Publications

Lancet (London, England)

Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment.

22-06-2024

Nature communications

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

22-06-2024

Nature biotechnology

Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

21-06-2024

iScience

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

21-06-2024

Scientific reports

Cox proportional hazards regression in small studies of predictive biomarkers.

20-06-2024

NPJ digital medicine

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

20-06-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

20-06-2024

Cell reports. Medicine

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

18-06-2024

The British journal of radiology

Imaging in the era of risk-adapted treatment in colon cancer.

18-06-2024

Journal of pharmaceutical and biomedical analysis

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

15-06-2024

Nature communications

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

12-06-2024

Cancer cell

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

10-06-2024

The New England journal of medicine

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

06-06-2024

Molecular cancer

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

04-06-2024

bioRxiv : the preprint server for biology

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

03-06-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

ABCB1 attenuates brain exposure to the KRAS^G12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Common Sense Oncology: Equity, Value, and Outcomes That Matter.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Adoptive Cell Therapy for Solid Tumors: Current Status in Melanoma and Next-Generation Therapies.

01-06-2024

FEBS letters

Decoding microtubule detyrosination: enzyme families, structures, and functional implications.

01-06-2024

Diseases of the colon and rectum

An International Expert-Based Consensus on the Definition of a Clinical Near-Complete Response After Neoadjuvant (Chemo)radiotherapy for Rectal Cancer.

01-06-2024

European radiology

Importance and evolution of split scar sign.

01-06-2024

Journal of biomedical optics

Deformable multi-modal image registration for the correlation between optical measurements and histology images.

01-06-2024

JCO clinical cancer informatics

Improving Diagnosis and Care for Patients With Sarcoma: Do Real-World General Practitioners Data and Prospective Data Collections Have a Place Next to Clinical Trials?

01-06-2024

Advances in radiation oncology

Evaluation of Deep Learning Clinical Target Volumes Auto-Contouring for Magnetic Resonance Imaging-Guided Online Adaptive Treatment of Rectal Cancer.

01-06-2024

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Impact of the new rectal cancer definition on multimodality treatment and interhospital variability: Results from a nationwide cross-sectional study.

01-06-2024

European urology

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.

01-06-2024

European journal of radiology open

Reproducing RECIST lesion selection via machine learning: Insights into intra and inter-radiologist variation.

01-06-2024

Journal of molecular biology

MutL Activates UvrD by Interaction Between the MutL C-terminal Domain and the UvrD 2B Domain.

01-06-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.

01-06-2024

ESMO open

Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes.

01-06-2024

Nature reviews. Molecular cell biology

Seeing transcription in real time.

01-06-2024

Journal of cancer survivorship : research and practice

Subgroups of cognitively affected and unaffected breast cancer survivors after chemotherapy: a data-driven approach.

01-06-2024

Breast (Edinburgh, Scotland)

Radiological, pathological and surgical outcomes after neoadjuvant endocrine treatment in patients with ER-positive/HER2-negative breast cancer with a clinical high risk and a low-risk 70-gene signature.

01-06-2024

Therapeutic drug monitoring

Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication.

01-06-2024

Current opinion in genetics & development

Attraction and disruption: how loop extrusion and compartmentalisation shape the nuclear genome.

01-06-2024

Investigative radiology

How Does Target Lesion Selection Affect RECIST? A Computer Simulation Study.

01-06-2024

Molecular oncology

Academia and society should join forces to make anti-cancer treatments more affordable.

01-06-2024

Oncogene

Molecular mechanisms of non-genetic aberrant peptide production in cancer.

01-06-2024

AJR. American journal of roentgenology

Beyond the AJR: A Breakthrough in the Use of Artificial Intelligence for Mammography in Screening for Breast Cancer.

01-06-2024

The Journal of pathology

Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting.

01-06-2024

Analytical biochemistry

An LC-MS/MS-based method for the simultaneous quantification of melatonin, cortisol and cortisone in saliva.

01-06-2024

Cancer medicine

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors.

01-06-2024

European journal of cancer (Oxford, England : 1990)

European clinical practice guidelines for the definition, diagnosis, and treatment of oligometastatic esophagogastric cancer (OMEC-4).

01-06-2024

Gastroenterology

Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs.

01-06-2024

Journal of genetic counseling

Does a proactive procedure lead to a higher uptake of predictive testing in families with a pathogenic BRCA1/BRCA2 variant? A family cancer clinic evaluation.

01-06-2024

Annals of epidemiology

Strategies to increase survey participation: A randomized controlled study in a population of breast cancer survivors.

01-06-2024

European radiology

Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation.

01-06-2024

Cytotherapy

High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant.

01-06-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment.

01-06-2024

European journal of cancer (Oxford, England : 1990)

Oncological outcomes after a pathological complete response following total neoadjuvant therapy or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial.

01-06-2024