Publications

Journal of pharmacokinetics and pharmacodynamics

A semi-physiological population pharmacokinetic model describing the non-linear disposition of indisulam.

01-10-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel.

01-10-2006

Die Pharmazie

Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

01-10-2006

Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006

Nederlands tijdschrift voor geneeskunde

[Defining trials of medicinal products according to the revised Dutch Medical Research in Human Subjects Act (WMO)].

23-09-2006

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

British journal of cancer

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer.

18-09-2006

Nature genetics

Characterization of the Drosophila melanogaster genome at the nuclear lamina.

01-09-2006

Nature methods

shRNA libraries and their use in cancer genetics.

01-09-2006

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

01-09-2006

Journal of mass spectrometry : JMS

Sensitive inductively coupled plasma mass spectrometry assay for the determination of platinum originating from cisplatin, carboplatin, and oxaliplatin in human plasma ultrafiltrate.

01-09-2006

Methods in enzymology

DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase.

30-08-2006

International journal of cancer

Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).

15-08-2006

Proceedings of the National Academy of Sciences of the United States of America

Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster.

08-08-2006

The Journal of biological chemistry

A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.

04-08-2006

Basic & clinical pharmacology & toxicology

Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.

01-08-2006

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Phase I and pharmacokinetic study of combined treatment with perifosine and radiation in patients with advanced solid tumours.

01-08-2006

Nature cell biology

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

01-08-2006

Genes & development

TXR1-mediated thrombospondin repression: a novel mechanism of resistance to taxanes?

01-08-2006

European journal of clinical pharmacology

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

01-08-2006

International journal of radiation oncology, biology, physics

Mid-ventilation CT scan construction from four-dimensional respiration-correlated CT scans for radiotherapy planning of lung cancer patients.

01-08-2006

European journal of nuclear medicine and molecular imaging

Mapping of treatment-induced apoptosis in normal structures: 99mTc-Hynic-rh-annexin V SPECT and CT image fusion.

01-08-2006

European journal of cancer (Oxford, England : 1990)

Translation and validation of the EORTC QLQ-C30 for use among Turkish and Moroccan ethnic minority cancer patients in the Netherlands.

01-08-2006

Expert review of neurotherapeutics

Blood-brain barrier and chemotherapeutic treatment of brain tumors.

01-08-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The impact of hormone replacement therapy on menopausal symptoms in younger high-risk women after prophylactic salpingo-oophorectomy.

01-08-2006

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

01-08-2006

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

01-08-2006

Cancer treatment reviews

Future opportunities in preventing cisplatin induced ototoxicity.

01-08-2006

Cold Spring Harbor symposia on quantitative biology

Genotype-phenotype relationships in a mouse model for human small-cell lung cancer.

28-07-2006

Journal of immunology (Baltimore, Md. : 1950)

Generation of T cell help through a MHC class I-restricted TCR.

15-07-2006

Blood

Gimap4 accelerates T-cell death.

15-07-2006

BMC cancer

Clinical management of women with metastatic breast cancer: a descriptive study according to age group.

06-07-2006

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

01-07-2006

Cell cycle (Georgetown, Tex.)

Immense promises for tiny molecules: uncovering miRNA functions.

01-07-2006

British journal of clinical pharmacology

Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional therapy to cancer patients.

01-07-2006

Molecular and cellular biology

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

01-07-2006

Medical physics

Comparison of ghosting effects for three commercial a-Si EPIDs.

01-07-2006

The Journal of pharmacology and experimental therapeutics

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

01-07-2006

The British journal of dermatology

An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis.

01-07-2006

Cell

Cross-species oncogenomics in cancer gene identification.

30-06-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Dose-finding phase I clinical and pharmacokinetic study of orally administered irinotecan in patients with advanced solid tumors.

15-06-2006

Molecular diagnosis & therapy

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

15-06-2006

The EMBO journal

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

07-06-2006

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Outcome of surgical treatment of pancreatic, peri-ampullary and ampullary cancer diagnosed in the south of The Netherlands: a cancer registry based study.

01-06-2006

Cancer chemotherapy and pharmacology

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice.

01-06-2006

Nature genetics

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

01-06-2006

Drug metabolism and disposition: the biological fate of chemicals

Saturable binding of indisulam to plasma proteins and distribution to human erythrocytes.

01-06-2006

The oncologist

Symptoms and treatment in cancer therapy-induced early menopause.

01-06-2006

Human immunology

Control of peripheral T cell survival: a delicate division of labor between cytokines and costimulatory molecules.

01-06-2006

International immunology

Constitutive expression of the pre-TCR enables development of mature T cells.

01-06-2006