Publications

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

26-08-2024

Key

The regulatory grammar of human promoters uncovered by MPRA-trained deep learning

15-07-2024

Key

The EMBO journal

Chromatin protein complexes involved in gene repression in lamina-associated domains.

01-11-2024

eLife

Large-scale analysis of the integration of enhancer-enhancer signals by promoters.

28-10-2024

bioRxiv : the preprint server for biology

An integrated view of the structure and function of the human 4D nucleome.

27-10-2024

Communications biology

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.

13-09-2024

Nucleic acids research

Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing.

27-08-2024

Nature biotechnology

Publisher Correction: Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

12-08-2024

bioRxiv : the preprint server for biology

Optimized reporters for multiplexed detection of transcription factor activity.

26-07-2024

Nature communications

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

22-06-2024

Nature biotechnology

Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

21-06-2024

Cell reports

Perturbations in 3D genome organization can promote acquired drug resistance.

31-10-2023

Nucleic acids research

Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements.

13-10-2023

Nature

Heritable transcriptional defects from aberrations of nuclear architecture.

01-07-2023

Nucleic acids research

Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR.

23-06-2023

EMBO reports

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki-67.

06-12-2022

DNA repair

From fluorescent foci to sequence: Illuminating DNA double strand break repair by high-throughput sequencing technologies.

01-10-2022

Genome biology

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.

01-09-2022

Molecular cell

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.

07-07-2022

Nature

Nonlinear control of transcription through enhancer-promoter interactions.

01-04-2022

Frontiers in genetics

Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair.

18-02-2022

Methods in molecular biology (Clifton, N.J.)

Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.

02-02-2022

Current opinion in cell biology

Lamina-associated domains: Tethers and looseners.

01-02-2022

Science (New York, N.Y.)

3D genomics across the tree of life reveals condensin II as a determinant of architecture type.

28-05-2021

Molecular cell

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance.

20-05-2021

Open biology

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner.

01-03-2021

Genome biology

SPIN reveals genome-wide landscape of nuclear compartmentalization.

14-01-2021

EMBO reports

Cell cycle dynamics of lamina-associated DNA.

05-11-2020

Developmental cell

Phosphorylated Lamins in Euchromatin: New Clues to Progeria.

23-03-2020

The EMBO journal

Local rewiring of genome-nuclear lamina interactions by transcription.

16-03-2020

Trends in biochemical sciences

Deciphering Gene Regulation Using Massively Parallel Reporter Assays.

01-01-2020

Nature genetics

High-throughput identification of human SNPs affecting regulatory element activity.

01-07-2019

Nature reviews. Molecular cell biology

The role of transcription in shaping the spatial organization of the genome.

01-06-2019

Cell

Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs.

02-05-2019

Methods in molecular biology (Clifton, N.J.)

Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER.

27-03-2019

The Journal of cell biology

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler.

05-11-2018

Epigenetics & chromatin

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a.

01-11-2018

EMBO reports

Scientific honesty and publicly shared lab notebooks: Sharing lab notebooks along with publication would increase transparency and help to improve honesty when reporting results.

01-10-2018

Epigenetics & chromatin

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

03-07-2018

Molecular cell

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

07-06-2018

Epigenetics & chromatin

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

05-06-2018

Nucleic acids research

Easy quantification of template-directed CRISPR/Cas9 editing.

01-06-2018

Life science alliance

CHRAC/ACF contribute to the repressive ground state of chromatin.

01-01-2018

Genome research

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

01-10-2017

PLoS genetics

Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.

01-08-2017

Genome research

Clustering of Drosophila housekeeping promoters facilitates their expression.

01-07-2017

Genome research

Small chromosomal regions position themselves autonomously according to their chromatin class.

01-06-2017

Cell

Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression.

18-05-2017

Cell

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension.

04-05-2017

Molecular cell

Functional Enhancer Screening in Single Cells.

20-04-2017