Publications

Cell calcium

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells.

01-12-2013

Biochimica et biophysica acta

cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC.

01-12-2013

Current biology : CB

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

21-10-2013

Nature methods

hiFRET: some tailwind for FRET resolves weak protein interactions.

01-10-2013

Methods in molecular biology (Clifton, N.J.)

Detecting cAMP with an EPAC-based FRET sensor in single living cells.

21-09-2013

Molecular biology of the cell

Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly.

01-04-2012

PloS one

LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor.

24-12-2011

Chembiochem : a European journal of chemical biology

Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression.

16-08-2011

PloS one

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

29-04-2011

BioEssays : news and reviews in molecular, cellular and developmental biology

G protein-coupled receptors: the inside story.

01-01-2010

Molecular biology of the cell

Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.

01-11-2009

Molecular endocrinology (Baltimore, Md.)

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

01-09-2009

Molecular and cellular biology

Direct spatial control of Epac1 by cyclic AMP.

01-05-2009

Journal of microscopy

Immersion oil for high-resolution live-cell imaging at 37 degrees C: optical and physical characteristics.

01-11-2008

PloS one

A comparison of donor-acceptor pairs for genetically encoded FRET sensors: application to the Epac cAMP sensor as an example.

02-04-2008

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

The EMBO journal

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.

08-08-2007

The Journal of cell biology

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate.

04-06-2007

Experimental cell research

Direct measurement of cyclic AMP diffusion and signaling through connexin43 gap junctional channels.

15-01-2007

The Journal of biological chemistry

Activation of TRPM7 channels by phospholipase C-coupled receptor agonists.

05-01-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

01-09-2006

Trends in pharmacological sciences

An emerging role for PtdIns(4,5)P2-mediated signalling in human disease.

01-12-2005

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

01-12-2004

Cancer cell

Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer.

01-06-2004

Biophysical journal

Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission.

01-04-2004

The Journal of biological chemistry

Calcium signaling regulates translocation and activation of Rac.

10-10-2003

Immunity

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

01-01-2003

Molecular biology of the cell

Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale.

01-09-2002

The Journal of biological chemistry

Monitoring agonist-induced phospholipase C activation in live cells by fluorescence resonance energy transfer.

04-05-2001

Current biology : CB

Galpha(13) mediates activation of a depolarizing chloride current that accompanies RhoA activation in both neuronal and nonneuronal cells.

23-01-2001

Electrophoresis

High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.

01-06-1998

Current biology : CB

Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways.

26-03-1998

The Journal of cell biology

Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src.

09-03-1998

The EMBO journal

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

15-05-1996

The EMBO journal

Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor.

02-01-1996

The Biochemical journal

Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis.

15-04-1995

Biochimica et biophysica acta

Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator.

30-12-1994

The Journal of cell biology

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

01-08-1994

The Journal of biological chemistry

cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts.

04-02-1994

The Biochemical journal

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

01-05-1993

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research

Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.

01-04-1993

Proceedings of the National Academy of Sciences of the United States of America

Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae.

01-03-1993

The EMBO journal

Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.

01-07-1992

The Journal of cell biology

Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers.

01-07-1992

The Biochemical journal

Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin.

01-01-1992

Cold Spring Harbor symposia on quantitative biology

Lysophosphatidic acid: a novel phospholipid with hormone- and growth factor-like activities.

01-01-1992