Publications

Genomics data

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

01-03-2016

International journal of cancer

Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.

01-03-2016

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Using a discrete choice experiment to value the QLU-C10D: feasibility and sensitivity to presentation format.

01-03-2016

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Magnetic resonance imaging for prostate cancer radiotherapy.

01-03-2016

Journal of oncology practice

Identification of Key Gaps in Cancer Survivorship Research: Findings From the American Society of Clinical Oncology Survey.

01-03-2016

Medical physics

Clinical introduction of image lag correction for a cone beam CT system.

01-03-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Validation of automatic segmentation of ribs for NTCP modeling.

01-03-2016

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30.

01-03-2016

Lung cancer (Amsterdam, Netherlands)

Crizotinib-induced fatal fulminant liver failure.

01-03-2016

European urology

ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy.

01-03-2016

Haematologica

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08).

01-03-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Fractures of thoracic vertebrae in patients with locally advanced non-small cell lung carcinoma treated with intensity modulated radiotherapy.

01-03-2016

Journal of neurology

Strategies to target drugs to gliomas and CNS metastases of solid tumors.

01-03-2016

Medical & biological engineering & computing

Dynamic CT perfusion image data compression for efficient parallel processing.

01-03-2016

The AAPS journal

Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer.

01-03-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Differential analysis of local and regional failure in locally advanced non-small cell lung cancer patients treated with concurrent chemoradiotherapy.

01-03-2016

PloS one

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.

27-02-2016

The Journal of biological chemistry

Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.

26-02-2016

Nature

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.

25-02-2016

Oncogene

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.

25-02-2016

Molecular cell

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.

18-02-2016

Molecular cell

Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation.

18-02-2016

Molecular cell

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

18-02-2016

Breast cancer research : BCR

Genetic predisposition to ductal carcinoma in situ of the breast.

17-02-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors.

15-02-2016

Behavioural brain research

Neurobiological changes by cytotoxic agents in mice.

15-02-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.

15-02-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for the tyrosine kinase inhibitor afatinib in mouse plasma using salting-out liquid-liquid extraction.

15-02-2016

The EMBO journal

Touch, act and go: landing and operating on nucleosomes.

15-02-2016

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

10-02-2016

BMC Bioinformatics

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

09-02-2016

BMC cancer

Scenario drafting for early technology assessment of next generation sequencing in clinical oncology.

06-02-2016

BMC medical ethics

Exceptions to the rule of informed consent for research with an intervention.

06-02-2016

Circulation research

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.

05-02-2016

Molecular cell

HELB Is a Feedback Inhibitor of DNA End Resection.

04-02-2016

Proceedings of the National Academy of Sciences of the United States of America

Enterovirus D68 receptor requirements unveiled by haploid genetics.

02-02-2016

British journal of cancer

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers.

02-02-2016

European journal of cancer (Oxford, England : 1990)

Renal function, body surface area, and age are associated with risk of early-onset fluoropyrimidine-associated toxicity in patients treated with capecitabine-based anticancer regimens in daily clinical care.

01-02-2016

International journal of cancer

Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model.

01-02-2016

DNA repair

The conserved molecular machinery in DNA mismatch repair enzyme structures.

01-02-2016

European journal of cancer (Oxford, England : 1990)

Perioperative treatment and radical cystectomy for bladder cancer--a population based trend analysis of 10,338 patients in the Netherlands.

01-02-2016

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Cytoreduction and hyperthermic intraperitoneal chemotherapy: The learning curve reassessed.

01-02-2016

PLoS genetics

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

01-02-2016

Cancer discovery

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

01-02-2016

World journal of urology

Neoadjuvant induction dose-dense MVAC for muscle invasive bladder cancer: efficacy and safety compared with classic MVAC and gemcitabine/cisplatin.

01-02-2016

Inflammatory bowel diseases

CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.

01-02-2016

Oncoimmunology

Systemic inflammation: Cancer's long-distance reach to maximize metastasis.

01-02-2016

Nature biotechnology

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

01-02-2016

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Correlates of physical activity among colorectal cancer survivors: results from the longitudinal population-based profiles registry.

01-02-2016

Genetics in medicine : official journal of the American College of Medical Genetics

Does rapid genetic counseling and testing in newly diagnosed breast cancer patients cause additional psychosocial distress? results from a randomized clinical trial.

01-02-2016

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers.

Using a discrete choice experiment to value the QLU-C10D: feasibility and sensitivity to presentation format.

Magnetic resonance imaging for prostate cancer radiotherapy.

Identification of Key Gaps in Cancer Survivorship Research: Findings From the American Society of Clinical Oncology Survey.

Clinical introduction of image lag correction for a cone beam CT system.

Validation of automatic segmentation of ribs for NTCP modeling.

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30.

Crizotinib-induced fatal fulminant liver failure.

ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy.

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08).

Fractures of thoracic vertebrae in patients with locally advanced non-small cell lung carcinoma treated with intensity modulated radiotherapy.

Strategies to target drugs to gliomas and CNS metastases of solid tumors.

Dynamic CT perfusion image data compression for efficient parallel processing.

Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer.

Differential analysis of local and regional failure in locally advanced non-small cell lung cancer patients treated with concurrent chemoradiotherapy.

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.

Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.

Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation.

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

Genetic predisposition to ductal carcinoma in situ of the breast.

First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors.

Neurobiological changes by cytotoxic agents in mice.

Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.

Liquid chromatography-tandem mass spectrometric assay for the tyrosine kinase inhibitor afatinib in mouse plasma using salting-out liquid-liquid extraction.

Touch, act and go: landing and operating on nucleosomes.

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

Scenario drafting for early technology assessment of next generation sequencing in clinical oncology.

Exceptions to the rule of informed consent for research with an intervention.

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.

HELB Is a Feedback Inhibitor of DNA End Resection.

Enterovirus D68 receptor requirements unveiled by haploid genetics.

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers.

Renal function, body surface area, and age are associated with risk of early-onset fluoropyrimidine-associated toxicity in patients treated with capecitabine-based anticancer regimens in daily clinical care.

Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model.

The conserved molecular machinery in DNA mismatch repair enzyme structures.

Perioperative treatment and radical cystectomy for bladder cancer--a population based trend analysis of 10,338 patients in the Netherlands.

Cytoreduction and hyperthermic intraperitoneal chemotherapy: The learning curve reassessed.

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

Neoadjuvant induction dose-dense MVAC for muscle invasive bladder cancer: efficacy and safety compared with classic MVAC and gemcitabine/cisplatin.

CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.

Systemic inflammation: Cancer's long-distance reach to maximize metastasis.

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

Correlates of physical activity among colorectal cancer survivors: results from the longitudinal population-based profiles registry.

Does rapid genetic counseling and testing in newly diagnosed breast cancer patients cause additional psychosocial distress? results from a randomized clinical trial.

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