Publications

Fluids and barriers of the CNS

ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain.

05-08-2024

International journal of health policy and management

All Hands on Deck. Transforming the Health System Requires Innovation, Through Individual- and Diffusion Efforts Comment on "Employee-Driven Innovation in Health Organizations: Insights From a Scoping Review".

05-08-2024

Physics in medicine and biology

Enhancing the reliability of deep learning-based head and neck tumour segmentation using uncertainty estimation with multi-modal images.

05-08-2024

Journal of cancer survivorship : research and practice

Eight-year follow-up of patient-reported outcomes in patients with breast cancer participating in exercise studies during chemotherapy.

05-08-2024

Head & neck

The association between skeletal muscle mass and sensorineural hearing loss upon cisplatin-based chemoradiotherapy in patients with head and neck squamous cell carcinoma.

02-08-2024

Cancer discovery

Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.

02-08-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma.

01-08-2024

Journal of cancer survivorship : research and practice

Dutch prostate cancer patients' views about exercise and experience with exercise advice: a national survey.

01-08-2024

Gynecologic oncology

Long-term outcome of high-grade serous carcinoma established in risk-reducing salpingo-oophorectomy specimens in asymptomatic BRCA1/2 germline pathogenic variant carriers.

01-08-2024

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Feasibility, reliability and satisfaction of (automated) capillary carcinoembryonic antigen measurements for future home-based blood sampling: the prospective CASA-I study.

01-08-2024

European journal of cancer (Oxford, England : 1990)

Prognostic value of total tumor volume in patients with colorectal liver metastases: A secondary analysis of the randomized CAIRO5 trial with external cohort validation.

01-08-2024

Journal of surgical oncology

The prediagnostic general practitioner care of sarcoma patients: A real-world data study.

01-08-2024

JAMA oncology

Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

01-08-2024

Nature genetics

Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

01-08-2024

Nature

Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy.

01-08-2024

Nature

Author Correction: Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.

01-08-2024

JAMA oncology

Current Management of Desmoid Tumors: A Review.

01-08-2024

Cancer research

Case-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.

01-08-2024

Key

Clinical nuclear medicine

Baseline and on Treatment Biodistribution Variability of 18 F-FLT Uptake in Patients With Advanced Melanoma: Brief Communication.

01-08-2024

Journal of pharmaceutical and biomedical analysis

Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood.

01-08-2024

European journal of cancer (Oxford, England : 1990)

EBCC-14 manifesto: Addressing disparities in access to innovation for patients with metastatic breast cancer across Europe.

01-08-2024

Cancer medicine

The role of genetic variants in the prediction of hearing loss due to cisplatin chemoradiotherapy.

01-08-2024

JAMA network open

Long-Term Survival in Patients With Advanced Melanoma.

01-08-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The association of cognitive coping style with patient preferences in a patient-led follow-up study among colorectal cancer survivors.

01-08-2024

Clinical pharmacokinetics

Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease.

01-08-2024

Familial cancer

Attitudes toward genetic testing, family planning and preimplantation genetic testing in families with a germline CDKN2A pathogenic variant.

01-08-2024

European journal of nuclear medicine and molecular imaging

Delphi consensus project on prostate-specific membrane antigen (PSMA)-targeted surgery-outcomes from an international multidisciplinary panel.

01-08-2024

Therapeutic drug monitoring

Analytical Validation of a Volumetric Absorptive Microsampling Method for Therapeutic Drug Monitoring of the Oral Targeted Anticancer Agents, Abiraterone, Alectinib, Cabozantinib, Imatinib, Olaparib, and Sunitinib, and Metabolites.

01-08-2024

Nature genetics

Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.

01-08-2024

The Laryngoscope

Decisional Conflict in Patients with Advanced Laryngeal Carcinoma: A Multicenter Study.

01-08-2024

Gynecologic oncology

Preferences and considerations for interval cytoreductive surgery in advanced ovarian cancer: The patient's perspective.

01-08-2024

European journal of cancer (Oxford, England : 1990)

Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma.

01-08-2024

Journal of pharmaceutical and biomedical analysis

ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid.

01-08-2024

British journal of cancer

Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

01-08-2024

European journal of cancer (Oxford, England : 1990)

Understanding quality of life issues in patients with advanced melanoma: Phase 1 and 2 in the development of the EORTC advanced melanoma module.

01-08-2024

JAMA network open

Patient- vs Physician-Initiated Response to Symptom Monitoring and Health-Related Quality of Life: The SYMPRO-Lung Cluster Randomized Trial.

01-08-2024

Nature genetics

Competition shapes the landscape of X-chromosome-linked genetic diversity.

01-08-2024

PloS one

Head-to-head comparison of composite and individual biomarkers to predict clinical benefit to PD-1 blockade in non-small cell lung cancer.

31-07-2024

Nature reviews. Cancer

Rational combination of cancer therapies with PD1 axis blockade.

30-07-2024

Nature protocols

Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq.

30-07-2024

Nature communications

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

29-07-2024

PloS one

Head and Neck Paraganglioma (HNPGL) Registry: A study protocol for prospective data collection in patients with Head and Neck Paragangliomas.

26-07-2024

bioRxiv : the preprint server for biology

Optimized reporters for multiplexed detection of transcription factor activity.

26-07-2024

Cancers

Adverse Events in Anti-PD-1-Treated Adjuvant and First-Line Advanced Melanoma Patients.

26-07-2024

BMC cancer

Pembrolizumab plus either epacadostat or placebo for cisplatin-ineligible urothelial carcinoma: results from the ECHO-307/KEYNOTE-672 study.

25-07-2024

Journal of cancer survivorship : research and practice

Prevalence and determinants of sleep problems in cancer survivors compared to a normative population: a PROFILES registry study.

24-07-2024

Nature communications

Single gene analysis in yeast suggests nonequilibrium regulatory dynamics for transcription.

23-07-2024

Current biology : CB

Cell biology: Converging paths to cohesion.

22-07-2024

Journal of medical genetics

Validation of the BOADICEA model in a prospective cohort of BRCA1/2 pathogenic variant carriers.

19-07-2024

iScience

"Radical" differences between two FLIM microscopes affect interpretation of cell signaling dynamics.

19-07-2024