Publications

Clinical and translational radiation oncology

Enhancing radiation response by a second-generation TRAIL receptor agonist using a new in vitro organoid model system.

01-09-2020

European journal of cancer (Oxford, England : 1990)

Survival outcomes of patients with advanced mucosal melanoma diagnosed from 2013 to 2017 in the Netherlands - A nationwide population-based study.

01-09-2020

Critical reviews in oncology/hematology

Observed versus modelled lifetime overall survival of targeted therapies and immunotherapies for advanced non-small cell lung cancer patients - A systematic review.

01-09-2020

Cold Spring Harbor perspectives in biology

Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy.

01-09-2020

The European journal of health economics : HEPAC : health economics in prevention and care

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN).

01-09-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Gross tumour volume delineation in anal cancer on T2-weighted and diffusion-weighted MRI - Reproducibility between radiologists and radiation oncologists and impact of reader experience level and DWI image quality.

01-09-2020

European journal of cancer (Oxford, England : 1990)

Impact of the coronavirus disease 2019 pandemic on cancer treatment: the patients' perspective.

01-09-2020

The Laryngoscope

Optimizing Survival Predictions of Hypopharynx Cancer: Development of a Clinical Prediction Model.

01-09-2020

Nat Commun.

Sex differences in oncogenic mutational processes

28-08-2020

Proceedings of the National Academy of Sciences of the United States of America

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8⁺ T cells.

25-08-2020

Cell reports

Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.

25-08-2020

BMC cancer

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.

20-08-2020

BMC cancer

Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study.

18-08-2020

International journal of cancer

A prospective observational registry evaluating clinical outcomes of Radium-223 treatment in a nonstudy population.

15-08-2020

Toxicology and applied pharmacology

Human organic anion transporting polypeptide (OATP) 1B3 and mouse OATP1A/1B affect liver accumulation of Ochratoxin A in mice.

15-08-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones.

15-08-2020

International journal of cancer

EORTC SPECTA-AYA: A unique molecular profiling platform for adolescents and young adults with cancer in Europe.

15-08-2020

Biology open

Comparative interactomics analysis reveals potential regulators of α6β4 distribution in keratinocytes.

13-08-2020

Cancers

Neoadjuvant Systemic Treatment of Primary Angiosarcoma.

12-08-2020

Breast cancer research : BCR

Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets.

11-08-2020

Sarcoma

Assessing the Desmoid-Type Fibromatosis Patients' Voice: Comparison of Health-Related Quality of Life Experiences from Patients of Two Countries.

11-08-2020

Nature communications

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-08-2020

EJNMMI research

A DROP-IN beta probe for robot-assisted ⁶⁸Ga-PSMA radioguided surgery: first ex vivo technology evaluation using prostate cancer specimens.

06-08-2020

Brachytherapy

Applicator visualization using ultrashort echo time MRI for high-dose-rate endorectal brachytherapy.

05-08-2020

Journal for immunotherapy of cancer

Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.

01-08-2020

The Lancet. Oncology

100 European core quality standards for cancer care and research centres.

01-08-2020

Acta oncologica (Stockholm, Sweden)

Health-related quality of life and symptom burden of epithelioid hemangioendothelioma patients: a global patient-driven Facebook study in a very rare malignancy.

01-08-2020

European urology oncology

Distribution of Molecular Subtypes in Muscle-invasive Bladder Cancer Is Driven by Sex-specific Differences.

01-08-2020

Nature genetics

The DNA methylation landscape of advanced prostate cancer.

01-08-2020

Annals of surgical oncology

Selection of Patients for Organ Preservation After Chemoradiotherapy: MRI Identifies Poor Responders Who Can Go Straight to Surgery.

01-08-2020

Genes & development

Cells of origin of lung cancers: lessons from mouse studies.

01-08-2020

Investigational new drugs

Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).

01-08-2020

Therapeutic drug monitoring

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs.

01-08-2020

Head & neck

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update.

01-08-2020

International journal of epidemiology

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

01-08-2020

Breast (Edinburgh, Scotland)

The impact of menstruation persistence or recovery after chemotherapy on survival in young patients with hormone receptor negative breast cancer.

01-08-2020

Nature reviews. Immunology

Immune crosstalk in cancer progression and metastatic spread: a complex conversation.

01-08-2020

European journal of human genetics : EJHG

The uptake of predictive DNA testing in 40 families with a pathogenic BRCA1/BRCA2 variant. An evaluation of the proband-mediated procedure.

01-08-2020

Investigational new drugs

Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).

01-08-2020

Journal of medical genetics

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation.

01-08-2020

Nature genetics

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

01-08-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Feasibility of cone beam CT-guided library of plans strategy in pre-operative gastric cancer radiotherapy.

01-08-2020

European journal of clinical pharmacology

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

01-08-2020

Clinical psychology review

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.

01-08-2020

Investigational new drugs

Mass balance and metabolite profiling of ¹⁴C-guadecitabine in patients with advanced cancer.

01-08-2020

Pharmacology research & perspectives

No relation between docetaxel administration route and high-grade diarrhea incidence.

01-08-2020

European journal of cancer (Oxford, England : 1990)

Adjuvant chemotherapy in small node-negative triple-negative breast cancer.

01-08-2020

Radiology

Radiogenomic Analysis of Breast Cancer by Linking MRI Phenotypes with Tumor Gene Expression.

01-08-2020

Acta oncologica (Stockholm, Sweden)

First system for fully-automated multi-criterial treatment planning for a high-magnetic field MR-Linac applied to rectal cancer.

01-08-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Updated efficacy results from the JAVELIN Renal 101 trial: first-line avelumab plus axitinib versus sunitinib in patients with advanced renal cell carcinoma.

01-08-2020