Publications

Experimental cell research

Direct measurement of cyclic AMP diffusion and signaling through connexin43 gap junctional channels.

15-01-2007

The Biochemical journal

Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts.

15-01-2007

Journal of cell science

Synaptotagmin 3 deficiency in T cells impairs recycling of the chemokine receptor CXCR4 and thereby inhibits CXCL12 chemokine-induced migration.

15-01-2007

Physics in medicine and biology

Influence of the linac design on intensity-modulated radiotherapy of head-and-neck plans.

07-01-2007

The Journal of biological chemistry

Activation of TRPM7 channels by phospholipase C-coupled receptor agonists.

05-01-2007

Journal of pharmaceutical and biomedical analysis

Stability experiments in human urine with EO9 (apaziquone): a novel anticancer agent for the intravesical treatment of bladder cancer.

04-01-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Am J Pathol: The American journal of pathology

Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human

01-01-2007

Experimental cel research

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes

01-01-2007

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation.

01-01-2007

European journal of human genetics : EJHG

The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes.

01-01-2007

Molecular pharmacology

The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models.

01-01-2007

World journal of surgery

Which comorbid conditions predict complications after surgery for colorectal cancer?

01-01-2007

Cancer chemotherapy and pharmacology

A pharmacokinetic and safety study of a novel polymeric paclitaxel formulation for oral application.

01-01-2007

Nederlands tijdschrift voor geneeskunde

[The Nobel Prize in Physiology or Medicine for 2006 for the discovery of RNA interference].

30-12-2006

The Journal of biological chemistry

Telomerase-independent regulation of ATR by human telomerase RNA.

29-12-2006

Journal of cell science

KASH-domain proteins in nuclear migration, anchorage and other processes.

15-12-2006

The New England journal of medicine

Exploring the uses of RNAi--gene knockdown and the Nobel Prize.

07-12-2006

Journal of the National Cancer Institute

Change in cognitive function after chemotherapy: a prospective longitudinal study in breast cancer patients.

06-12-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Decreased risk of stroke among 10-year survivors of breast cancer.

01-12-2006

Trends in genetics : TIG

Knockout mouse models to study Wnt signal transduction.

01-12-2006

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

A validation study of the Dutch version of the Quality of Life-Cancer Survivor (QOL-CS) questionnaire in a group of prostate cancer survivors.

01-12-2006

European journal of cancer (Oxford, England : 1990)

Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.

01-12-2006

Cell

Re-evaluating cell-cycle regulation by E2Fs.

01-12-2006

Journal of mass spectrometry : JMS

Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

01-12-2006

Cell cycle (Georgetown, Tex.)

Senescence, wound healing and cancer: the PAI-1 connection.

01-12-2006

Genome research

Human heterochromatin proteins form large domains containing KRAB-ZNF genes.

01-12-2006

British journal of cancer

Molecular subtypes of breast cancer and amplification of topoisomerase II alpha: predictive role in dose intensive adjuvant chemotherapy.

20-11-2006

Cancer research

A causal role for the human tumor antigen preferentially expressed antigen of melanoma in cancer.

15-11-2006

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

New physiological functions for drug-transporting P-glycoproteins?

10-11-2006

Cancer

Long-term quality of life among Dutch prostate cancer survivors: results of a population-based study.

01-11-2006

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Relationship between clinical factors and the incidence of toxicity after intra-arterial chemoradiation for head and neck cancer.

01-11-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Flat dosing of carboplatin is justified in adult patients with normal renal function.

01-11-2006

European journal of cancer (Oxford, England : 1990)

Better quality of life among 10-15 year survivors of Hodgkin's lymphoma compared to 5-9 year survivors: a population-based study.

01-11-2006

European journal of cancer (Oxford, England : 1990)

Elderly patients with rectal cancer have a higher risk of treatment-related complications and a poorer prognosis than younger patients: a population-based study.

01-11-2006

Cancer cell

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

01-11-2006

European journal of cancer (Oxford, England : 1990)

Translation and validation of the SF-36 Health Survey for use among Turkish and Moroccan ethnic minority cancer patients in The Netherlands.

01-11-2006

Nature reviews. Cancer

Polycomb silencers control cell fate, development and cancer.

01-11-2006

Breast cancer research : BCR

Predicting a local recurrence after breast-conserving therapy by gene expression profiling.

31-10-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics.

15-10-2006

British journal of cancer

Phase II and pharmacological study of oral paclitaxel (Paxoral) plus ciclosporin in anthracycline-pretreated metastatic breast cancer.

09-10-2006

The Journal of cell biology

Kidney failure in mice lacking the tetraspanin CD151.

09-10-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical and pharmacologic study of the farnesyltransferase inhibitor tipifarnib in cancer patients with normal or mildly or moderately impaired hepatic function.

01-10-2006

Journal of pharmacokinetics and pharmacodynamics

A semi-physiological population pharmacokinetic model describing the non-linear disposition of indisulam.

01-10-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel.

01-10-2006

Die Pharmazie

Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

01-10-2006

Medical physics

Clinical experience with EPID dosimetry for prostate IMRT pre-treatment dose verification.

01-10-2006

Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006

Nederlands tijdschrift voor geneeskunde

[Defining trials of medicinal products according to the revised Dutch Medical Research in Human Subjects Act (WMO)].

23-09-2006

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006