Publications

Proteins

Insights into the DNA cleavage mechanism of human LINE-1 retrotransposon endonuclease.

01-03-2009

Rapid communications in mass spectrometry : RCM

Validated assay for the simultaneous quantification of total vincristine and actinomycin-D concentrations in human EDTA plasma and of vincristine concentrations in human plasma ultrafiltrate by high-performance liquid chromatography coupled with tandem mass spectrometry.

01-03-2009

European journal of nuclear medicine and molecular imaging

Noninvasive functional imaging of P-glycoprotein-mediated doxorubicin resistance in a mouse model of hereditary breast cancer to predict response, and assign P-gp inhibitor sensitivity.

01-03-2009

Journal of pharmaceutical and biomedical analysis

Development and validation of an anion-exchange LC-UV method for the quantification and purity determination of the DNA plasmid pDERMATT.

20-02-2009

Hereditary cancer in clinical practice

The contribution of CHEK2 to the TP53-negative Li-Fraumeni phenotype.

17-02-2009

Structure (London, England : 1993)

"Conditional Restraints": Restraining the Free Atoms in ARP/wARP.

13-02-2009

Molecular cell

Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro.

13-02-2009

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Estradiol and testosterone levels are lower after oophorectomy than after natural menopause.

06-02-2009

Chromosoma

Chromatin domains in higher eukaryotes: insights from genome-wide mapping studies.

01-02-2009

Drug metabolism and disposition: the biological fate of chemicals

Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).

01-02-2009

Cancer chemotherapy and pharmacology

Carbamazepine induces bioactivation of cyclophosphamide and thiotepa.

01-02-2009

Journal of pharmacokinetics and pharmacodynamics

Covariate-based dose individualization of the cytotoxic drug indisulam to reduce the risk of severe myelosuppression.

01-02-2009

Clinical pharmacology and therapeutics

Novel clinical trial designs for innovative therapies.

01-02-2009

Cancer biotherapy & radiopharmaceuticals

A simple and safe method for 131I radiolabeling of rituximab for myeloablative high-dose radioimmunotherapy.

01-02-2009

Investigational new drugs

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib.

01-02-2009

Therapeutic drug monitoring

Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.

01-02-2009

Cancer treatment reviews

An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment.

01-02-2009

Nature reviews. Cancer

Senescence-messaging secretome: SMS-ing cellular stress.

01-02-2009

The Laryngoscope

Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response?

01-02-2009

Advanced drug delivery reviews

Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice.

31-01-2009

BMC bioinformatics

Analysis of mass spectrometry data using sub-spectra.

30-01-2009

Epigenetics & chromatin

High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model.

29-01-2009

Journal of cell science

Integrin alpha3beta1 inhibits directional migration and wound re-epithelialization in the skin.

15-01-2009

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.

01-01-2009

Cancer chemotherapy and pharmacology

Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency.

01-01-2009

Drug metabolism and disposition: the biological fate of chemicals

Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone.

01-01-2009

British journal of clinical pharmacology

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.

01-01-2009

Current clinical pharmacology

Evaluation of human plasma protein binding of trabectedin (Yondelis, ET-743).

01-01-2009

Biochimica et biophysica acta

Protein phosphatase 2A regulatory subunits and cancer.

01-01-2009

European journal of cancer (Oxford, England : 1990)

The frequency, magnitude and timing of post-diagnosis body weight gain in Dutch breast cancer survivors.

01-01-2009

The international journal of biochemistry & cell biology

Molecular basis of the anti-cancer effects of histone deacetylase inhibitors.

01-01-2009

Breast cancer research and treatment

Comparison of gene expression profiles predicting progression in breast cancer patients treated with tamoxifen.

01-01-2009

International journal of radiation oncology, biology, physics

Bowel, urinary, and sexual problems among long-term prostate cancer survivors: a population-based study.

01-01-2009

International journal of technology assessment in health care

Constructive Technology Assessment (CTA) as a tool in coverage with evidence development: the case of the 70-gene prognosis signature for breast cancer diagnostics.

01-01-2009

Breast cancer research and treatment

Stage migration due to introduction of the sentinel node procedure: a population-based study.

01-01-2009

BMC cancer

Haptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients.

24-12-2008

Breast cancer research : BCR

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.

23-12-2008

Immunity

Expression of costimulatory ligand CD70 on steady-state dendritic cells breaks CD8+ T cell tolerance and permits effective immunity.

19-12-2008

Chembiochem : a European journal of chemical biology

Chemical biology approaches to probe the proteome.

15-12-2008

Clinical cancer research : an official journal of the American Association for Cancer Research

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

15-12-2008

Clinical drug investigation

Ciprofloxacin strongly inhibits clozapine metabolism: two case reports.

11-12-2008

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Roles of radiotherapy and chemotherapy in the development of contralateral breast cancer.

01-12-2008

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Propofol extravasation in a breast cancer patient.

01-12-2008

BJU international

Does diabetes mellitus as a comorbid condition affect the health-related quality of life in prostate cancer survivors? Results of a population-based observational study.

01-12-2008

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Using patient-reported outcomes in clinical practice: proceedings of an International Society of Quality of Life Research conference.

01-12-2008

Journal of computational biology : a journal of computational molecular cell biology

Biclustering sparse binary genomic data.

01-12-2008

Cell

RNAi Delivers Insights into Liver Cancer.

28-11-2008

Oncogene

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

20-11-2008

Breast cancer research : BCR

A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer.

19-11-2008

Nederlands tijdschrift voor geneeskunde

[Breast cancer in young women: epidemiology and treatment dilemmas].

15-11-2008