Publications

Journal of gastroenterology

Excess weight among colorectal cancer survivors: target for intervention.

01-09-2012

Cell

Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.

31-08-2012

Sub-cellular biochemistry

Cdt1 and geminin in DNA replication initiation.

25-08-2012

Oncogene

Targeting the epigenome for treatment of cancer.

23-08-2012

BMC research notes

Scenario drafting to anticipate future developments in technology assessment.

16-08-2012

Journal of the American Chemical Society

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

15-08-2012

Cell death & disease

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.

09-08-2012

Annals of oncology : official journal of the European Society for Medical Oncology

The Dutch Childhood Oncology Group guideline for follow-up of asymptomatic cardiac dysfunction in childhood cancer survivors.

01-08-2012

Investigational new drugs

Two-stage model-based design of cancer phase I dose escalation trials: evaluation using the phase I program of barasertib (AZD1152).

01-08-2012

Cancer prevention research (Philadelphia, Pa.)

Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.

01-08-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Impact of negative margin width on local recurrence in breast conserving therapy.

01-08-2012

Journal of cancer research and clinical oncology

Chemotherapy as primary treatment for brain metastases from breast cancer: analysis of 115 one-year survivors.

01-08-2012

Breast (Edinburgh, Scotland)

Axillary and systemic treatment of patients with breast cancer and micrometastatic disease or isolated tumor cells in the sentinel lymph node.

01-08-2012

Oncoimmunology

Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

01-08-2012

British journal of clinical pharmacology

Model-based treatment optimization of a novel VEGFR inhibitor.

01-08-2012

Investigational new drugs

Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.

01-08-2012

Diabetologia

Disease-specific mortality among stage I-III colorectal cancer patients with diabetes: a large population-based analysis.

01-08-2012

BMC health services research

Exploring improvements in patient logistics in Dutch hospitals with a survey.

01-08-2012

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular-signal-regulated kinase and DNA in circulating tumor cells.

01-08-2012

PLoS genetics

A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.

19-07-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection.

15-07-2012

The Journal of biological chemistry

Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

06-07-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Pre-treatment imaging and pathology characteristics of invasive breast cancers of limited extent: potential relevance for MRI-guided localized therapy.

01-07-2012

Oncoimmunology

TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.

01-07-2012

European journal of nuclear medicine and molecular imaging

Concomitant radio- and fluorescence-guided sentinel lymph node biopsy in squamous cell carcinoma of the oral cavity using ICG-(99m)Tc-nanocolloid.

01-07-2012

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Relationship between intraprostatic tracer deposits and sentinel lymph node mapping in prostate cancer patients.

01-07-2012

European journal of cancer (Oxford, England : 1990)

Five-year quality of life of endometrial cancer patients treated in the randomised Post Operative Radiation Therapy in Endometrial Cancer (PORTEC-2) trial and comparison with norm data.

01-07-2012

Drug metabolism and disposition: the biological fate of chemicals

Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine.

01-07-2012

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Comparing the hybrid fluorescent-radioactive tracer indocyanine green-99mTc-nanocolloid with 99mTc-nanocolloid for sentinel node identification: a validation study using lymphoscintigraphy and SPECT/CT.

01-07-2012

Head & neck

Five-year quality of life results of the randomized clinical phase III (RADPLAT) trial, comparing concomitant intra-arterial versus intravenous chemoradiotherapy in locally advanced head and neck cancer.

01-07-2012

PloS one

Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish.

30-06-2012

The oncologist

Concise drug review: pazopanib and axitinib.

27-06-2012

Cancer discovery

Tracking evolution of BRCA1-associated breast cancer.

01-06-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Adaptive radiotherapy for long course neo-adjuvant treatment of rectal cancer.

01-06-2012

Annals of surgical oncology

Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer.

01-06-2012

Cancer chemotherapy and pharmacology

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study.

01-06-2012

Medical physics

TU-E-BRCD-01: The Emerging Role of Image-Guidance for Breast Radiotherapy.

01-06-2012

Current oncology reports

Immunological heterogeneity of the RCC microenvironment: do targeted therapies influence immune response?

01-06-2012

Breast cancer research and treatment

Importance of highly selective LC-MS/MS analysis for the accurate quantification of tamoxifen and its metabolites: focus on endoxifen and 4-hydroxytamoxifen.

01-06-2012

Biochemical Society transactions

The role of UBL domains in ubiquitin-specific proteases.

01-06-2012

Archives of otolaryngology--head & neck surgery

Total laryngectomy for a dysfunctional larynx after (chemo)radiotherapy.

01-06-2012

Development (Cambridge, England)

The Polycomb group protein Ring1b is essential for pectoral fin development.

01-06-2012

Nederlands tijdschrift voor geneeskunde

[Consent for the secondary use of human residual tissue: the patient is best served by an 'opting-out' procedure].

24-05-2012

Physics in medicine and biology

Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

21-05-2012

Journal of palliative care

Severe cannabinoid intoxication in a patient with non-small-cell lung cancer.

16-05-2012

Genes & development

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.

15-05-2012

PloS one

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

11-05-2012

PloS one

Self-reported physical activity: its correlates and relationship with health-related quality of life in a large cohort of colorectal cancer survivors.

09-05-2012

British journal of cancer

A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours.

08-05-2012

The Journal of clinical investigation

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

01-05-2012