Publications

EMBO reports

PHF6 promotes non-homologous end joining and G2 checkpoint recovery.

07-01-2020

Nature

The structural basis for cohesin–CTCF-anchored loops

06-01-2020

Inflammatory bowel diseases

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas.

06-01-2020

International journal of pharmaceutics

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554).

05-01-2020

Journal of pharmaceutical and biomedical analysis

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry.

05-01-2020

European journal of cancer care

The "Psychosocial Aspects in Hereditary Cancer" questionnaire in women attending breast cancer genetic clinics: Psychometric validation across French-, German- and Spanish-language versions.

01-01-2020

British journal of clinical pharmacology

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen.

01-01-2020

Nature protocols

Tumor organoid-T-cell coculture systems.

01-01-2020

Nature cancer

A roadmap for the next decade in cancer research.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Cognitive behavioral therapy or graded exercise therapy compared with usual care for severe fatigue in patients with advanced cancer during treatment: a randomized controlled trial.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Diffusion-weighted MRI with ADC mapping for response prediction and assessment of oesophageal cancer: A systematic review.

01-01-2020

Maturitas

Internet-based cognitive behavioral therapy aimed at alleviating treatment-induced menopausal symptoms in breast cancer survivors: Moderators and mediators of treatment effects.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Multicenter randomized controlled trial to evaluate the efficacy and tolerability of frozen gloves for the prevention of chemotherapy-induced peripheral neuropathy.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Predicting and implications of target volume changes of brain metastases during fractionated stereotactic radiosurgery.

01-01-2020

Nature

B cells and tertiary lymphoid structures promote immunotherapy response.

01-01-2020

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Trending: Radioactive and Fluorescent Bimodal/Hybrid Tracers as Multiplexing Solutions for Surgical Guidance.

01-01-2020

Biology open

Comparative interactomics analysis reveals potential regulators of α6β4 distribution in keratinocytes.

01-01-2020

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Predictors for Autoimmune Cytopenias after Allogeneic Hematopoietic Cell Transplantation in Children.

01-01-2020

Journal of the National Cancer Institute

Quality of Life During Palliative Systemic Therapy for Esophagogastric Cancer: Systematic Review and Meta-Analysis.

01-01-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas.

01-01-2020

International journal of radiation oncology, biology, physics

Response to Preoperative Radiation Therapy in Relation to Gene Expression Patterns in Breast Cancer Patients.

01-01-2020

The Lancet. Oncology

Role of eHealth application Oncokompas in supporting self-management of symptoms and health-related quality of life in cancer survivors: a randomised, controlled trial.

01-01-2020

European journal of immunology

High-throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Differences between planned and delivered dose for head and neck cancer, and their consequences for normal tissue complication probability and treatment adaptation.

01-01-2020

European journal of cancer (Oxford, England : 1990)

A nationwide cohort study on treatment and survival in patients with malignant peripheral nerve sheath tumours.

01-01-2020

European radiology

Long-term imaging characteristics of clinical complete responders during watch-and-wait for rectal cancer-an evaluation of over 1500 MRIs.

01-01-2020

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Cytomegalovirus in Steroid-Refractory Immune Checkpoint Inhibition-Related Colitis.

01-01-2020

European journal of cancer (Oxford, England : 1990)

Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma receiving dabrafenib monotherapy: Analysis from phase 2 and 3 clinical trials.

01-01-2020

Journal of cell science

A genetic interaction map centered on cohesin reveals auxiliary factors in sister chromatid cohesion.

01-01-2020

Medical physics

LDeform: Longitudinal deformation analysis for adaptive radiotherapy of lung cancer.

01-01-2020

Biomedical chromatography : BMC

A review of the bioanalytical methods for the quantitative determination of capecitabine and its metabolites in biological matrices.

01-01-2020

American heart journal

Diagnostic tools for early detection of cardiac dysfunction in childhood cancer survivors: Methodological aspects of the Dutch late effects after childhood cancer (LATER) cardiology study.

01-01-2020

Development (Cambridge, England)

Laminin-binding integrins are essential for the maintenance of functional mammary secretory epithelium in lactation.

01-01-2020

The Lancet. Oncology

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial.

01-01-2020

Journal of clinical epidemiology

Thresholds for clinical importance were defined for the European Organisation for Research and Treatment of Cancer Computer Adaptive Testing Core-an adaptive measure of core quality of life domains in oncology clinical practice and research.

01-01-2020

Clinical and translational radiation oncology

High versus low dose Stereotactic Body Radiation Therapy for hepatic metastases.

01-01-2020

Trends in biochemical sciences

Deciphering Gene Regulation Using Massively Parallel Reporter Assays.

01-01-2020

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Disease course after the first recurrence of head and neck squamous cell carcinoma following (chemo)radiation.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Immuno-radiotherapy with cetuximab and avelumab for advanced stage head and neck squamous cell carcinoma: Results from a phase-I trial.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

SBRT combined with concurrent chemoradiation in stage III NSCLC: Feasibility study of the phase I Hybrid trial.

01-01-2020

Clinical oncology (Royal College of Radiologists (Great Britain))

Embryonal and Alveolar Rhabdomyosarcoma in Adults: Real-Life Data From a Tertiary Sarcoma Centre.

01-01-2020

Journal of cell science

Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation.

01-01-2020

Future oncology (London, England)

ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

01-01-2020

Biomedical chromatography : BMC

Bioanalytical LC-MS/MS validation of therapeutic drug monitoring assays in oncology.

01-01-2020

Nature genetics

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

01-01-2020

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Prostate-Specific Membrane Antigen-Guided Surgery.

01-01-2020

Pharmaceutical research

Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.

26-12-2019

Breast cancer research : BCR

Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer.

26-12-2019

Proceedings of the National Academy of Sciences of the United States of America

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.

26-12-2019