Publications

Investigational new drugs

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.

01-02-2015

Carcinogenesis

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

01-02-2015

Clinical genitourinary cancer

Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer.

01-02-2015

Nature genetics

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

01-02-2015

World journal of surgery

Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy.

01-02-2015

Head & neck

Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy: a systematic review of the literature.

01-02-2015

Oncogene

Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL.

29-01-2015

Ecancermedicalscience

Report from the OECI Oncology Days 2014.

28-01-2015

Journal of translational medicine

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy.

27-01-2015

J Pathol.: The journal of pathology

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

23-01-2015

Science (New York, N.Y.)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

23-01-2015

JMIR research protocols

Development of MijnAVL, an Interactive Portal to Empower Breast and Lung Cancer Survivors: An Iterative, Multi-Stakeholder Approach.

22-01-2015

Oncogene

A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.

22-01-2015

Molecular cell

Transcription initiation determines its end.

22-01-2015

Molecular cell

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

22-01-2015

J Proteome Res.: Journal of proteome research

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer

20-01-2015

Cell reports

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

20-01-2015

Oncoscience

P-gp and taxanes.

17-01-2015

Experimental cell research

Quantitative imaging of focal adhesion dynamics and their regulation by HGF and Rap1 signaling.

15-01-2015

Cancer cell

Biomarkers in cancer immunotherapy.

12-01-2015

American journal of human genetics

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

08-01-2015

British journal of cancer

Increased stomach cancer risk following radiotherapy for testicular cancer.

06-01-2015

International journal of cancer

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

01-01-2015

Antimicrobial agents and chemotherapy

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis.

01-01-2015

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Lymphovascular space invasion and the treatment of stage I endometrioid endometrial cancer.

01-01-2015

Journal of cell science

N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging.

01-01-2015

Nature genetics

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.

01-01-2015

Nucleic acids research

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.

01-01-2015

European journal of cancer (Oxford, England : 1990)

Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative.

01-01-2015

Psychopharmacology

Cognitive impact of cytotoxic agents in mice.

01-01-2015

International immunology

Therapeutic use of anti-CTLA-4 antibodies.

01-01-2015

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

The value of optical coherence tomography in determining surgical margins in squamous cell carcinoma of the vulva: a single-center prospective study.

01-01-2015

European journal of cancer (Oxford, England : 1990)

Increased breast cancer risk in in vitro fertilisation treated women with a multiple pregnancy: a new hypothesis based on historical in vitro fertilisation treatment data.

01-01-2015

Annals of hematology

Impact of active surveillance, chlorambucil, and other therapy on health-related quality of life in patients with CLL/SLL in the Netherlands.

01-01-2015

Human molecular genetics

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

01-01-2015

International journal of radiation oncology, biology, physics

Valvular abnormalities detected by echocardiography in 5-year survivors of childhood cancer: a long-term follow-up study.

01-01-2015

Journal of the International Neuropsychological Society : JINS

Very Late Treatment-Related Alterations in Brain Function of Breast Cancer Survivors.

01-01-2015

Nature medicine

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

01-01-2015

The journal of pathology. Clinical research

Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium.

01-01-2015

Pharmaceutical research

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) restrict oral availability and brain accumulation of the PARP inhibitor rucaparib (AG-014699).

01-01-2015

Menopause (New York, N.Y.)

Cognitive functioning during long-term tamoxifen treatment in postmenopausal women with breast cancer.

01-01-2015

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

01-01-2015

Bioanalysis

Quantifying vemurafenib in dried blood spots using high-performance LC-MS/MS.

23-12-2014

Molecular systems biology

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma.

23-12-2014

Cell death & disease

Suppression of BRCA1 sensitizes cells to proteasome inhibitors.

18-12-2014

Bioanalysis

Determination of tamoxifen and endoxifen in dried blood spots using LC-MS/MS and the effect of coated DBS cards on recovery and matrix effects.

17-12-2014

Nucleic acids research

Easy quantitative assessment of genome editing by sequence trace decomposition.

16-12-2014

Nature communications

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.

15-12-2014

Journal of cell science

CLIC4 regulates cell adhesion and β1 integrin trafficking.

15-12-2014

Cell cycle (Georgetown, Tex.)

Enter the nucleus to exit the cycle.

09-12-2014