Publications

Molecular pharmacology

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

01-05-2005

Oncogene

Getting in and out of mitosis with Polo-like kinase-1.

18-04-2005

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

09-04-2005

Cancer research

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

01-04-2005

Medical physics

Respiratory correlated cone beam CT.

01-04-2005

Genes & development

Mouse models for human lung cancer.

15-03-2005

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

01-03-2005

Anti-cancer drugs

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

01-03-2005

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility.

01-03-2005

Cancer chemotherapy and pharmacology

Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours.

01-03-2005

British journal of clinical pharmacology

Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL.

01-03-2005

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I clinical and pharmacokinetic study of kahalalide F in patients with advanced androgen refractory prostate cancer.

01-03-2005

The British journal of dermatology

Predictions of skin cancer incidence in the Netherlands up to 2015.

01-03-2005

Molecular and cellular biology

Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1.

01-03-2005

Hereditary cancer in clinical practice

Withdrawal from genetic counselling for cancer.

15-02-2005

Genes & development

Frat is dispensable for canonical Wnt signaling in mammals.

15-02-2005

Molecular cell

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

04-02-2005

Genes & development

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

01-02-2005

Nature medicine

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

01-02-2005

Gastroenterology

Screening behavior of individuals at high risk for colorectal cancer.

01-02-2005

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

01-02-2005

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.

01-02-2005

European journal of cancer (Oxford, England : 1990)

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.

01-02-2005

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Blood

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

01-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

01-01-2005

The Journal of biological chemistry

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

31-12-2004

Current biology : CB

Significant role for p16INK4a in p53-independent telomere-directed senescence.

29-12-2004

Nederlands tijdschrift voor geneeskunde

[New insights in the adjuvant treatment of gastric cancer].

18-12-2004

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Methods in molecular biology (Clifton, N.J.)

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

04-12-2004

European journal of cancer (Oxford, England : 1990)

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

01-12-2004

Journal of mass spectrometry : JMS

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

01-12-2004

Cancer cell

Oncogene addiction: sometimes a temporary slavery.

01-12-2004

Acta crystallographica. Section D, Biological crystallography

Towards complete validated models in the next generation of ARP/wARP.

01-12-2004

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

01-12-2004

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Cancer cell death by programmed necrosis?

01-12-2004

Rapid communications in mass spectrometry : RCM

Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

02-11-2004

Cell cycle (Georgetown, Tex.)

Checkpoint adaptation and recovery: back with Polo after the break.

01-11-2004

Medical physics

The long-term stability of amorphous silicon flat panel imaging devices for dosimetry purposes.

01-11-2004

British journal of cancer

A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer.

18-10-2004

The Journal of biological chemistry

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

15-10-2004

The Journal of experimental medicine

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

04-10-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.

01-10-2004

Journal of cell science

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

01-10-2004

Genes & development

Epigenetics and cancer.

01-10-2004

Molecular cell

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells.

10-09-2004