Banner Publications MH200828 N141

Publications

Results found: 1066

Showing results: 401 - 450

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the PI3K/mTOR inhibitor GSK2126458 in mouse plasma and tumor homogenate.

25-03-2015
Pharmacology research & perspectives

Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses.

01-03-2015
European journal of clinical pharmacology

Baclofen overdose treated with continuous venovenous hemofiltration.

01-03-2015
International journal of pharmaceutics

Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy.

01-02-2015
Investigational new drugs

Pharmacokinetics and excretion of (14)C-lenvatinib in patients with advanced solid tumors or lymphomas.

01-02-2015
Investigational new drugs

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.

01-02-2015
Oncoscience

P-gp and taxanes.

17-01-2015
International journal of cancer

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

01-01-2015
Antimicrobial agents and chemotherapy

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis.

01-01-2015
Pharmaceutical research

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) restrict oral availability and brain accumulation of the PARP inhibitor rucaparib (AG-014699).

01-01-2015
Bioanalysis

Quantifying vemurafenib in dried blood spots using high-performance LC-MS/MS.

23-12-2014
Bioanalysis

Determination of tamoxifen and endoxifen in dried blood spots using LC-MS/MS and the effect of coated DBS cards on recovery and matrix effects.

17-12-2014
Investigational new drugs

"Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

01-12-2014
Pediatric blood & cancer

Design of a drug-drug interaction study of vincristine with azole antifungals in pediatric cancer patients using clinical trial simulation.

01-12-2014
Nature communications

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response.

12-11-2014
British journal of cancer

Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option.

28-10-2014
Human gene therapy methods

Manufacture of gene-modified human T-cells with a memory stem/central memory phenotype.

01-10-2014
Drugs & aging

Incidence of hematologic toxicity in older adults treated with gemcitabine or a gemcitabine-containing regimen in routine clinical practice: a multicenter retrospective cohort study.

01-10-2014
Investigational new drugs

Design of informative renal impairment studies: evaluation of the impact of design stratification on bias, precision and dose adjustment error.

01-10-2014
Annals of oncology : official journal of the European Society for Medical Oncology

Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel.

01-10-2014
Bioanalysis

Procedures and practices for the validation of bioanalytical methods using dried blood spots: a review.

01-09-2014
Nederlands tijdschrift voor geneeskunde

[Hyperglycaemia during treatment with everolimus].

15-08-2014
European journal of cancer (Oxford, England : 1990)

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies.

01-08-2014
European journal of cancer (Oxford, England : 1990)

Therapeutic drug monitoring in cancer--are we missing a trick?

01-08-2014
European journal of cancer (Oxford, England : 1990)

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics.

01-08-2014
Breast cancer research and treatment

Use of dried blood spots for the determination of serum concentrations of tamoxifen and endoxifen.

01-07-2014
Clinical cancer research : an official journal of the American Association for Cancer Research

P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice.

15-06-2014
Therapeutic drug monitoring

Plasma concentrations of tyrosine kinase inhibitors imatinib, erlotinib, and sunitinib in routine clinical outpatient cancer care.

01-06-2014
British journal of cancer

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation.

27-05-2014
Clinical cancer research : an official journal of the American Association for Cancer Research

ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy.

15-05-2014
British journal of cancer

Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours.

13-05-2014
Current clinical pharmacology

Phase II and pharmacological study of oral docetaxel plus cyclosporin A in anthracycline pre-treated metastatic breast cancer.

01-05-2014
Anti-cancer drugs

Cellular and clinical pharmacology of the taxanes docetaxel and paclitaxel--a review.

01-05-2014
Clinical pharmacokinetics

Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.

01-04-2014
Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the light sensitive survivin suppressant sepantronium bromide (YM155) in mouse plasma.

01-04-2014
Clinical pharmacology and therapeutics

Herb-drug interactions in oncology.

01-04-2014
Bioanalysis

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

01-04-2014
BioMed research international

Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy.

29-03-2014
International journal of cancer

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.

15-03-2014
Journal of pharmaceutical and biomedical analysis

Quantitative determination of azacitidine triphosphate in peripheral blood mononuclear cells using liquid chromatography coupled with high-resolution mass spectrometry.

01-03-2014
Molecular pharmacology

Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.

01-03-2014
Breast cancer research and treatment

Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care.

01-02-2014
Journal of pharmaceutical sciences

Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling.

01-02-2014
Biomedical chromatography : BMC

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

01-02-2014
Journal of pharmaceutical and biomedical analysis

Development and validation of a high-performance liquid chromatography-tandem mass spectrometry assay quantifying vemurafenib in human plasma.

01-01-2014
BMC cancer

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

28-12-2013
European journal of clinical pharmacology

The effect of seasonal variation and secretion of sunitinib in sweat on the development of hand-foot syndrome.

01-12-2013
Current opinion in pharmacology

Genetically modified mouse models for oral drug absorption and disposition.

01-12-2013
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a high-performance liquid chromatography-tandem mass spectrometry assay quantifying olaparib in human plasma.

01-12-2013
Clinical therapeutics

Bioequivalence of Liposome-Entrapped Paclitaxel Easy-To-Use (LEP-ETU) formulation and paclitaxel in polyethoxylated castor oil: a randomized, two-period crossover study in patients with advanced cancer.

01-12-2013

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