Publications

International journal of pharmaceutics

Improving the solubility of nilotinib through novel spray-dried solid dispersions.

30-08-2017

ESMO open

Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers.

30-08-2017

eLife

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.

29-08-2017

Cell reports

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

29-08-2017

Breast cancer research : BCR

The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting.

25-08-2017

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Impact of 70-Gene Signature Use on Adjuvant Chemotherapy Decisions in Patients With Estrogen Receptor-Positive Early Breast Cancer: Results of a Prospective Cohort Study.

20-08-2017

EJNMMI research

Introducing navigation during melanoma-related sentinel lymph node procedures in the head-and-neck region.

17-08-2017

Science translational medicine

Direct detection of early-stage cancers using circulating tumor DNA.

16-08-2017

Oncotarget

Nuclear receptor NR4A1 is a tumor suppressor down-regulated in triple-negative breast cancer.

15-08-2017

Oncotarget

Loss of steroid hormone receptors is common in malignant pleural and peritoneal effusions of breast cancer patients treated with endocrine therapy.

15-08-2017

Proceedings of the National Academy of Sciences of the United States of America

DNA damage tolerance in hematopoietic stem and progenitor cells in mice.

15-08-2017

Journal of medical Internet research

"Am I normal?" The Wishes of Patients With Lymphoma to Compare Their Patient-Reported Outcomes With Those of Their Peers.

15-08-2017

Oncotarget

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study.

15-08-2017

Toxicology and applied pharmacology

Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1.

15-08-2017

Nature biotechnology

Characterization of noncoding regulatory DNA in the human genome.

08-08-2017

JMIR cancer

Supporting Lung Cancer Patients With an Interactive Patient Portal: Feasibility Study.

08-08-2017

BMC public health

Cancer and heart attack survivors' expectations of employment status: results from the English Longitudinal Study of Ageing.

07-08-2017

Revista espanola de medicina nuclear e imagen molecular

From interventionist imaging to intraoperative guidance: New perspectives by combining advanced tools and navigation with radio-guided surgery.

07-08-2017

PLoS genetics

Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.

01-08-2017

Virchows Archiv : an international journal of pathology

Early detection: the impact of genomics.

01-08-2017

Investigational new drugs

Metabolism and disposition of the anticancer quinolone derivative vosaroxin, a novel inhibitor of topoisomerase II.

01-08-2017

DNA repair

Histone ubiquitination in the DNA damage response.

01-08-2017

Urologic oncology

Prevalence and correlates of mental health problems in prostate cancer survivors: A case-control study comparing survivors with general population peers.

01-08-2017

Drugs

Neoadjuvant Therapy for Breast Cancer: Established Concepts and Emerging Strategies.

01-08-2017

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Erratum to: Using a discrete choice experiment to value the QLU-C10D: feasibility and sensitivity to presentation format.

01-08-2017

Journal of the National Cancer Institute

Breast Cancer Survival of BRCA1/BRCA2 Mutation Carriers in a Hospital-Based Cohort of Young Women.

01-08-2017

Urologic oncology

Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

01-08-2017

BJU international

Sentinel node biopsy for prostate cancer: report from a consensus panel meeting.

01-08-2017

Chromosoma

Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation.

01-08-2017

EMBO molecular medicine

Phenotypic diversity drives paracrine drug tolerance.

01-08-2017

Nature genetics

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.

01-08-2017

Oral oncology

Prognostic role of tumor infiltrating lymphocytes in EBV positive and EBV negative nasopharyngeal carcinoma.

01-08-2017

Primary care diabetes

Trends in breast cancer incidence among women with type-2 diabetes in British general practice.

01-08-2017

Journal of cachexia, sarcopenia and muscle

Psoas muscle area is not representative of total skeletal muscle area in the assessment of sarcopenia in ovarian cancer.

01-08-2017

International journal of cancer

Why is colon cancer survival improving by time? A nationwide survival analysis spanning 35 years.

01-08-2017

British journal of cancer

Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors.

25-07-2017

F1000Research

GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes.

20-07-2017

American journal of nuclear medicine and molecular imaging

Multispectral fluorescence guided surgery; a feasibility study in a phantom using a clinical-grade laparoscopic camera system.

20-07-2017

Scientific reports

Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer.

17-07-2017

Physics in medicine and biology

A back-projection algorithm in the presence of an extra attenuating medium: towards EPID dosimetry for the MR-Linac.

17-07-2017

Nature communications

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

17-07-2017

Cancer research

Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.

15-07-2017

Cancer research

A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer.

15-07-2017

International journal of radiation oncology, biology, physics

Stereotactic Body Radiation Therapy in Octo- and Nonagenarians for the Treatment of Early-Stage Lung Cancer.

15-07-2017

The EMBO journal

ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

14-07-2017

Scientific reports

Deep Learning for Fully-Automated Localization and Segmentation of Rectal Cancer on Multiparametric MR.

13-07-2017

JMIR research protocols

Treatment of Peritoneal Dissemination in Stomach Cancer Patients With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Rationale and Design of the PERISCOPE Study.

13-07-2017

Nature communications

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors.

13-07-2017

British journal of cancer

Radiation-associated breast cancer and gonadal hormone exposure: a report from the Childhood Cancer Survivor Study.

11-07-2017

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-Term Risk of Subsequent Malignant Neoplasms After Treatment of Childhood Cancer in the DCOG LATER Study Cohort: Role of Chemotherapy.

10-07-2017