Publications

Molecular oncology

Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents.

01-06-2018

Life science alliance

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1.

01-06-2018

British journal of clinical pharmacology

Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides.

01-06-2018

American journal of clinical dermatology

Advanced Melanoma: Current Treatment Options, Biomarkers, and Future Perspectives.

01-06-2018

European journal of cancer (Oxford, England : 1990)

Corrigendum to "An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint^®)" [Eur J Cancer 75 (April 2017) 5-13].

01-06-2018

Oral oncology

Comparative genomic analysis of oral versus laryngeal and pharyngeal cancer.

01-06-2018

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and ¹¹C-Erlotinib PET.

01-06-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Retrospective self-sorted 4D-MRI for the liver.

01-06-2018

Cell research

A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma.

01-06-2018

British journal of clinical pharmacology

Development of a nomogram for the estimation of long-term adherence to clozapine therapy using neutrophil fluorescence.

01-06-2018

Nucleic acids research

Easy quantification of template-directed CRISPR/Cas9 editing.

01-06-2018

The Journal of urology

Lymphatic Drainage from Renal Tumors In Vivo: A Prospective Sentinel Node Study Using SPECT/CT Imaging.

01-06-2018

Gynecologic oncology

Course of chemotherapy-induced peripheral neuropathy and its impact on health-related quality of life among ovarian cancer patients: A longitudinal study.

01-06-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

A systematic review of the measurement properties of the Body Image Scale (BIS) in cancer patients.

01-06-2018

Hepatology communications

Telomerase reverse transcriptase mutations in plasma DNA in patients with hepatocellular carcinoma or cirrhosis: Prevalence and risk factors.

01-06-2018

Investigational new drugs

ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.

01-06-2018

Journal of pharmacokinetics and pharmacodynamics

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens.

01-06-2018

European journal of human genetics : EJHG

The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

01-06-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Survivorship care plans have a negative impact on long-term quality of life and anxiety through more threatening illness perceptions in gynecological cancer patients: the ROGY care trial.

01-06-2018

Cell

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.

31-05-2018

Journal of medical Internet research

Online Self-Administered Cognitive Testing Using the Amsterdam Cognition Scan: Establishing Psychometric Properties and Normative Data.

30-05-2018

Oncotarget

Sponge-supported cultures of primary head and neck tumors for an optimized preclinical model.

18-05-2018

Genes

Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study.

17-05-2018

The EMBO journal

Anti-cancer therapy: senescence is the new black.

15-05-2018

Neuroepidemiology

Mild Cognitive Impairment and Dementia Show Contrasting Associations with Risk of Cancer.

15-05-2018

Immunity

Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity.

15-05-2018

Cell reports

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

15-05-2018

Scientific reports

Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.

14-05-2018

Journal of medical Internet research

Barriers and Facilitators Affecting Patient Portal Implementation from an Organizational Perspective: Qualitative Study.

11-05-2018

The New England journal of medicine

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma.

10-05-2018

Cell host & microbe

KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.

09-05-2018

Nucleic acids research

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

04-05-2018

Journal of biomedical optics

Navigating surgical fluorescence cameras using near-infrared optical tracking.

01-05-2018

Bioorganic & medicinal chemistry letters

A multi-gram-scale stereoselective synthesis of Z-endoxifen.

01-05-2018

British journal of cancer

Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers.

01-05-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Demographic, clinical, lifestyle-related, and social-cognitive correlates of physical activity in head and neck cancer survivors.

01-05-2018

Annals of surgery

Cause-specific Mortality in a Population-based Cohort of 9799 Women Treated for Ductal Carcinoma In Situ.

01-05-2018

The Lancet. Oncology

Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial.

01-05-2018

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical morbidity and mortality after neoadjuvant chemotherapy in the CRITICS gastric cancer trial.

01-05-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A secondary analysis of FDG spatio-temporal consistency in the randomized phase II PET-boost trial in stage II-III NSCLC.

01-05-2018

European journal of radiology

CT texture analysis in colorectal liver metastases and the surrounding liver parenchyma and its potential as an imaging biomarker of disease aggressiveness, response and survival.

01-05-2018

The Laryngoscope

Development and external validation of a risk-prediction model to predict 5-year overall survival in advanced larynx cancer.

01-05-2018

Annals of oncology : official journal of the European Society for Medical Oncology

RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

01-05-2018

Lung cancer (Amsterdam, Netherlands)

Physical behavior and associations with health outcomes in operable NSCLC patients: A prospective study.

01-05-2018

Angiogenesis

Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab.

01-05-2018

Clinical pharmacokinetics

Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial.

01-05-2018

The British journal of surgery

Association between hospital volume and quality of gastric cancer surgery in the CRITICS trial.

01-05-2018

Cancer chemotherapy and pharmacology

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.

01-05-2018

Human mutation

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

01-05-2018

Immunology

The opposing roles of CD4⁺ T cells in anti-tumour immunity.

27-04-2018