Publications

Cancer research

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL.

01-05-1996

The Journal of biological chemistry

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors.

12-04-1996

British journal of cancer

Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support.

01-04-1996

Current opinion in immunology

Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes.

01-04-1996

Trends in genetics : TIG

Cycling in Switzerland.

01-04-1996

Annals of oncology : official journal of the European Society for Medical Oncology

Feasibility, psychometric performance, and stability across modes of administration of the CARES-SF.

01-04-1996

Molecular biology of the cell

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

01-04-1996

The Journal of biological chemistry

Cleavage of the alpha6A subunit is essential for activation of the alpha6Abeta1 integrin by phorbol 12-myristate 13-acetate.

29-03-1996

The EMBO journal

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

15-03-1996

The Journal of biological chemistry

Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.

08-03-1996

The Journal of clinical investigation

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

01-03-1996

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Telephone-based nursing intervention improves the effectiveness of the informed consent process in cancer clinical trials.

01-03-1996

Bailliere's clinical haematology

Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.

01-03-1996

British journal of cancer

Immunoscintigraphy of small-cell lung cancer xenografts with anti neural cell adhesion molecule monoclonal antibody, 123C3: improvement of tumour uptake by internalisation.

01-02-1996

Science (New York, N.Y.)

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

19-01-1996

The EMBO journal

Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor.

02-01-1996

Cancer chemotherapy and pharmacology

Pharmacokinetics and pharmacodynamics of topotecan given on a daily-times-five schedule in phase II clinical trials using a limited-sampling procedure.

01-01-1996

Investigational new drugs

Purity determinations in the bulk drug of the novel indoloquinone antitumor agent EO9.

01-01-1996

Anti-cancer drugs

Tissue distribution, metabolism and excretion of paclitaxel in mice.

01-01-1996

Cancer chemotherapy and pharmacology

Evaluation of formulas using the serum creatinine level to calculate the optimal dosage of carboplatin.

01-01-1996

Cancer chemotherapy and pharmacology

Unchanged pharmacokinetics of etoposide given by intra-arterial hepatic infusion as compared with i.v. infusion.

01-01-1996

Current topics in microbiology and immunology

Role of Tiam 1 in Rac-mediated signal transduction pathways.

01-01-1996

Archives of medical research

Antigenic variation in trypanosomes.

01-01-1996

Journal of chromatography. B, Biomedical applications

Quantification of paclitaxel metabolites in human plasma by high-performance liquid chromatography.

15-12-1995

Oncogene

Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells.

07-12-1995

Clinical otolaryngology and allied sciences

Heat and moisture exchangers as a treatment option in the post-operative rehabilitation of laryngectomized patients.

01-12-1995

Gastroenterology

Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.

01-12-1995

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic analysis of the new antitumour drug N-benzoylstaurosporine (CGP 41 251) and four potential metabolites in micro-volumes of plasma.

01-12-1995

PDA journal of pharmaceutical science and technology

The influence of formulation excipients on the stability of the novel antitumor agent carzelesin (U-80,244).

01-11-1995

Biochemical Society transactions

Involvement of the cell surface-bound mucin, episialin/MUC1, in progression of human carcinomas.

01-11-1995

Journal of the National Cancer Institute

Roles of radiotherapy and smoking in lung cancer following Hodgkin's disease.

18-10-1995

The Journal of clinical investigation

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

01-10-1995

Therapeutic drug monitoring

Monitoring carboplatin concentrations in saliva: a replacement for plasma ultrafiltrate measurements?

01-10-1995

European journal of cancer (Oxford, England : 1990)

Cancer incidence in The Netherlands in 1989 and 1990: first results of the nationwide Netherlands cancer registry. Coordinating Committee for Regional Cancer Registries.

01-10-1995

European journal of cancer (Oxford, England : 1990)

Risk factors for the development of oesophageal cancer as a second primary tumour.

01-10-1995

Proceedings of the National Academy of Sciences of the United States of America

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

15-08-1995

FEBS letters

A novel beta 1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle.

07-08-1995

Current biology : CB

Transcriptional regulation. Flipping the Myc switch.

01-08-1995

Cell

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer.

28-07-1995

Cancer research

A gene for susceptibility to small intestinal cancer, ssic1, maps to the distal part of mouse chromosome 4.

15-07-1995

Cell

Antigenic variation in malaria.

14-07-1995

The EMBO journal

BS69, a novel adenovirus E1A-associated protein that inhibits E1A transactivation.

03-07-1995

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I clinical and pharmacokinetic study of topotecan administered by a 24-hour continuous infusion.

01-07-1995

European journal of cancer (Oxford, England : 1990)

Multidrug resistance and the role of P-glycoprotein knockout mice.

01-07-1995

British journal of cancer

CRC/EORTC/NCI Joint Formulation Working Party: experiences in the formulation of investigational cytotoxic drugs.

01-07-1995

Journal of chromatography. B, Biomedical applications

High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma.

09-06-1995

Genes & development

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

01-06-1995

The EMBO journal

Proviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.

01-06-1995

Molecular and cellular biology

E2F-5, a new E2F family member that interacts with p130 in vivo.

01-06-1995

Cell adhesion and communication

An alternatively spliced exon in the extracellular domain of the human alpha 6 integrin subunit--functional analysis of the alpha 6 integrin variants.

01-05-1995