Publications

Biochemical Society transactions

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.

01-12-2011

Current opinion in cell biology

Mechanisms of integrin activation and trafficking.

01-10-2011

Journal of cell science

Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish.

01-03-2011

The Journal of biological chemistry

EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4.

26-11-2010

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Unique and redundant functions of integrins in the epidermis.

01-11-2010

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

01-06-2010

EMBO reports

Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing.

01-02-2010

Journal of cell science

Integrin alpha3beta1 inhibits directional migration and wound re-epithelialization in the skin.

15-01-2009

Current opinion in cell biology

Regulation of hemidesmosome disassembly by growth factor receptors.

01-10-2008

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

Molecular biology of the cell

Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function.

01-11-2007

Journal of cell science

Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin.

01-10-2007

Molecular biology of the cell

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

01-09-2007

Experimental cell research

Plakins in development and disease.

10-06-2007

Journal of molecular biology

The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.

18-05-2007

Experimental cell research

The regulation of MacMARCKS expression by integrin beta3.

01-04-2007

Cancer research

Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src.

15-03-2007

Journal of cell science

KASH-domain proteins in nuclear migration, anchorage and other processes.

15-12-2006

The Journal of cell biology

Kidney failure in mice lacking the tetraspanin CD151.

09-10-2006

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

01-07-2006

Molecular and cellular biology

Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.

01-04-2006

The Journal of cell biology

The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

05-12-2005

The Journal of cell biology

Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.

05-12-2005

The Journal of biological chemistry

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

10-06-2005

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

01-03-2005

Molecular biology of the cell

Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.

01-03-2004

Handbook of experimental pharmacology

Hemidesmosomes: molecular organization and their importance for cell adhesion and disease.

01-01-2004

The Journal of pathology

Integrins in regulation of tissue development and function.

01-12-2003

Molecular biology of the cell

Specificity of binding of the plectin actin-binding domain to beta4 integrin.

01-10-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

01-07-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003

The Journal of cell biology

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

23-12-2002

Molecular biology of the cell

Dynamics of the alpha6beta4 integrin in keratinocytes.

01-11-2002

Journal of cell science

Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo.

15-03-2002

The Journal of cell biology

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

21-01-2002

The Journal of investigative dermatology

Two different mutations in the cytoplasmic domain of the integrin beta 4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of beta 4 with plectin.

01-12-2001

Journal of cell science

The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin.

01-06-2001

Biochimica et biophysica acta

Structural and functional aspects of filamins.

23-04-2001

The Journal of cell biology

Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression.

25-12-2000

The Journal of cell biology

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

15-05-2000

Journal of cell science

Formation of hemidesmosome-like structures in the absence of ligand binding by the (alpha)6(beta)4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the (beta)4 integrin subunit.

01-03-2000

The Journal of cell biology

Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.

13-12-1999

Journal of cell science

Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene.

01-11-1999

The Journal of cell biology

Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding.

18-10-1999

BioEssays : news and reviews in molecular, cellular and developmental biology

Integrins: alternative splicing as a mechanism to regulate ligand binding and integrin signaling events.

01-06-1999

Matrix biology : journal of the International Society for Matrix Biology

Biology and function of hemidesmosomes.

01-02-1999

The Journal of cell biology

Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.

05-10-1998

Biochemical and biophysical research communications

Genomic organization of the human alpha 3 integrin subunit gene.

30-07-1998

The Journal of cell biology

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

13-07-1998