Publications

Translational oncology

Monitoring of tumor response to Cisplatin using optical spectroscopy.

01-04-2014

Proceedings of the National Academy of Sciences of the United States of America

Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma.

01-04-2014

Bioanalysis

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

01-04-2014

Cancer discovery

Unlikely suspects identified in neuroblastoma conspiracy.

01-04-2014

The Lancet. Oncology

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

01-04-2014

PLoS genetics

Chromatin landscapes of retroviral and transposon integration profiles.

01-04-2014

European journal of cancer (Oxford, England : 1990)

Risk estimations and treatment decisions in early stage breast cancer: agreement among oncologists and the impact of the 70-gene signature.

01-04-2014

The Lancet. Oncology

Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study.

01-04-2014

PLoS genetics

Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

01-04-2014

Journal of the International Neuropsychological Society : JINS

Systemically treated breast cancer patients and controls: an evaluation of the presence of noncredible performance.

01-04-2014

Clinical pharmacokinetics

Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.

01-04-2014

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the light sensitive survivin suppressant sepantronium bromide (YM155) in mouse plasma.

01-04-2014

BioMed research international

Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy.

29-03-2014

Molecular cell

Uncovering SUMOylation dynamics during cell-cycle progression reveals FoxM1 as a key mitotic SUMO target protein.

20-03-2014

International journal of cancer

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

15-03-2014

Molecular cell

Assessing kinetics from fixed cells reveals activation of the mitotic entry network at the S/G2 transition.

06-03-2014

Nature

Cancer: Inflammation lights the way to metastasis.

06-03-2014

Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

01-03-2014

European urology

A hybrid radioactive and fluorescent tracer for sentinel node biopsy in penile carcinoma as a potential replacement for blue dye.

01-03-2014

Clinical pharmacokinetics

Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study.

01-03-2014

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Association between metformin use and mortality in patients with prostate cancer: explained by confounding by indication?

01-03-2014

Molecular pharmacology

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

01-03-2014

Medical physics

Multi-institutional dosimetric and geometric commissioning of image-guided small animal irradiators.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The course of health-related quality of life in head and neck cancer patients treated with chemoradiation: a prospective cohort study.

01-03-2014

Annals of oncology : official journal of the European Society for Medical Oncology

Long-term responders and survivors on pazopanib for advanced soft tissue sarcomas: subanalysis of two European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62043 and 62072.

01-03-2014

Current opinion in oncology

The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose-response relationship with clinical outcome for lung stereotactic body radiotherapy (SBRT) delivered via online image guidance.

01-03-2014

International journal of radiation oncology, biology, physics

Performance of a nomogram predicting disease-specific survival after an R0 resection for gastric cancer in patients receiving postoperative chemoradiation therapy.

01-03-2014

International journal of radiation oncology, biology, physics

Combined recipe for clinical target volume and planning target volume margins.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Mid-ventilation based PTV margins in Stereotactic Body Radiotherapy (SBRT): a clinical evaluation.

01-03-2014

The Journal of molecular diagnostics : JMD

MammaPrint molecular diagnostics on formalin-fixed, paraffin-embedded tissue.

01-03-2014

Human brain mapping

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy.

01-03-2014

European journal of cancer (Oxford, England : 1990)

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983.

01-03-2014

Cancer letters

Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.

01-03-2014

The Lancet. Oncology

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study.

01-03-2014

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Treatment adherence in concurrent chemoradiation in patients with locally advanced non-small cell lung carcinoma: results of daily intravenous prehydration.

01-03-2014

Cell reports

Determining lineage pathways from cellular barcoding experiments.

27-02-2014

PloS one

Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.

22-02-2014

ACS chemical biology

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection.

21-02-2014

Cell cycle (Georgetown, Tex.)

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

21-02-2014

British journal of cancer

Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity.

18-02-2014

British journal of cancer

The impact of organisational external peer review on colorectal cancer treatment and survival in the Netherlands.

18-02-2014

British journal of cancer

Impact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial.

18-02-2014

Nature communications

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

13-02-2014

Journal of pharmaceutical sciences

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

01-02-2014

Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

01-02-2014

Molecular cancer therapeutics

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

01-02-2014

Current opinion in genetics & development

Finding effective cancer therapies through loss of function genetic screens.

01-02-2014

EMBO reports

RBR E3-ligases at work.

01-02-2014

Breast cancer research and treatment

Long-term impact of the 70-gene signature on breast cancer outcome.

01-02-2014