Publications

Acta crystallographica. Section D, Biological crystallography

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

01-11-2015

European journal of cancer (Oxford, England : 1990)

The influence of prior novel androgen receptor targeted therapy on the efficacy of cabazitaxel in men with metastatic castration-resistant prostate cancer.

01-11-2015

EMBO molecular medicine

Androgen receptor profiling predicts prostate cancer outcome.

01-11-2015

Nature genetics

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

01-11-2015

Nature protocols

Using the GEMM-ESC strategy to study gene function in mouse models.

01-11-2015

The Journal of allergy and clinical immunology

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency.

01-11-2015

European journal of cancer (Oxford, England : 1990)

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.

01-11-2015

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.

01-11-2015

Cell cycle (Georgetown, Tex.)

Tumor heterogeneity-induced signaling regulates SCLC metastasis.

29-10-2015

Frontiers in immunology

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.

27-10-2015

Proceedings of the National Academy of Sciences of the United States of America

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

27-10-2015

Journal of cell science

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

15-10-2015

International journal of cancer

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

15-10-2015

Journal of cell science

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

15-10-2015

Science (New York, N.Y.)

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

09-10-2015

Biomarkers in medicine

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

07-10-2015

Mobile genetic elements

Applications of DNA integrating elements: Facing the bias bully.

07-10-2015

Cell reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

06-10-2015

Molecular pharmaceutics

P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice.

05-10-2015

Oncogenesis

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

05-10-2015

Breast cancer research : BCR

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

03-10-2015

Journal of proteome research

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

02-10-2015

Molecular oncology

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

01-10-2015

Investigational new drugs

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

01-10-2015

Cancer research

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

01-10-2015

Scientific reports

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

01-10-2015

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4'‑des-methyl and cephalotaxine metabolites in human plasma and urine.

01-10-2015

Bioinformatics (Oxford, England)

xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.

01-10-2015

Gynecologic oncology

Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies.

01-10-2015

Cancer immunology, immunotherapy : CII

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma.

01-10-2015

European journal of nuclear medicine and molecular imaging

Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

01-10-2015

Immunology and cell biology

The importance of co-stimulation in the orchestration of T helper cell differentiation.

01-10-2015

European journal of nuclear medicine and molecular imaging

Fluorescent radiocolloids: are hybrid tracers the future for lymphatic mapping?

01-10-2015

European journal of nuclear medicine and molecular imaging

First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

01-10-2015

Nature reviews. Clinical oncology

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

01-10-2015

Journal of cancer research and clinical oncology

Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma.

01-10-2015

Annals of oncology : official journal of the European Society for Medical Oncology

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

01-10-2015

International journal of urology : official journal of the Japanese Urological Association

Advances in sentinel node dissection in prostate cancer from a technical perspective.

01-10-2015

Clinical cancer research : an official journal of the American Association for Cancer Research

Translating Pembrolizumab to Clinical Practice: Speak Immunology and Learn Fast!

01-10-2015

Cell reports

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.

29-09-2015

Cell

Genome-wide maps of nuclear lamina interactions in single human cells.

24-09-2015

Oncogene

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

24-09-2015

Oncotarget

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.

22-09-2015

Chinese journal of cancer

A multilevel pan-cancer map links gene mutations to cancer hallmarks.

14-09-2015

Implementation science : IS

Study protocol: an evaluation of the effectiveness, experiences and costs of a patient-directed strategy compared with a multi-faceted strategy to implement physical cancer rehabilitation programmes for cancer survivors in a European healthcare system; a controlled before and after study.

07-09-2015

BMC cancer

The value of completion axillary treatment in sentinel node positive breast cancer patients undergoing a mastectomy: a Dutch randomized controlled multicentre trial (BOOG 2013-07).

03-09-2015

Familial cancer

Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study.

01-09-2015

Journal of the National Cancer Institute

Response.

01-09-2015

Ophthalmology

Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma.

01-09-2015

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Cost-effectiveness of heat and moisture exchangers compared to usual care for pulmonary rehabilitation after total laryngectomy in Poland.

01-09-2015