Publications

Cancer chemotherapy and pharmacology

Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma.

17-01-2025

Nederlands tijdschrift voor geneeskunde

[Trajectories of health-related quality of life and symptom burden in patients with advanced cancer towards the end of life: longitudinal results from the eQuiPe study].

16-01-2025

Urologic oncology

Development of TAR-200: A novel targeted releasing system designed to provide sustained delivery of gemcitabine for patients with bladder cancer.

15-01-2025

Nature communications

Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies.

14-01-2025

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Adverse health outcomes and health-related quality of life (HRQoL) among long-term adolescent and young adult (AYA) brain tumour survivors: results from the population-based SURVAYA study.

14-01-2025

Immunity

Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation.

14-01-2025

Cancer discovery

Conquering Overtreatment of DCIS: Lessons from PRECISION.

13-01-2025

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Supervised Exercise for Patients With Metastatic Breast Cancer: A Cost-Utility Analysis Alongside the PREFERABLE-EFFECT Randomized Controlled Trial.

13-01-2025

Brain imaging and behavior

Effect of physical exercise on white matter microstructure in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study).

13-01-2025

Cancer discovery

Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.

13-01-2025

Blood

Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B-cell Lymphoma.

10-01-2025

Science advances

NAC regulates metabolism and cell fate in intestinal stem cells.

10-01-2025

International journal of radiation oncology, biology, physics

Radiation Doses to the Breast and Predicted Breast Cancer Risk Among Patients Treated for Hodgkin Lymphoma With Modern Radiation Therapy.

08-01-2025

Frontiers in immunology

Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.

08-01-2025

Proceedings of the National Academy of Sciences of the United States of America

Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.

07-01-2025

Genes & development

BRCA1 and BRCA2: from cancer susceptibility to synthetic lethality.

07-01-2025

Developmental cell

DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma.

07-01-2025

Cell death and differentiation

Apoptotic priming in senescence predicts specific senolysis by quantitative analysis of mitochondrial dependencies.

06-01-2025

Molecular cell

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF.

02-01-2025

The New England journal of medicine

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.

02-01-2025

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

01-01-2025

ESMO open

The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies: results from the Drug Rediscovery Protocol (DRUP).

01-01-2025

Gastroenterology

Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study.

01-01-2025

European journal of cancer (Oxford, England : 1990)

Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.

01-01-2025

Gastroenterology

Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study.

01-01-2025

Gynecologic oncology

Less is more: The benefits of reduced follow-up in gynecologic cancers.

01-01-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Protocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer.

01-01-2025

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Moving beyond barriers: a mixed-method study to develop evidence-based strategies to improve implementation of PROMs in clinical oncology care.

01-01-2025

European radiology

Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis.

01-01-2025

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Development of a prediction model for clinically-relevant fatigue: a multi-cancer approach.

01-01-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.

01-01-2025

Head & neck

The association between skeletal muscle mass and sensorineural hearing loss upon cisplatin-based chemoradiotherapy in patients with head and neck squamous cell carcinoma.

01-01-2025

Journal of vascular and interventional radiology : JVIR

The Influence of Preablation Embolization Particle Size on the Size of the Microwave Ablation Zone in a Porcine Orthotopic Renal Tumor Model.

01-01-2025

Nature

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

01-01-2025

Alimentary pharmacology & therapeutics

Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study.

01-01-2025

Lung cancer (Amsterdam, Netherlands)

Impact of HA-PCI on self-reported cognitive functioning and brain metastases in small-cell lung cancer: Pooled findings of NCT01780675 and PREMER trials.

01-01-2025

Nature medicine

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial.

01-01-2025

Magnetic resonance imaging

vSHARP: Variable Splitting Half-quadratic ADMM algorithm for reconstruction of inverse-problems.

01-01-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

01-01-2025

FEBS letters

Cytosolic-enhanced dark Epac-based FRET sensors allow for intracellular cAMP detection in live cells via FLIM.

31-12-2024

European radiology

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

31-12-2024

Genome biology

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.

31-12-2024

Breast cancer research : BCR

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.

29-12-2024

Frontiers in immunology

Clinical-scale, modular manufacturing of tumor-reactive TILs using a closed and automated culture system.

24-12-2024

Neuro-oncology

Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) for small cell lung cancer better preserves white matter networks compared to conventional PCI.

24-12-2024

Proceedings of the National Academy of Sciences of the United States of America

An antibiotic that mediates immune destruction of senescent cancer cells.

24-12-2024

Genome research

Characterization of DNA methylation reader proteins in Arabidopsis thaliana.

23-12-2024

Cell death and differentiation

Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state.

21-12-2024

STAR protocols

Protocol for studying macrophage lipid crosstalk with murine tumor cells.

20-12-2024

Molecular cell

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

19-12-2024