Publications

Cell stem cell

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.

02-04-2020

Key

NPJ precision oncology

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression.

28-01-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.

01-01-2025

Nature

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

01-01-2025

Nature biomedical engineering

Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.

10-12-2024

Journal of cell science

Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers.

01-09-2024

Nature

Mechanisms that clear mutations drive field cancerization in mammary tissue.

01-09-2024

iScience

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

16-08-2024

British journal of cancer

Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

01-08-2024

The Journal of pathology

Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.

01-07-2024

Science advances

BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis.

20-10-2023

Cancer cell

Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.

12-06-2023

Journal of visualized experiments : JoVE

Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling.

09-06-2023

Cancer cell

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

08-05-2023

Cold Spring Harbor perspectives in medicine

Multidimensional Imaging of Breast Cancer.

02-05-2023

Developmental cell

A Lamb1Dendra2 mouse model identifies basement-membrane-producing origins and dynamics in PyMT breast tumors.

10-04-2023

Journal of experimental & clinical cancer research : CR

Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer.

03-03-2023

Nature reviews. Cancer

Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

01-02-2023

Nature communications

Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.

31-01-2023

Cell

Coordinated cancer chaos.

19-01-2023

Nature communications

Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.

07-12-2022

Nature reviews. Cancer

Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

01-12-2022

eLife

Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations.

29-11-2022

Cell reports. Medicine

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.

15-11-2022

Nature communications

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

28-10-2022

Developmental cell

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries.

24-10-2022

Nature

Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.

01-09-2022

Nature

Retrograde movements determine effective stem cell numbers in the intestine.

01-07-2022

Cancers

Epithelial-to-Mesenchymal Transition Drives Invasiveness of Breast Cancer Brain Metastases.

25-06-2022

Trends in cancer

Tissue architecture in tumor initiation and progression.

01-06-2022

Cancers

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells.

19-05-2022

Cancer research

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.

16-05-2022

Nature

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.

01-05-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments.

01-03-2022

Journal of visualized experiments : JoVE

Longitudinal Intravital Microscopy Using a Mammary Imaging Window with Replaceable Lid.

20-01-2022

Scientific reports

GFAP splice variants fine-tune glioma cell invasion and tumour dynamics by modulating migration persistence.

10-01-2022

Nature reviews. Methods primers

Multiphoton intravital microscopy of rodents.

01-01-2022

STAR protocols

Generation of mixed murine organoids to model cellular interactions.

17-12-2021

Developmental cell

Distinct contributions of partial and full EMT to breast cancer malignancy.

06-12-2021

Nature chemical biology

Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.

01-11-2021

Developmental dynamics : an official publication of the American Association of Anatomists

LGR6 marks nephron progenitor cells.

01-11-2021

The FEBS journal

Targeting dormant tumor cells to prevent cancer recurrence.

01-11-2021

Oncogene

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation.

01-11-2021

Nature reviews. Cancer

Tissue clearing to examine tumour complexity in three dimensions.

01-11-2021

The EMBO journal

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

18-10-2021

Current opinion in cell biology

Intravital microscopy to illuminate cell state plasticity during metastasis.

01-10-2021

Oncotarget

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing.

17-08-2021

Cell reports

Active elimination of intestinal cells drives oncogenic growth in organoids.

06-07-2021

Journal of clinical medicine

Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States.

29-05-2021

eLife

Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.

26-05-2021