Publications

Alimentary pharmacology & therapeutics

Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study.

01-01-2025

The Journal of molecular diagnostics : JMD

High Prevalence of Chromosomal Rearrangements and LINE Retrotranspositions Detected in Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Tissue.

01-12-2024

Molecular oncology

A scenario-drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology.

01-11-2024

Nature communications

Cancer treatment monitoring using cell-free DNA fragmentomes.

21-10-2024

Cancer discovery

Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers.

30-09-2024

Bioinformatics (Oxford, England)

CIBRA identifies genomic alterations with a system-wide impact on tumor biology.

01-09-2024

Gastroenterology

Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study.

30-08-2024

Gastroenterology

Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study.

28-08-2024

Therapeutic advances in medical oncology

Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer.

23-08-2024

The American journal of gastroenterology

Fecal Immunochemical Test to Detect Colorectal Neoplasia in Lynch Syndrome: A Prospective Multicenter Study.

20-08-2024

PloS one

Head-to-head comparison of composite and individual biomarkers to predict clinical benefit to PD-1 blockade in non-small cell lung cancer.

31-07-2024

The Journal of pathology

Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting.

01-06-2024

Endoscopy

Post-colonoscopy colorectal cancers in a national fecal immunochemical test-based colorectal cancer screening program.

01-05-2024

Cancer cell

Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer.

11-03-2024

The journal of pathology. Clinical research

Aberrant PRDM2 methylation as an early event in serrated lesions destined to evolve into microsatellite-instable colorectal cancers.

01-03-2024

The Lancet. Oncology

The multitarget faecal immunochemical test for improving stool-based colorectal cancer screening programmes: a Dutch population-based, paired-design, intervention study.

01-03-2024

Nature protocols

Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice.

01-03-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

A Dysfunctional T-cell Gene Signature for Predicting Nonresponse to PD-1 Blockade in Non-small Cell Lung Cancer That Is Suitable for Routine Clinical Diagnostics.

16-02-2024

Genetics in medicine : official journal of the American College of Medical Genetics

Impact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnostics.

01-02-2024

Cancers

Identifying Genetic Mutation Status in Patients with Colorectal Cancer Liver Metastases Using Radiomics-Based Machine-Learning Models.

29-11-2023

Cancer research communications

Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case-Control Study.

13-11-2023

Expert review of molecular diagnostics

Cross-sectional risk models using quantitative fecal hemoglobin in colorectal cancer screening: a systematic review.

06-11-2023

Gut

An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles.

01-10-2023

Journal for immunotherapy of cancer

Cell-free DNA approaches for cancer early detection and interception.

01-09-2023

BMJ open

Towards Response ADAptive Radiotherapy for organ preservation for intermediate-risk rectal cancer (preRADAR): protocol of a phase I dose-escalation trial.

15-06-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.

01-03-2023

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Initial Impact of National CRC Screening on Incidence and Advanced Colorectal Cancer.

01-03-2023

The Journal of molecular diagnostics : JMD

A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice.

01-01-2023

BMC cancer

The multitarget fecal immunochemical test versus the fecal immunochemical test for programmatic colorectal cancer screening: a cross-sectional intervention study with paired design.

12-12-2022

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Cost-Effectiveness of Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors Treated with Procarbazine and/or Infradiaphragmatic Radiotherapy.

05-12-2022

European journal of cancer (Oxford, England : 1990)

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

01-12-2022

ESMO open

Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics.

01-12-2022

Epigenetics

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

01-12-2022

World journal of gastrointestinal oncology

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

15-11-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

British journal of cancer

Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors.

01-11-2022

Preventive medicine

Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening.

01-11-2022

The Journal of pathology

Feasibility of whole-genome sequencing-based tumor diagnostics in routine pathology practice.

01-10-2022

Annals of internal medicine

Adenoma Detection Rate and Risk for Interval Postcolonoscopy Colorectal Cancer in Fecal Immunochemical Test-Based Screening : A Population-Based Cohort Study.

01-10-2022

Neoplasia (New York, N.Y.)

Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature.

01-10-2022

Inflammatory bowel diseases

Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

01-09-2022

PloS one

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

26-07-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

The Journal of pathology

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

01-06-2022

Clinical and translational gastroenterology

Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

01-06-2022

BMC cancer

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

08-04-2022

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

01-04-2022

JCO precision oncology

Reply to R. Pham et al.

01-03-2022

JCO clinical cancer informatics

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

01-02-2022

Cancers

Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

16-01-2022