Publications

Nature communications

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.

17-10-2024

Nature communications

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

12-06-2024

Molecular cell

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

16-05-2024

Molecular cell

Freedom to err: The expanding cellular functions of translesion DNA polymerases.

19-10-2023

Bio-protocol

Quantification of Chromosomal Aberrations in Mammalian Cells.

20-08-2023

Molecular & cellular proteomics : MCP

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

01-06-2023

Journal of lipid research

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

01-05-2023

Nature communications

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

08-09-2022

Nature communications

MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair.

14-09-2021

Trends in cell biology

REV7: Jack of many trades.

01-08-2021

Oncogene

H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres.

01-06-2020

Nature cell biology

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

01-08-2018

Cell reports

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

15-05-2018

Cell cycle (Georgetown, Tex.)

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

22-11-2017

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

23-05-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells.

01-05-2016

Molecular cell

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

18-02-2016

Nature

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

28-05-2015

Frontiers in oncology

Loss of telomere protection: consequences and opportunities.

19-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Cell cycle (Georgetown, Tex.)

Posttranslational control of telomere maintenance and the telomere damage response.

15-04-2012

Nucleus (Austin, Tex.)

Fusing telomeres with RNF8.

01-03-2012

Nature cell biology

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

21-08-2011

Oncogene

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

20-11-2008

Cell cycle (Georgetown, Tex.)

p16INK4a as a second effector of the telomere damage pathway.

01-10-2005

Genes & development

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

15-06-2005

The Journal of biological chemistry

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

19-07-2002

Biochimica et biophysica acta

Polycomb repression: from cellular memory to cellular proliferation and cancer.

21-06-2002

Nature genetics

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

01-11-2000

Genes & development

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

15-10-1999

Seminars in cell & developmental biology

Cellular memory of transcriptional states by Polycomb-group proteins.

01-04-1999

Nature

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

14-01-1999

Journal of molecular biology

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

14-11-1997

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

Freedom to err: The expanding cellular functions of translesion DNA polymerases.

Quantification of Chromosomal Aberrations in Mammalian Cells.

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair.

REV7: Jack of many trades.

H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells.

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

Loss of telomere protection: consequences and opportunities.

Senescence: back to telomeres.

Senescence: back to telomeres.

Posttranslational control of telomere maintenance and the telomere damage response.

Fusing telomeres with RNF8.

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

p16INK4a as a second effector of the telomere damage pathway.

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

Polycomb repression: from cellular memory to cellular proliferation and cancer.

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Cellular memory of transcriptional states by Polycomb-group proteins.

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

A single amino acid exchange, Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with high affinity for the chicken EGF receptor

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

This site uses cookies

Publications

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1S824.

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

Freedom to err: The expanding cellular functions of translesion DNA polymerases.

Quantification of Chromosomal Aberrations in Mammalian Cells.

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair.

REV7: Jack of many trades.

H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells.

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

Loss of telomere protection: consequences and opportunities.

Senescence: back to telomeres.

Senescence: back to telomeres.

Posttranslational control of telomere maintenance and the telomere damage response.

Fusing telomeres with RNF8.

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

p16INK4a as a second effector of the telomere damage pathway.

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

Polycomb repression: from cellular memory to cellular proliferation and cancer.

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Cellular memory of transcriptional states by Polycomb-group proteins.

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

A single amino acid exchange, Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with high affinity for the chicken EGF receptor

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene

This site uses cookies

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.