Publications

Immunological reviews

TCR repertoires of intratumoral T-cell subsets.

01-01-2014

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.

10-11-2013

Nature medicine

High-throughput identification of antigen-specific TCRs by TCR gene capture.

01-11-2013

Journal of immunology (Baltimore, Md. : 1950)

Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer.

15-09-2013

Vaccine

Transposon leads to contamination of clinical pDNA vaccine.

11-07-2013

Science (New York, N.Y.)

Heterogeneous differentiation patterns of individual CD8+ T cells.

03-05-2013

Nature

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

11-04-2013

Current opinion in immunology

Human cancer regression antigens.

01-04-2013

The EMBO journal

The cancer antigenome.

23-01-2013

Chembiochem : a European journal of chemical biology

Development of a hypersensitive periodate-cleavable amino acid that is methionine- and disulfide-compatible and its application in MHC exchange reagents for T cell characterisation.

02-01-2013

Human gene therapy

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

01-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Oncoimmunology

Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

01-08-2012

Oncoimmunology

TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.

01-07-2012

Advances in immunology

Behavior and function of tissue-resident memory T cells.

28-03-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remission.

10-01-2012

Results in immunology

Testing for HLA/peptide tetramer-binding to the T cell receptor complex on human T lymphocytes.

01-01-2012

Cancer immunology, immunotherapy : CII

Combination of targeted therapy and immunotherapy in melanoma.

01-10-2011

The Journal of investigative dermatology

T-cell receptor gene therapy: critical parameters for clinical success.

01-09-2011

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

01-08-2011

International journal of cancer

Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7.

15-07-2011

Annals of the New York Academy of Sciences

The descent of memory T cells.

01-01-2011

Current topics in microbiology and immunology

DNA vaccines and intradermal vaccination by DNA tattooing.

26-11-2010

Human gene therapy

Microbead-assisted retroviral transduction for clinical application.

01-10-2010

Journal of proteomics

Technologies for MHC class I immunoproteomics.

10-09-2010

Nature reviews. Immunology

Mapping the life histories of T cells.

01-09-2010

Cancer immunology, immunotherapy : CII

RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells.

01-08-2010

The Journal of experimental medicine

One naive T cell, multiple fates in CD8+ T cell differentiation.

07-06-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

01-05-2010

Current protocols in immunology

Generation of peptide MHC class I monomers and multimers through ligand exchange.

01-11-2009

Science (New York, N.Y.)

Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient.

04-09-2009

Journal of the American Chemical Society

UV-induced ligand exchange in MHC class I protein crystals.

02-09-2009

Journal of the American Chemical Society

Class I major histocompatibility complexes loaded by a periodate trigger.

02-09-2009

Immunotherapy

Immunotherapeutic strategies: the melanoma example.

01-07-2009

Nature methods

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

01-07-2009

Methods in molecular biology (Clifton, N.J.)

High-throughput T-cell epitope discovery through MHC peptide exchange.

21-04-2009

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

01-04-2009

Current opinion in immunology

Adoptive T cell therapy of cancer.

01-04-2009

Journal of immunology (Baltimore, Md. : 1950)

Requirements for effective antitumor responses of TCR transduced T cells.

01-10-2008

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial.

01-10-2008

The Journal of experimental medicine

Dissecting T cell lineage relationships by cellular barcoding.

29-09-2008

Journal of immunology (Baltimore, Md. : 1950)

TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.

15-08-2008

Journal of immunology (Baltimore, Md. : 1950)

Long-term functionality of TCR-transduced T cells in vivo.

15-05-2008

Journal of immunology (Baltimore, Md. : 1950)

An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.

01-05-2008

Cancer research

Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer.

01-04-2008

Proceedings of the National Academy of Sciences of the United States of America

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.

11-03-2008

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007

Journal of immunology (Baltimore, Md. : 1950)

In vivo antigen stability affects DNA vaccine immunogenicity.

15-08-2007

Blood

Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease.

01-05-2007