Publications

Frontiers in immunology

Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers.

16-10-2019

Pharmaceutical research

Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?

15-10-2019

Methods in molecular biology (Clifton, N.J.)

Epi-ID: Systematic and Direct Screening for Chromatin Regulators in Yeast by Barcode-ChIP-Seq.

12-10-2019

Journal of cell science

Tetraspanin CD151 and integrin α3β1 contribute to the stabilization of integrin α6β4-containing cell-matrix adhesions.

10-10-2019

Nucleic acids research

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

10-10-2019

Science translational medicine

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.

09-10-2019

The EMBO journal

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

04-10-2019

Journal of translational medicine

Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study.

02-10-2019

Breast cancer research and treatment

Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers.

01-10-2019

Cancer letters

Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.

01-10-2019

British journal of clinical pharmacology

Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.

01-10-2019

Molecular aspects of medicine

Circulating biomarkers for early detection and clinical management of colorectal cancer.

01-10-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

The Promise of Neoadjuvant Immunotherapy and Surgery for Cancer Treatment.

01-10-2019

Clinical genitourinary cancer

Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer With a Hepatic Transplant.

01-10-2019

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program.

01-10-2019

Nature

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

01-10-2019

European urology

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer.

01-10-2019

Molecular aspects of medicine

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

01-10-2019

European urology

Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME).

01-10-2019

Journal of community genetics

Correction to: Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

01-10-2019

Physics and imaging in radiation oncology

Geometrical and dosimetric evaluation of breast target volume auto-contouring.

01-10-2019

Endocrine-related cancer

The molecular genetic make-up of male breast cancer.

01-10-2019

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab.

01-10-2019

Journal of physiotherapy

An international perspective on integrating physiotherapists in oncology care.

01-10-2019

Therapeutic drug monitoring

Simultaneous Quantification of Free Adalimumab and Infliximab in Human Plasma Using a Target-Based Sample Purification and Liquid Chromatography-Tandem Mass Spectrometry.

01-10-2019

European journal of immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

01-10-2019

Immuno-oncology technology

The promise of IO and IOTECH.

01-10-2019

Nature genetics

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.

01-10-2019

Clinical genitourinary cancer

Second-Line Cabazitaxel Treatment in Castration-Resistant Prostate Cancer Clinical Trials Compared to Standard of Care in CAPRI: Observational Study in the Netherlands.

01-10-2019

Therapeutic drug monitoring

Therapeutic Drug Monitoring of Oral Anticancer Drugs: The Dutch Pharmacology Oncology Group-Therapeutic Drug Monitoring Protocol for a Prospective Study.

01-10-2019

Journal of cancer survivorship : research and practice

Implementing physical activity programs for patients with cancer in current practice: patients' experienced barriers and facilitators.

01-10-2019

Cell reports

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

01-10-2019

EBioMedicine

Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry.

01-10-2019

Annals of oncology : official journal of the European Society for Medical Oncology

When is off-label off-road?

01-10-2019

Nature

Inducing and exploiting vulnerabilities for the treatment of liver cancer.

01-10-2019

Clinical pharmacokinetics

Predictive Value of Microdose Pharmacokinetics.

01-10-2019

Nature communications

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

23-09-2019

Nucleic acids research

Sharp kinking of a coiled-coil in MutS allows DNA binding and release.

19-09-2019

Bioorganic & medicinal chemistry letters

A fragment-like approach to PYCR1 inhibition.

15-09-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.

15-09-2019

Nature communications

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

13-09-2019

Communications biology

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

12-09-2019

Frontiers in immunology

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

12-09-2019

Pharmaceutical research

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

11-09-2019

Journal of pharmaceutical and biomedical analysis

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

10-09-2019

BMC cancer

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

10-09-2019

Cell

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

05-09-2019

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

05-09-2019

JAMA network open

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

04-09-2019

Molecular pharmaceutics

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

03-09-2019

Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers.

Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?

Epi-ID: Systematic and Direct Screening for Chromatin Regulators in Yeast by Barcode-ChIP-Seq.

Tetraspanin CD151 and integrin α3β1 contribute to the stabilization of integrin α6β4-containing cell-matrix adhesions.

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study.

Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers.

Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.

Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.

Circulating biomarkers for early detection and clinical management of colorectal cancer.

The Promise of Neoadjuvant Immunotherapy and Surgery for Cancer Treatment.

Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer With a Hepatic Transplant.

Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program.

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer.

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME).

Correction to: Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

Geometrical and dosimetric evaluation of breast target volume auto-contouring.

The molecular genetic make-up of male breast cancer.

Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab.

An international perspective on integrating physiotherapists in oncology care.

Simultaneous Quantification of Free Adalimumab and Infliximab in Human Plasma Using a Target-Based Sample Purification and Liquid Chromatography-Tandem Mass Spectrometry.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

The promise of IO and IOTECH.

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.

Second-Line Cabazitaxel Treatment in Castration-Resistant Prostate Cancer Clinical Trials Compared to Standard of Care in CAPRI: Observational Study in the Netherlands.

Therapeutic Drug Monitoring of Oral Anticancer Drugs: The Dutch Pharmacology Oncology Group-Therapeutic Drug Monitoring Protocol for a Prospective Study.

Implementing physical activity programs for patients with cancer in current practice: patients' experienced barriers and facilitators.

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry.

When is off-label off-road?

Inducing and exploiting vulnerabilities for the treatment of liver cancer.

Predictive Value of Microdose Pharmacokinetics.

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Sharp kinking of a coiled-coil in MutS allows DNA binding and release.

A fragment-like approach to PYCR1 inhibition.

A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

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