Publications

Molecular oncology

A scenario-drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology.

01-11-2024

Nature communications

Cancer treatment monitoring using cell-free DNA fragmentomes.

21-10-2024

The Journal of molecular diagnostics : JMD

High Prevalence of Chromosomal Rearrangements and LINE Retrotranspositions Detected in Formalin-Fixed, Paraffin-Embedded Colorectal Cancer Tissue.

26-09-2024

Bioinformatics (Oxford, England)

CIBRA identifies genomic alterations with a system-wide impact on tumor biology.

01-09-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).

01-09-2024

Therapeutic advances in medical oncology

Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer.

23-08-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Staging peritoneal metastases in colorectal cancer: The correlation between MRI, surgical and histopathological peritoneal cancer index.

22-08-2024

Frontiers in genetics

Methylenetetrahydrofolate reductase polymorphic variants C677T and A1298C in rectal cancer in Slavic population: significance for cancer risk and response to chemoradiotherapy.

30-01-2024

Journal of clinical medicine

Performance and Dimensionality of Pretreatment MRI Radiomics in Rectal Carcinoma Chemoradiotherapy Prediction.

12-01-2024

Cancers

Identifying Genetic Mutation Status in Patients with Colorectal Cancer Liver Metastases Using Radiomics-Based Machine-Learning Models.

29-11-2023

Cancer research communications

Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case-Control Study.

13-11-2023

International journal of molecular sciences

Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy.

21-10-2023

Frontiers in genetics

Exploring novel genetic and hematological predictors of response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

18-09-2023

BMJ open

Towards Response ADAptive Radiotherapy for organ preservation for intermediate-risk rectal cancer (preRADAR): protocol of a phase I dose-escalation trial.

15-06-2023

Virchows Archiv : an international journal of pathology

Comparison of NTRK fusion detection methods in microsatellite-instability-high metastatic colorectal cancer.

01-06-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.

01-03-2023

The British journal of surgery

Predicting early extrahepatic recurrence after local treatment of colorectal liver metastases.

15-02-2023

The Journal of molecular diagnostics : JMD

A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice.

01-01-2023

European journal of cancer (Oxford, England : 1990)

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

01-12-2022

Neoplasia (New York, N.Y.)

Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature.

01-10-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

Cell genomics

A multi-platform reference for somatic structural variation detection.

08-06-2022

Cancers

External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort.

10-05-2022

Cancers

Cell-Free Circulating (Tumor) DNA before Surgery as a Prognostic Factor in Non-Metastatic Colorectal Cancer: A Systematic Review.

29-04-2022

Communications biology

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.

08-04-2022

BMC cancer

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

08-04-2022

European journal of radiology

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

01-04-2022

JCO precision oncology

Reply to R. Pham et al.

01-03-2022

JCO clinical cancer informatics

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

01-02-2022

GigaScience

Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data.

09-12-2021

JCO precision oncology

KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.

26-11-2021

Annals of internal medicine

Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

01-09-2021

Nature communications

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

20-08-2021

JAMA surgery

Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial.

01-08-2021

EBioMedicine

Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases.

01-08-2021

EMBO reports

Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.

04-06-2021

Proteomics. Clinical applications

Lipopolysaccharide-regulated secretion of soluble and vesicle-based proteins from a panel of colorectal cancer cell lines.

01-05-2021

The journal of pathology. Clinical research

Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.

01-05-2021

BMJ open

First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II).

30-03-2021

European journal of cancer (Oxford, England : 1990)

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer.

01-02-2021

The Journal of molecular diagnostics : JMD

Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer.

01-12-2020

Oncoimmunology

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.

13-10-2020

The European journal of health economics : HEPAC : health economics in prevention and care

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN).

01-09-2020

BMC cancer

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.

20-08-2020

International journal of molecular sciences

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

12-06-2020

Scientific reports

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

15-05-2020

International journal of cancer

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

01-04-2020

The Journal of pathology

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.

01-03-2020

Nature communications

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

27-01-2020

Molecular aspects of medicine

Circulating biomarkers for early detection and clinical management of colorectal cancer.

01-10-2019