Publications

Investigational new drugs

Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).

01-08-2020

Journal of medical genetics

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation.

01-08-2020

Nature genetics

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

01-08-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Feasibility of cone beam CT-guided library of plans strategy in pre-operative gastric cancer radiotherapy.

01-08-2020

European journal of clinical pharmacology

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

01-08-2020

Clinical psychology review

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.

01-08-2020

Investigational new drugs

Mass balance and metabolite profiling of ¹⁴C-guadecitabine in patients with advanced cancer.

01-08-2020

Pharmacology research & perspectives

No relation between docetaxel administration route and high-grade diarrhea incidence.

01-08-2020

European journal of cancer (Oxford, England : 1990)

Adjuvant chemotherapy in small node-negative triple-negative breast cancer.

01-08-2020

Radiology

Radiogenomic Analysis of Breast Cancer by Linking MRI Phenotypes with Tumor Gene Expression.

01-08-2020

Acta oncologica (Stockholm, Sweden)

First system for fully-automated multi-criterial treatment planning for a high-magnetic field MR-Linac applied to rectal cancer.

01-08-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Updated efficacy results from the JAVELIN Renal 101 trial: first-line avelumab plus axitinib versus sunitinib in patients with advanced renal cell carcinoma.

01-08-2020

Thyroid : official journal of the American Thyroid Association

Long-Term Effects of Radioiodine Treatment on Female Fertility in Survivors of Childhood Differentiated Thyroid Carcinoma.

01-08-2020

International journal of cancer

Ascertainment of cancer in longitudinal research: The concordance between the Rotterdam Study and the Netherlands Cancer Registry.

01-08-2020

Cancer

Patterns and predictors of cancer-related fatigue in ovarian and endometrial cancers: 1-year longitudinal study.

01-08-2020

Journal for immunotherapy of cancer

Rationalizing the pathway to personalized neoadjuvant immunotherapy: the Lombard Street Approach.

01-08-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Management of early melanoma recurrence despite adjuvant anti-PD-1 antibody therapy^☆.

01-08-2020

British journal of clinical pharmacology

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

01-08-2020

Nucleosides, nucleotides & nucleic acids

Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase.

31-07-2020

BMC cancer

Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness.

31-07-2020

Cancers

The Perceived Impact of Length of the Diagnostic Pathway Is Associated with Health-Related Quality of Life of Sarcoma Survivors: Results from the Dutch Nationwide SURVSARC Study.

28-07-2020

Cancers

Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

27-07-2020

Breast cancer research : BCR

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.

25-07-2020

Cell reports

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

21-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Stem cell lineage survival as a noisy competition for niche access.

21-07-2020

Trials

Internet-based cognitive rehabilitation for WORking Cancer survivors (i-WORC): study protocol of a randomized controlled trial.

20-07-2020

Insights into imaging

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice.

16-07-2020

Molecular cell

RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.

16-07-2020

Science translational medicine

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

15-07-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.

15-07-2020

ACS infectious diseases

A Supramolecular Platform Technology for Bacterial Cell Surface Modification.

10-07-2020

PloS one

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

09-07-2020

BMC cancer

Design of the PROstate cancer follow-up care in Secondary and Primary hEalth Care study (PROSPEC): a randomized controlled trial to evaluate the effectiveness of primary care-based follow-up of localized prostate cancer survivors.

08-07-2020

Nature communications

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

03-07-2020

Journal of translational medicine

Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma.

03-07-2020

Scientific reports

Epigenetic profiling demarcates molecular subtypes of muscle-invasive bladder cancer.

02-07-2020

JAMA network open

Association of Image-Guided Navigation With Complete Resection Rate in Patients With Locally Advanced Primary and Recurrent Rectal Cancer: A Nonrandomized Controlled Trial.

01-07-2020

JAMA oncology

De-Escalating Breast Cancer Surgery for Low-Risk Ductal Carcinoma in Situ.

01-07-2020

Clinical pharmacokinetics

Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.

01-07-2020

Journal of cancer research and clinical oncology

Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.

01-07-2020

International journal of radiation oncology, biology, physics

Correlating Dose Variables with Local Tumor Control in Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer: A Modeling Study on 1500 Individual Treatments.

01-07-2020

Clinical pharmacology in drug development

Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.

01-07-2020

Life science alliance

Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.

01-07-2020

Learning health systems

Learning health care systems: Highly needed but challenging.

01-07-2020

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic.

01-07-2020

Familial cancer

Patient-reported burden of intensified surveillance and surgery in high-risk individuals under pancreatic cancer surveillance.

01-07-2020

Journal of the National Cancer Institute. Monographs

Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Rationale and Framework for the Monograph and Overview of Eligible Studies.

01-07-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma.

01-07-2020

SLAS discovery : advancing life sciences R & D

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

01-07-2020

Lasers in surgery and medicine

Toward assessment of resection margins using hyperspectral diffuse reflection imaging (400-1,700 nm) during tongue cancer surgery.

01-07-2020