Publications

Cell

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

08-08-2019

Breast cancer research : BCR

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

07-08-2019

Nature

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

01-08-2019

Pediatric blood & cancer

The involvement of primary care physicians in care for childhood cancer survivors.

01-08-2019

Breast (Edinburgh, Scotland)

Utility of diagnostic breast excision biopsies during two decades of screening mammography.

01-08-2019

Journal of neuroendocrinology

Identification of mineralocorticoid receptor target genes in the mouse hippocampus.

01-08-2019

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology.

01-08-2019

Analytical and bioanalytical chemistry

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.

01-08-2019

Pharmacological research

Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

01-08-2019

Breast cancer research and treatment

Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival.

01-08-2019

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence.

01-08-2019

JACC. Cardiovascular imaging

State-of-the-Art Deep Learning in Cardiovascular Image Analysis.

01-08-2019

Current opinion in chemical biology

Visualizing transcription: key to understanding gene expression dynamics.

01-08-2019

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis.

01-08-2019

European journal of nuclear medicine and molecular imaging

Lesion detection by [⁸⁹Zr]Zr-DFO-girentuximab and [¹⁸F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

01-08-2019

Experimental hematology

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche.

01-08-2019

Genetics in medicine : official journal of the American College of Medical Genetics

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.

01-08-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Physical problems, functional limitations, and preferences for physical therapist-guided exercise programs among Dutch patients with metastatic breast cancer: a mixed methods study.

01-08-2019

British journal of haematology

Setting up a national infrastructure for survivorship care after treatment for Hodgkin lymphoma.

01-08-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

01-08-2019

British journal of clinical pharmacology

Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.

01-08-2019

Oral oncology

Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer.

01-08-2019

Lung cancer (Amsterdam, Netherlands)

Variation in the time to treatment for stage III and IV non-small cell lung cancer patients for hospitals in the Netherlands.

01-08-2019

Expert review of medical devices

Recent advances in nuclear and hybrid detection modalities for image-guided surgery.

01-08-2019

British journal of cancer

Ductal carcinoma in situ: to treat or not to treat, that is the question.

01-08-2019

European radiology

Quantitative 3-T multi-parametric MRI and step-section pathology of recurrent prostate cancer patients after radiation therapy.

01-08-2019

Annals of surgery

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

01-08-2019

BMJ open

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

27-07-2019

Cell

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.

25-07-2019

Blood advances

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

23-07-2019

Nederlands tijdschrift voor geneeskunde

[Care for adolescents and young adults with cancer; the role of a national platform].

23-07-2019

Cancers

Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

18-07-2019

Bioinformatics (Oxford, England)

PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors.

15-07-2019

Journal for immunotherapy of cancer

Transgenerational transfer of gene-modified T cells.

15-07-2019

The EMBO journal

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

15-07-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

15-07-2019

Sarcoma

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

10-07-2019

BMC cancer

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy.

03-07-2019

Journal of the National Cancer Institute

The Influence of Adjuvant Systemic Regimens on Contralateral Breast Cancer Risk and Receptor Subtype.

01-07-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.

01-07-2019

Nature medicine

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

01-07-2019

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

01-07-2019

Neonatology

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

01-07-2019

Immuno-oncology technology

A user's perspective on GeoMx^TM digital spatial profiling.

01-07-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.

01-07-2019

British journal of cancer

Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

01-07-2019

Journal of magnetic resonance imaging : JMRI

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

01-07-2019

Physics and imaging in radiation oncology

Imaging for radiation treatment planning and monitoring in prostate Cancer: Precision, personalization, individualization of therapy.

01-07-2019

Seminars in radiation oncology

Adaptive Radiotherapy for Anatomical Changes.

01-07-2019

International journal of cancer

Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.

01-07-2019

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

The involvement of primary care physicians in care for childhood cancer survivors.

Utility of diagnostic breast excision biopsies during two decades of screening mammography.

Identification of mineralocorticoid receptor target genes in the mouse hippocampus.

Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology.

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.

Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival.

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence.

State-of-the-Art Deep Learning in Cardiovascular Image Analysis.

Visualizing transcription: key to understanding gene expression dynamics.

Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis.

Lesion detection by [89Zr]Zr-DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche.

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.

Physical problems, functional limitations, and preferences for physical therapist-guided exercise programs among Dutch patients with metastatic breast cancer: a mixed methods study.

Setting up a national infrastructure for survivorship care after treatment for Hodgkin lymphoma.

Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.

Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer.

Variation in the time to treatment for stage III and IV non-small cell lung cancer patients for hospitals in the Netherlands.

Recent advances in nuclear and hybrid detection modalities for image-guided surgery.

Ductal carcinoma in situ: to treat or not to treat, that is the question.

Quantitative 3-T multi-parametric MRI and step-section pathology of recurrent prostate cancer patients after radiation therapy.

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

[Care for adolescents and young adults with cancer; the role of a national platform].

Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors.

Transgenerational transfer of gene-modified T cells.

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy.

The Influence of Adjuvant Systemic Regimens on Contralateral Breast Cancer Risk and Receptor Subtype.

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

A user's perspective on GeoMxTM digital spatial profiling.

Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.

Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

Imaging for radiation treatment planning and monitoring in prostate Cancer: Precision, personalization, individualization of therapy.

Adaptive Radiotherapy for Anatomical Changes.

Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.

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Lesion detection by [⁸⁹Zr]Zr-DFO-girentuximab and [¹⁸F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

A user's perspective on GeoMx^TM digital spatial profiling.