Publications

Scientific reports

Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy.

23-11-2016

ESMO open

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

16-11-2016

Cardio-oncology (London, England)

Cardiovascular co-morbidity in cancer patients: the role of psychological distress.

15-11-2016

Scientific reports

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.

15-11-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab.

15-11-2016

eLife

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

15-11-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Focusing on Core Patient-Reported Outcomes in Cancer Clinical Trials-Letter.

15-11-2016

Breast cancer research : BCR

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women.

11-11-2016

Cell metabolism

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

08-11-2016

Oncotarget

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.

08-11-2016

BMC cancer

A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation?

08-11-2016

Cold Spring Harbor symposia on quantitative biology

Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.

07-11-2016

EMBO reports

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

01-11-2016

Acta oncologica (Stockholm, Sweden)

Prospective Dutch colorectal cancer cohort: an infrastructure for long-term observational, prognostic, predictive and (randomized) intervention research.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

An MRI-based mid-ventilation approach for radiotherapy of the liver.

01-11-2016

International journal of radiation oncology, biology, physics

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis.

01-11-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

01-11-2016

AJR. American journal of roentgenology

Diagnostic Accuracy of CT for Local Staging of Colon Cancer: A Systematic Review and Meta-Analysis.

01-11-2016

International journal of radiation oncology, biology, physics

Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.

01-11-2016

Journal of the National Cancer Institute

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

01-11-2016

Lasers in surgery and medicine

In vivo tumor identification of colorectal liver metastases with diffuse reflectance and fluorescence spectroscopy.

01-11-2016

European journal of cancer (Oxford, England : 1990)

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

01-11-2016

JAMA oncology

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

01-11-2016

European journal of cell biology

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

01-11-2016

European urology

The Effect of Salvage Radiotherapy and its Timing on the Health-related Quality of Life of Prostate Cancer Patients.

01-11-2016

Cancer treatment reviews

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Consensus opinion on MRI simulation for external beam radiation treatment planning.

01-11-2016

Cancer treatment reviews

Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity - Ready for clinical practice?

01-11-2016

Clinical pharmacokinetics

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

01-11-2016

Urologic oncology

Prostate cancer survivors with a passive role preference in treatment decision-making are less satisfied with information received: Results from the PROFILES registry.

01-11-2016

Frontiers in oncology

The MRI-Linear Accelerator Consortium: Evidence-Based Clinical Introduction of an Innovation in Radiation Oncology Connecting Researchers, Methodology, Data Collection, Quality Assurance, and Technical Development.

30-10-2016

Methods in molecular biology (Clifton, N.J.)

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

28-10-2016

Epigenetics & chromatin

High-throughput assessment of context-dependent effects of chromatin proteins.

26-10-2016

Journal of pharmaceutical and biomedical analysis

Recent developments in the chromatographic bioanalysis of approved kinase inhibitor drugs in oncology.

25-10-2016

JAMA

Breast Cancer Risk After Ovarian Stimulation for In Vitro Fertilization-Reply.

25-10-2016

Oncotarget

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

25-10-2016

BMC systems biology

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

21-10-2016

Breast cancer research : BCR

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

18-10-2016

The Journal of experimental medicine

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

17-10-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

15-10-2016

Cancer research

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

15-10-2016

Oncotarget

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

11-10-2016

Cancer cell

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

10-10-2016

Cancer cell

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

10-10-2016

Journal of controlled release : official journal of the Controlled Release Society

Inherent formulation issues of kinase inhibitors.

10-10-2016

Oncogene

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

06-10-2016

American journal of human genetics

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

06-10-2016

Breast cancer research : BCR

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

03-10-2016