Publications

Cancer research

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

15-03-2004

The Journal of biological chemistry

High incidence of thymic epithelial tumors in E2F2 transgenic mice.

12-03-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the novel anticancer drug ABT-518, a matrix metalloproteinase inhibitor, plus the screening of six metabolites in human plasma using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

01-03-2004

Journal of mass spectrometry : JMS

Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N"-triethylenethiophosphoramide (thiotepa) and N,N',N"-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

01-03-2004

Molecular biology of the cell

Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.

01-03-2004

British journal of cancer

N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx.

23-02-2004

Journal of immunology (Baltimore, Md. : 1950)

The impact of self-tolerance on the polyclonal CD8+ T cell repertoire.

15-02-2004

Cancer chemotherapy and pharmacology

The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice.

01-02-2004

Medical physics

Leaf trajectory verification during dynamic intensity modulated radiotherapy using an amorphous silicon flat panel imager.

01-02-2004

Cancer causes & control : CCC

A cohort study of cancer mortality among Biology Research Laboratory workers in The Netherlands.

01-02-2004

Medical physics

Dose-response and ghosting effects of an amorphous silicon electronic portal imaging device.

01-02-2004

Clinical pharmacokinetics

Population pharmacokinetics and pharmacodynamics of mitomycin during intraoperative hyperthermic intraperitoneal chemotherapy.

30-01-2004

Genome research

A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization

01-01-2004

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.

01-01-2004

Handbook of experimental pharmacology

Hemidesmosomes: molecular organization and their importance for cell adhesion and disease.

01-01-2004

Analytical biochemistry

Development and validation of a method to determine the unbound paclitaxel fraction in human plasma.

01-01-2004

The Journal of pharmacology and experimental therapeutics

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

01-01-2004

Radiation research

Identification of differentially expressed genes in mouse kidney after irradiation using microarray analysis.

01-01-2004

Breast cancer research and treatment

Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers.

01-01-2004

Proceedings of the National Academy of Sciences of the United States of America

Gene expression profiles of primary breast tumors maintained in distant metastases.

23-12-2003

Journal of chromatography. A

Development and validation of a liquid chromatography-ultraviolet absorbance detection assay using derivatisation for the novel marine anticancer agent ES-285 x HCl [(2S,3R)-2-amino-3-octadecanol hydrochloride] and its pharmaceutical dosage form.

12-12-2003

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of zosuquidar trihydrochloride (LY335979) in small volumes of human and murine plasma by ion-pairing reversed-phase high-performance liquid chromatography.

05-12-2003

Apoptosis : an international journal on programmed cell death

The anti-cancer drug etoposide can induce caspase-8 processing and apoptosis in the absence of CD95 receptor-ligand interaction.

04-12-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

01-12-2003

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Thallium-201-chloride scintigraphy in staging and monitoring radiotherapy response in follicular lymphoma patients.

01-12-2003

Genes & development

Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location.

15-11-2003

The Journal of experimental medicine

CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool.

03-11-2003

British journal of cancer

P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo.

03-11-2003

Cancer research

The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice.

01-11-2003

Molecular and cellular biology

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.

01-11-2003

The Journal of biological chemistry

Calcium signaling regulates translocation and activation of Rac.

10-10-2003

Cancer research

The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

01-10-2003

Nature reviews. Cancer

New tools for functional mammalian cancer genetics.

01-10-2003

Drug development and industrial pharmacy

Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280.

01-10-2003

Cancer cell

The tumor-suppressive functions of the human INK4A locus.

01-10-2003

Molecular biology of the cell

Specificity of binding of the plectin actin-binding domain to beta4 integrin.

01-10-2003

Cell cycle (Georgetown, Tex.)

The survivin/Aurora B complex: its role in coordinating tension and attachment.

25-09-2003

The Biochemical journal

Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.

15-09-2003

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term cause-specific mortality of patients treated for Hodgkin's disease.

15-09-2003

Clinical cancer research : an official journal of the American Association for Cancer Research

Randomized phase I clinical and pharmacologic study of weekly versus twice-weekly dose-intensive cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

01-09-2003

European journal of cancer (Oxford, England : 1990)

Improved survival of patients with rectal cancer since 1980: a population-based study.

01-09-2003

Cancer cell

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model.

01-09-2003

Human reproduction (Oxford, England)

Risk of benign gynaecological diseases and hormonal disorders according to responsiveness to ovarian stimulation in IVF: a follow-up study of 8714 women.

01-09-2003

Nucleic acids research

Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates.

15-08-2003

Nature

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.

14-08-2003

Acta oncologica (Stockholm, Sweden)

Psychosocial issues in cancer genetics--current status and future directions.

06-08-2003

Seminars in cancer biology

Ras interference as cancer therapy.

01-08-2003

BioTechniques

Epigenomic profiling using microarrays.

01-08-2003

Anti-cancer drugs

Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin.

01-08-2003

PDA journal of pharmaceutical science and technology

Pharmaceutical quality control of the investigational polymer-conjugated platinum anticancer agent AP 5280.

25-07-2003