Chemotherapy induced neuropathy (CIPN) can lead to sensory and motor impairments which impact balance and walking ability, thereby restricting activities of daily life. Currently, therapy options are limited. Biomechanical factors, such as foot loading, variations in anatomy, and local pressure distribution may mediate the effects of CIPN on balance and walking ability.
In this project we aim to better understand the importance of biomechanics in the relationship between CIPN symptoms, disability and quality of life, through elaborate measurements of foot function, walking ability, balance and patient reported outcomes.