Publications

EBioMedicine

Molecular profiling of longitudinally observed small colorectal polyps: A cohort study.

01-01-2019

European journal of cancer (Oxford, England : 1990)

A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.

01-01-2019

Genome medicine

Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response.

28-12-2018

Disability and Rehabilitation

Structured clinical reasoning for exercise prescription in patients with comorbidity

21-12-2018

Journal of translational medicine

Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery.

19-12-2018

Nature communications

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.

17-12-2018

Molecular & cellular oncology

With great power comes great vulnerability.

14-12-2018

The Journal of biological chemistry

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.

14-12-2018

Oncoimmunology

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

14-12-2018

Cell

NKG2A, a New Kid on the Immune Checkpoint Block.

13-12-2018

Scandinavian journal of urology

Outcome of sentinel lymph node biopsy in patients with clinically non-metastatic renal cell carcinoma.

12-12-2018

Frontiers in immunology

Functional Heterogeneity of CD4⁺ Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC.

07-12-2018

Science (New York, N.Y.)

LZTR1 is a regulator of RAS ubiquitination and signaling.

07-12-2018

BMC cancer

Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels.

03-12-2018

EJNMMI research

An analysis of SPECT/CT non-visualization of sentinel lymph nodes in renal tumors.

03-12-2018

The Journal of experimental medicine

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.

03-12-2018

British journal of clinical pharmacology

Therapeutic drug monitoring of small molecule kinase inhibitors in oncology in a real-world cohort study: does age matter?

01-12-2018

International journal of care coordination

Turning teams and pathways into integrated practice units: Appearance characteristics and added value.

01-12-2018

Acta oto-laryngologica

Direct complications and routine ICU admission after total laryngectomy.

01-12-2018

Climacteric : the journal of the International Menopause Society

Does anti-Müllerian hormone predict change in menopausal symptoms following risk-reducing salpingo-oophorectomy? A prospective observational study.

01-12-2018

Cancer metastasis reviews

Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment.

01-12-2018

The oncologist

Cluster Analysis Demonstrates the Need to Individualize Care for Cancer Survivors.

01-12-2018

Bioinformatics (Oxford, England)

Modelling signalling networks from perturbation data.

01-12-2018

The Lancet. Oncology

Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial.

01-12-2018

Annals of surgery

Surgicopathological Quality Control and Protocol Adherence to Lymphadenectomy in the CRITICS Gastric Cancer Trial.

01-12-2018

JCO clinical cancer informatics

American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond-Lessons Learned and Member Institutions' Perspectives.

01-12-2018

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative bioanalytical assay for the tropomyosin receptor kinase inhibitor larotrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

01-12-2018

Insights into imaging

Radiomics: a critical step towards integrated healthcare.

01-12-2018

Reproductive sciences (Thousand Oaks, Calif.)

Acute Drug Effects on the Human Placental Tissue: The Development of a Placental Murine Xenograft Model.

01-12-2018

Molecular & cellular proteomics : MCP

Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation.

01-12-2018

Investigational new drugs

Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.

01-12-2018

Breast (Edinburgh, Scotland)

Therapeutic Drug Monitoring of endoxifen as an alternative for CYP2D6 genotyping in individualizing tamoxifen therapy.

01-12-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Cancer survivors not participating in observational patient-reported outcome studies have a lower survival compared to participants: the population-based PROFILES registry.

01-12-2018

International journal of computer assisted radiology and surgery

Accuracy assessment of wireless transponder tracking in the operating room environment.

01-12-2018

British journal of clinical pharmacology

Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.

01-12-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study.

01-12-2018

Leukemia

Risk of subsequent myeloid neoplasms after radiotherapy treatment for a solid cancer among adults in the United States, 2000-2014.

01-12-2018

Life science alliance

Direct binding of Cdt2 to PCNA is important for targeting the CRL4^Cdt2 E3 ligase activity to Cdt1.

01-12-2018

EMBO molecular medicine

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation.

01-12-2018

United European gastroenterology journal

Risks for lymphoma and gastrointestinal carcinoma in patients with newly diagnosed adult-onset celiac disease: Consequences for follow-up: Celiac disease, lymphoma and GI carcinoma.

01-12-2018

Cancer research

Nedd4-Binding Protein 1 and TNFAIP3-Interacting Protein 1 Control MHC-1 Display in Neuroblastoma.

01-12-2018

Journal of pharmaceutical and biomedical analysis

Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates.

30-11-2018

Nucleic acids research

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.

30-11-2018

Genome medicine

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

27-11-2018

Nature communications

Integrative epigenetic taxonomy of primary prostate cancer.

21-11-2018

Nature biotechnology

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

19-11-2018

Breast cancer research : BCR

Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study.

15-11-2018

Key

Clinical cancer research : an official journal of the American Association for Cancer Research

MELK Inhibition in Diffuse Intrinsic Pontine Glioma.

15-11-2018

International journal of radiation oncology, biology, physics

Quantitative Imaging for Radiation Oncology.

15-11-2018

International journal of radiation oncology, biology, physics

A Self-Sorting Coronal 4D-MRI Method for Daily Image Guidance of Liver Lesions on an MR-LINAC.

15-11-2018