Publications

Nature

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB.

14-08-2003

Acta oncologica (Stockholm, Sweden)

Psychosocial issues in cancer genetics--current status and future directions.

06-08-2003

Anti-cancer drugs

Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin.

01-08-2003

Seminars in cancer biology

Ras interference as cancer therapy.

01-08-2003

BioTechniques

Epigenomic profiling using microarrays.

01-08-2003

PDA journal of pharmaceutical science and technology

Pharmaceutical quality control of the investigational polymer-conjugated platinum anticancer agent AP 5280.

25-07-2003

The New England journal of medicine

High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.

03-07-2003

Journal of the National Cancer Institute

Roles of radiation dose, chemotherapy, and hormonal factors in breast cancer following Hodgkin's disease.

02-07-2003

Journal of the National Cancer Institute

Potential for bias in studies on efficacy of prophylactic surgery for BRCA1 and BRCA2 mutation.

02-07-2003

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

High response rates and lasting remissions after low-dose involved field radiotherapy in indolent lymphomas.

01-07-2003

Human reproduction (Oxford, England)

Increased risk of early menopausal transition and natural menopause after poor response at first IVF treatment.

01-07-2003

Clinical cancer research : an official journal of the American Association for Cancer Research

Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein.

01-07-2003

Anti-cancer drugs

In vitro pharmacokinetic study of the novel anticancer agent E7070: red blood cell and plasma protein binding in human blood.

01-07-2003

The Netherlands journal of medicine

Compassionate use programme of irinotecan in colorectal cancer patients in The Netherlands.

01-07-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

01-07-2003

Laboratory animals

Cannulation of the jugular vein in mice: a method for serial withdrawal of blood samples.

01-07-2003

The Journal of biological chemistry

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

27-06-2003

The EMBO journal

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension.

16-06-2003

Nederlands tijdschrift voor geneeskunde

[Trends in the incidence and prevalence of cancer and in the survival of patients in southeastern Netherlands, 1970-1999].

07-06-2003

Medical physics

Focal spot motion of linear accelerators and its effect on portal image analysis.

01-06-2003

Therapeutic drug monitoring

Sorption of thiotepa to polyurethane catheter causes falsely elevated plasma levels.

01-06-2003

Journal of leukocyte biology

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty.

01-06-2003

Oncogene

LOH of PTPRJ occurs early in colorectal cancer and is associated with chromosomal loss of 18q12-21.

29-05-2003

The Journal of biological chemistry

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

16-05-2003

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Serum soluble CD27, but not thymidine kinase, is an independent prognostic factor for outcome in indolent non-Hodgkin's lymphoma.

14-05-2003

Molecular and cellular biology

Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.

01-05-2003

Journal of mass spectrometry : JMS

Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.

01-05-2003

Investigational new drugs

Pharmacokinetic-pharmacodynamic guided trial design in oncology.

01-05-2003

Human mutation

IVS10-6T>G, an ancient ATM germline mutation linked with breast cancer.

01-05-2003

Annual review of biophysics and biomolecular structure

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

16-04-2003

Population health metrics

Estimating the prevalence of breast cancer using a disease model: data problems and trends.

14-04-2003

The Journal of biological chemistry

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

04-04-2003

International journal of radiation oncology, biology, physics

Three-dimensional analysis of delineation errors, setup errors, and organ motion during radiotherapy of bladder cancer.

01-04-2003

Advances in cancer research

Retroviral insertional mutagenesis: tagging cancer pathways.

01-04-2003

Cancer research

Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.

15-03-2003

British journal of cancer

The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancer.

10-03-2003

Cell

The histone minority report: the variant shall not be silenced.

07-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.

04-03-2003

Proceedings of the National Academy of Sciences of the United States of America

Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding.

04-03-2003

Nederlands tijdschrift voor geneeskunde

[From gene to disease; ataxia telangiectasia].

01-03-2003

Anti-cancer drugs

Metabolism of paclitaxel in mice.

01-03-2003

Journal of pharmaceutical and biomedical analysis

Development of a LC method for pharmaceutical quality control of the antimetastatic ruthenium complex NAMI-A.

26-02-2003

The EMBO journal

The alternating ATPase domains of MutS control DNA mismatch repair.

03-02-2003

Therapeutic drug monitoring

High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.

01-02-2003

Annals of oncology : official journal of the European Society for Medical Oncology

Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer.

01-02-2003

The Journal of pharmacology and experimental therapeutics

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir.

01-02-2003

Anti-cancer drugs

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.

01-02-2003

Advanced drug delivery reviews

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21-01-2003

The Biochemical journal

Ceramide: second messenger or modulator of membrane structure and dynamics?

15-01-2003

Journal of cell science

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

15-01-2003