radiotherapy.

23-05-2020

Journal of cell science

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae.

22-05-2020

NPJ breast cancer

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

22-05-2020

PloS one

A detailed insight in the high risks of hospitalizations in long-term childhood cancer survivors-A Dutch LATER linkage study.

20-05-2020

Science translational medicine

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.

20-05-2020

Immunity

The CD47-SIRPα Immune Checkpoint.

19-05-2020

NPJ breast cancer

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

16-05-2020

NPJ breast cancer

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

16-05-2020

Scientific reports

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

15-05-2020

Cancer research

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.

15-05-2020

International journal of pharmaceutics

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice.

15-05-2020

PloS one

Early budget impact analysis on magnetic seed localization for non-palpable breast cancer surgery.

14-05-2020

Journal of medical Internet research

Web-Based Self-Management for Patients With Lymphoma: Assessment of the Reach of Intervention of a Randomized Controlled Trial.

14-05-2020

NPJ breast cancer

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

12-05-2020

NPJ breast cancer

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

12-05-2020

NPJ breast cancer

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

12-05-2020

Biosensors

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

11-05-2020

Pharmaceutical research

Phase I pharmacological study of continuous chronomodulated capecitabine treatment.

07-05-2020

Molecular cell

Life in the (Pluripotent) Fast Lane: Cdk1 Preserves the Epigenome to Maintain Pluripotency.

07-05-2020

Cancers

Surgery for Unresectable Stage IIIC and IV Melanoma in the Era of New Systemic Therapy.

07-05-2020

Molecular cell

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

07-05-2020

Journal of cancer research and therapeutics

Human papillomavirus-negative epithelial proliferations resembling condylomata acuminata in a patient receiving vemurafenib for Stage IV melanoma.

05-05-2020

Cell reports

Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine.

05-05-2020

CPT: pharmacometrics & systems pharmacology

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation.

01-05-2020

European journal of cancer (Oxford, England : 1990)

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure: real life data from a therapeutic drug monitoring programme.

01-05-2020

European radiology

Added value of MRI to endoscopic and endosonographic response assessment after neoadjuvant chemoradiotherapy in oesophageal cancer.

01-05-2020

Oncogene

Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D dosimetric verification of unity MR-linac treatments by portal dosimetry.

01-05-2020

The Lancet. Oncology

Outcome measures in multimodal rectal cancer trials.

01-05-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

Association of Anti-TNF with Decreased Survival in Steroid Refractory Ipilimumab and Anti-PD1-Treated Patients in the Dutch Melanoma Treatment Registry.

01-05-2020

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.

01-05-2020

Magnetic resonance imaging

A workflow for automated segmentation of the liver surface, hepatic vasculature and biliary tree anatomy from multiphase MR images.

01-05-2020

Pigment cell & melanoma research

Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single-centre experience in patients with BRAF-mutated melanoma.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognosis of acute coronary syndromes after radiotherapy for breast cancer.

01-05-2020

Head & neck

Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.

01-05-2020

Journal of medical genetics

Three-step site-directed mutagenesis screen identifies pathogenic MLH1 variants associated with Lynch syndrome.

01-05-2020

Nature cancer

Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects.

01-05-2020

Cancer chemotherapy and pharmacology

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

01-05-2020