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commonly used anti-cancer drugs doxorubicin and e toposide. In The Netherlands alone, thousands of patients a year are treated with one of these drugs. But they don't always work well for every patient. The new discovery might help predict whether…
stimulates the patient's immune system to fight cancer. Despite promising results, however, tumor cells are not always sensitive to this treatment. Researchers at the Netherlands Cancer Institute under the supervision of Prof. Daniel Peeper have…
a 'do not eat me' signal. Led by immunologist Ton Schumacher (Netherlands Cancer Institute and Oncode) and Ferenc Scheeren (Leiden University Medical Center), researchers from various research institutes have discovered a new method to inhibit the…
web application ‘Application and Request Tool’ (ART). ART is the online tool for e.g. study registration (human biospecimens IRBm and human data IRBd, or combi IRBdm and IRBb for biobanks), Institutional Review Board (IRB) review, lab logistics,…
receive their PhDs. How do they find their way in to a career in science? A conversation with Iris van ’t Erve , about working, living, and freedom across the ocean.
recurrence This publication is an important miles tone in our knowledge of the treatment for bladder cancer (urothelial carcinoma). Patients with this type of cancer often face a return of their illness after surgery. Treatment with immunotherapy…
tumor - the cancer stem cells - drives a tumor to be invasive and life-threatening.
and Oncode researchers Daniela Thommen and Ton Schumacher and colleagues from Basel may have opened up a new venue for stratifying patients for cancer immunotherapy.
A patient's own immune cells, expanded in to an army of billions of immune cells in a specialized laboratory, can be used as a living drug against metastatic melanoma, an aggressive type of skin cancer, as the TIL trial has shown. The TIL trial, the…
What do Dutch researcher and Oncode Investiga tor Rene Bernards (NKI) and British columnist and podcaster Deborah James have in common? They are both on a mission to fight cancer. Bernards’ ultimate goal is to bring his research findings to the…
in the Department of Radiology, intended to become a trauma surgeon. This was in the days of the Libyan conflict and most of his patients had gunshot injuries or shrapnel wounds. He also received many patients with acute oncologic emergencies this…
Cancer cells that develop resistance to drugs, pay a price for this, by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically. A team of cancer researchers, led by Rene…
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